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Kmiecik MJ, Micheletti S, Coker D
et al.Show more authors.
Kmiecik MJ, Micheletti S, Coker D, Heilbron K, Shi J, Stagaman K, Sonmez TF, Fontanillas P, Shringarpure S, Wetzel M, Rowbotham HM, Cannon P, Shelton JF, Hinds DA, Tung JY, 23andMe Research Team, Holmes MV, Aslibekyan S, Norcliffe-Kaufmann L
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Genetic analysis and natural history of Parkinson's disease due to the LRRK2 G2019S variant
Brain.06 June 2024.
Neurology
Schormair B, Zhao C, Bell S
et al.Show more authors.
Schormair B, Zhao C, Bell S, Didriksen M, Nawaz MS, Schandra N, Stefani A, Högl B, Dauvilliers Y, Bachmann CG, Kemlink D, Sonka K, Paulus W, Trenkwalder C, Oertel WH, Hornyak M, Teder-Laving M, Metspalu A, Hadjigeorgiou GM, Polo O, Fietze I, Ross OA, Wszolek ZK, Ibrahim A, Bergmann M, Kittke V, Harrer P, Dowsett J, Chenini S, Ostrowski SR, Sørensen E, Erikstrup C, Pedersen OB, Bruun MT, Nielsen KR, Butterworth AS, Soranzo N, Ouwehand WH, Roberts DJ, Danesh J, Burchell B, Furlotte NA, Nandakumar P, 23andMe Research Team, D.E.S.I.R. Study Group, Earley CJ, Ondo WG, Xiong L, Desautels A, Perola M, Vodicka P, Dina C, Stoll M, Franke A, Lieb W, Stewart AFR, Shah SH, Gieger C, Peters A, Rye DB, Rouleau GA, Berger K, Stefansson H, Ullum H, Stefansson K, Hinds DA, Di Angelantonio E, Oexle K, Winkelmann J
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Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction
Nature.05 June 2024.
Traits
Jin J, Zhan J, Zhang J
et al.Show more authors.
Jin J, Zhan J, Zhang J, Zhao R, O’Connell J, Jiang Y, 23andMe Research Team, Aslibekyan S, Auton A, Babalola E, Bell RK, Bielenberg J, Bryc K, Bullis E, Coker D, Cuellar Partida G, Dhamija D, Das S, Elson SL, Eriksson N, Filshtein T, Fitch A, Fletez-Brant K, Fontanillas P, Freyman W, Granka JM, Heilbron K, Hernandez A, Hicks B, Hinds DA, Jewett EM, Kukar K, Kwong A, Lin KH, Llamas BA, Lowe M, McCreight JC, McIntyre MH, Micheletti SJ, Moreno ME, Nandakumar P, Nguyen DT, Noblin ES, Petrakovitz AA, Poznik GD, Reynoso A, Schumacher M, Shastri AJ, Shelton JF, Shi J, Shringarpure S, Su QJ, Tat SA, Tchakouté CT, Tran V, Tung JY, Wang X, Wang W, Weldon CH, Wilton P, Wong CD; Buyske S, Gignoux C, Haiman C, Kenny EE, Kooperberg C, North K, Koelsch BL, Wojcik G, Zhang H, Chatterjee N
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MUSSEL: Enhanced Bayesian polygenic risk prediction leveraging information across multiple ancestry groups
Science.10 April 2024.
Ancestry
Jennings MV, Martínez-Magaña JJ, Courchesne-Krak NS, Cupertino RB
et al.Show more authors.
Jennings MV, Martínez-Magaña JJ, Courchesne-Krak NS, Cupertino RB, Vilar-Ribó LV, Bianchi SB, Hatoum AS, Atkinson EG, Giusti-Rodriguez P, Montalvo-Ortiz JL, Gelernter J, Soler Artigas M, Aslibekyan S, Auton A, Babalola E, Bell RK, Bielenberg J, Bryc K, Bullis E, Coker D, Cuellar Partida G, Dhamija D, Das S, Elson SL, Eriksson N, Filshtein T, Fitch A, Fletez-Brant K, Fontanillas P, Freyman W, Granka JM, Heilbron K, Hernandez A, Hicks B, Hinds DA, Jewett EM, Jiang Y, Kukar K, Kwong A, Lin KH, Llamas BA, Lowe M, McCreight JC, McIntyre MH, Micheletti SJ, Moreno ME, Nandakumar P, Nguyen DT, Noblin ES, O'Connell J, Petrakovitz AA, Poznik GD, Reynoso A, Schumacher M, Shastri AJ, Shelton JF, Shi J, Shringarpure S, Su QJ, Tat SA, Toukam Tchakouté C, Tran V, Tung JY, Wang X, Wang W, Weldon CH, Wilton P, Wong CD, Elson SL, Edenberg HJ, Fontanillas P, Palmer AA, Sanchez-Roige S, 23andMe Research Team
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A phenome-wide association and Mendelian randomisation study of alcohol use variants in a diverse cohort comprising over 3 million individuals
Science Direct.04 April 2024.
Behavior
Pitz V, Makarious MB, Bandres-Ciga S
et al.Show more authors.
Pitz V, Makarious MB, Bandres-Ciga S, Iwaki H, 23andMe Research Team, Singleton AB, Nalls M, Heilbron K, Blauwendraat C
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Analysis of rare Parkinson’s disease variants in millions of people
Nature.08 January 2024.
Neurology
Meng X, Navoly G, Giannakopoulou O
et al.Show more authors.
Meng X, Navoly G, Giannakopoulou O, Levey DF, Koller D, Pathak GA, Koen N, Lin K, Adams MJ, Rentería ME, Feng Y, Gaziano JM, Stein DJ, Zar HJ, Campbell ML, van Heel DA, Trivedi B, Finer S, McQuillin A, Bass N, Chundru VK, Martin HC, Huang QQ, Valkovskaya M, Chu CY, Kanjira S, Kuo PH, Chen HC, Tsai SJ, Liu YL, Kendler KS, Peterson RE, Cai N, Fang Y, Sen S, Scott LJ, Burmeister M, Loos RJF, Preuss MH, Actkins KV, Davis LK, Uddin M, Wani AH, Wildman DE, Aiello AE, Ursano RJ, Kessler RC, Kanai M, Okada Y, Sakaue S, Rabinowitz JA, Maher BS, Uhl G, Eaton W, Cruz-Fuentes CS, Martinez-Levy GA, Campos AI, Millwood IY, Chen Z, Li L, Wassertheil-Smoller S, Jiang Y, Tian C, Martin NG, Mitchell BL, Byrne EM, Awasthi S, Coleman JRI, Ripke S, PGC-MDD Working Group, China Kadoorie Biobank Collaborative Group, 23andMe Research Team, Genes and Health Research Team, BioBank Japan Project, Sofer T, Walters RG, McIntosh AM, Polimanti R, Dunn EC, Stein MB, Gelernter J, Lewis CM, Kuchenbaecker KK
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Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference
Nature Genetics.04 January 2024.
Psychiatry
Kim JJ, Vitale D, Otani DV
et al.Show more authors.
Kim JJ, Vitale D, Otani DV, Lian MM, Heilbron K, Iwaki H, 23andMe Research Team, Lake J, Solsberg CW, Leonard H, Makarious MB, Tan EK, Singleton AB, Bandres-Ciga S, Noyce AJ, Global Parkinson’s Genetics Program, Blauwendraat C, Nalls MA, Foo JN, Mata I.
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Multi-ancestry genome-wide association meta-analysis of Parkinson's disease
PubMed.28 December 2023.
Neurology
Richmond RC, Howe LJ, Heilbron K
et al.Show more authors.
Richmond RC, Howe LJ, Heilbron K, Jones S, Liu J, 23andMe Research Team, Wang X, Weedon MN, Rutter MK, Lawlor DA, Davey-Smith G, Vetter C
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Correlations in sleeping patterns and circadian preference between spouses
Communication Biology.13 November 2023.
Behavior
Malawsky DS, Walree EV, Jacobs BM
et al.Show more authors.
Malawsky DS, Walree EV, Jacobs BM, Heng TH, Huang QQ, Sabir AH, Rahman S, Sharif SM, Khan A, Mirkov MU, 23andMe Research Team, Genes & Health Research Team, Kuwahara H, Gao X, Alkuraya FS, Posthuma D, Newman WG, Griffiths CJ, Mathur R, Heel DAV, Martin HC
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Influence of autozygosity on common disease risk across the phenotypic spectrum
Cell.12 October 2023.
Methods
Budu-Aggrey A, Kilanowski A, Sobczyk MK
et al.Show more authors.
Budu-Aggrey A, Kilanowski A, Sobczyk MK, 23andMe Research Team, Shringarpure SS, Mitchell R, Reis K, Reigo A, Estonian Biobank Research Team, Magi R, Nelis M, Tanaka N, Brumpton BM, Thomas LF, Sole-Navais P, Flatley C, Espuela-Ortiz A, Herrera-Luis E, Lominchar JVT, Bork-Jensen J, Marenholz I, Arnau-Soler A, Jeong A, Fawcett KA, Paternoster L
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European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation
Nature Communications.04 October 2023.
Dermatology
Rizig M, Bandres-Ciga S, Makarious MB
et al.Show more authors.
Rizig M, Bandres-Ciga S, Makarious MB, Omolara O, Crea PW, Abiodun OV, Levine KS, Abubakar SA, Achoru CO, Vitale D, Adeniji OA, Agabi OP, Koretsky MJ, Agulanna U, Hall DA, Akinyemi RO,Xie T, Ali MW, Shamim EA, Ani-Osheku I, Padmanaban M, Arigbodi OM, Standaert DG, Bello AH, Dean MN, Erameh CO, Elsayed I, Farombi TH, Okunoye O, Fawale MB, Billingsley KJ, Imarhiagbe FA, Jerez PA, Iwuozo EU, Baker B, Komolafe MA, Malik L, Nwani PO, Daida K, Nwazor EO, Miano-Burkhardt A, Nyandaiti YW, Fang Z, Obiabo YO, Kluss JH, Odeniyi OA, Hernandez DG, Odiase FE, Tayebi N, Ojini FI, Sidranksy E, Onwuegbuzie GA, D’Souza A, Osaigbovo GO, Berhe B, Osemwegie N, Reed X, Oshinaike OO, Leonard HL, Otubogun FM, Alvarado CX, Oyakhire SI, Ozomma SI, Samuel SC, Taiwo FT, Wahab KW, Zubair YA, Iwaki H, Kim JJ, Morris HR, Hardy J, Nalls MA, Heilbron K, Norcliffe-Kaufmann L, Nigeria Parkinson Disease Research Network, International Parkinson’s Disease Genomic Consortium Africa, Black and African American Connections to Parkinson's Disease Study Group, 23andMe Research Team, Blauwendraat C, Houlden H, Singleton A, Okubadejo NU, Global Parkinson’s Genetics Program
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Identification of genetic risk loci and causal insights associated with Parkinson's disease in African and African admixed populations: a genome-wide association study
The Lancet.23 August 2023.
Neurology
Harney E, Micheletti S, Bruwelheide KS
et al.Show more authors.
Harney E, Micheletti S, Bruwelheide KS, Freyman WA, Bryc K, Akbari A, Jewett E, Comer E, Gates Jr. HL, Heywood L, THornton J, Curry R, Esselmann SA, Barca KG, Sedig J, Sirak K, Olalde I, Adamski N, Bernardos R, Broomandkhoshbacht N, Ferry M, Qiu L, Stewardson K, Workman JN, Zalzala F, Mallick S, Micco A, Mah M, Zhang Z, 23andMe Research Team, Rohland N, Mountain J, Owsley DW, Reich D
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The genetic legacy of African Americans from Catoctin Furnace
Science.04 August 2023.
Ancestry
Schootemeijer S, Coker D, Shelton JF
et al.Show more authors.
Schootemeijer S, Coker D, Shelton JF, Chanoff E, Rowbotham HM, Darweesh SKL, 23andMe Research Team, Bloem BR, Cannon P, de Vries NM
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Exercise knowledge, barriers and motivators among LRRK2 G2019S mutation carriers
Parkinsonism & Related Disorders.11 July 2023.
Neurology
Han X, Gharahkhani P, Hamel AR
et al.Show more authors.
Han X, Gharahkhani P, Hamel AR, Ong JS,Rentería ME, Mehta P, Dong X, Pasutto F, Hammond C, Young TL, Hysi P, Lotery AJ, Jorgenson E, Choquet H, Hauser M, Bailey JNC, Nakazawa T, Masato Akiyama, Yukihiro Shiga, Fuller ZL, Wang X, Hewitt AW, Craig JE, Pasquale LR, Mackey DA, Wiggs JL, Khawaja AP, Segrè AV, 23andMe Research Team, International Glaucoma Genetics Consortium, MacGregor S
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Large-scale multitrait genome-wide association analyses identify hundreds of glaucoma risk loci
Nature Genetics.29 June 2023.
Musculoskeletal
Pairo-Castineira E, Rawlik K, Bretherick AD
et al.Show more authors.
Pairo-Castineira E, Rawlik K, Bretherick AD, Qi T, Wu Y, Nassiri I, McConkey GA, Zechner M, Klaric L, Griffiths F, Oosthuyzen W, Kousathanas A, Richmond A, Millar J, Russell CD, Malinauskas T, Thwaites R, Morrice K, Keating S, Maslove D, Nichol A, Semple MG, Knight J, Shankar-Hari M, Summers C, Hinds C, Horby P, Ling L, McAuley D, Montgomery H, Openshaw PJM, Begg C, Walsh T, Tenesa A, Flores C, Riancho JA, Rojas-Martinez A, Lapunzina P, GenOMICC Investigators, SCOURGE Consortium, ISARICC Investigators, The 23andMe COVID-19 Team, Yang J, Ponting CP, Wilson JF, Vitart V, Abedalthagafi M, Luchessi AD, Parra EJ, Cruz R, Carracedo A, Fawkes A, Murphy L, Rowan K, Pereira AC, Law A, Fairfax B, Hendry SC, Baillie JK
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GWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19
Nature.17 May 2023.
Infectious Diseases
Sanchez-Roige S, Jennings MV, Thorpe HHA
et al.Show more authors.
Sanchez-Roige S, Jennings MV, Thorpe HHA, Mallari JE, van der Werf LC, Bianchi SB, Huang Y, Lee C, Mallard TT, Barnes SA, Wu JY, Barkley-Levenson AM, Boussaty EC, Snethlage CE, Schafer D, Babic Z, Winters BD, Watters KE, Biederer T, 23andMe Research Team, Mackillop J, Stephens DN, Elson SE, Fontanillas P, Jibran Y. Khokhar, Jared W. Young JW, Palmer AA
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CADM2 is implicated in impulsive personality and numerous other traits by genome- and phenome-wide association studies in humans and mice
Translational Psychiatry.12 May 2023.
Behavior
Rahmioglu N, Mortlock S, Ghiasi M
et al.Show more authors.
Rahmioglu N, Mortlock S, Ghiasi M, Møller PL, Stefansdottir L, Galarneau G, Turman C, Danning R, Law MH, Sapkota Y, Christofidou P, Skarp S, Giri A, Banasik K, Krassowski M, Lepamets M, Marciniak B, Nõukas M, Perro D, Sliz E, Sobalska-Kwapis M, Thorleifsson G, Topbas-Selcuki NF, Vitonis A, Westergaard D, Arnadottir R, Burgdorf KS, Campbell A, Cheuk CSK, Clementi C, Cook J, De Vivo I, DiVasta A, Dorien O, Donoghue JF, Edwards T, Fontanillas P, Fung JN, Geirsson RT, Girling JE, Harkki P, Harris HR, Healey M, Heikinheimo O, Holdsworth-Carson S, Hostettler IC, Houlden H, Houshdaran S, Irwin JC, Jarvelin M, Kamatani Y, Kennedy SH, Kepka E, Kettunen J, Kubo M, Kulig B, Kurra V, Laivuori H, Laufer MR, Lindgren CM, MacGregor S, Mangino M, Martin NG, Matalliotaki C, Matalliotakis M, Murray AD, Ndungu A, Nezhat C, Olsen CM, Opoku-Anane J, Padmanabhan S, Paranjpe M, Peters M, Polak G, Porteous DJ, Rabban J, Rexrode KM, Romanowicz H, Saare M, Saavalainen L, Schork AJ, Sen S, Shafrir AL, Siewierska-Grska A, Słomka M, Smith BH, Smolarz B, Szaflik T, Szyłło K, Takahashi A, Terry KL, Tomassetti C, Treloar SA, Vanhie A, Vincent K, Vo KC, Werring DJ, Zeggini E, Zervou MI, DBDS Genomic Consortium, FinnGen Study, FinnGen Endometriosis Taskforce, The Celmatix Research Team, The 23andMe Research Team, Adachi S, Buring JE, Ridker PM, D’Hooghe T, Goulielmos GN, Hapangama DK, Hayward C, Horne AW, Low S, Martikainen H, Chasman DI, Rogers PAW, Saunders PT, Sirota M, Spector T, Strapagiel D, Tung JY, Whiteman DC, Giudice LC, Velez-Edwards DR, Uimari O, Kraft P, Salumets A, Nyholt DR, Mägi R, Stefansson K, Becker CM, Yurttas-Beim P, Steinthorsdottir V, Nyegaard M, Missmer SA, Montgomery GW, Morris AP, Zondervan KT
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The genetic basis of endometriosis and comorbidity with other pain and inflammatory conditions
Nature Genetics.13 March 2023.
Reproduction
Saunders GRB, Wang X, Chen F
et al.Show more authors.
Saunders GRB, Wang X, Chen F, Jang S, Liu M, Wang C, Gao S, Jiang Y, Khunsriraksakul C, Otto JM, Addison C, Akiyama M, Albert CM, Aliev F, Alonso A, Arnett DK, Ashley-Koch AE, Ashrani AA, Barnes KC, Barr RG, Bartz TM, Becker DM, Bielak LF, Benjamin EJ, Bis JC, Bjornsdottir G, Blangero J, Bleecker ER, Boardman JD, Boerwinkle E, Boomsma DI, Boorgula MP, Bowden DW, Brody JA, Cade BE, Chasman DI, Chavan S, Chen YI, Chen Z, Cheng I, Cho MH, Choquet H, Cole JW, Cornelis MC, Cucca F, Curran JE, de Andrade M, Dick DM, Docherty AR, Duggirala R, Eaton CB, Ehringer MA, Esko T, Faul JD, Silva LF, Fiorillo E, Fornage M, Freedman BI, Gabrielsen ME, Garrett ME, Gharib SA, Gieger C, Gillespie N, Glahn DC, Gordon SD, Gu CC, Gu D, Gudbjartsson DF, Guo X, Haessler J, Hall ME, Haller T, Harris KM, He J, Herd P, Hewitt JK, Hickie I, Hidalgo B, Hokanson JE, Hopfer C, Hottenga J, Hou L, Huang H, Hung Y, Hunter DJ, Hveem K, Hwang S, Hwu C, Iacono W, Irvin MR, Jee YH, Johnson EO, Joo YY, Jorgenson E, Justice AE, Kamatani Y, Kaplan RC, Kaprio J, Sharon L. R. Kardia, Keller MC, Kelly TN, Kooperberg C, Korhonen T, Kraft P, Krauter K, Kuusisto J, Laakso M, Lasky-Su J, Lee W, Lee JJ, Levy D, Li L, Li K, Li Y, Lin K, Lind PA, Liu C, Lloyd-Jones DM, Lutz SM, Ma J, Mägi R, Manichaikul A, Martin NG, Mathur R, Matoba N, McArdle PF, McGue M, McQueen MB, Medl SE, Metspalu e, Meyers DA, Millwood IY, Mitchell BD, Mohlke KL, Moll M, Montasser ME, Morrison AC, Mulas A, Nielsen JB, North KE, Oelsner EC, Okada Y, Orr V, Palmer ND, Palviainen T, Pit A, Park SL, Peters U, Peters A, Peyser PA, Tinca J. C. Polderman, Rafaels N, Redline S, Reed RM, Reiner AP, Rice JP, Rich SS, Richmond NE, Roan C, Rotter JI, Rueschman MN, Runarsdottir V, Saccone NL, Schwartz DA, Shadyab AH, Shi J, Shringarpure SS, Sicinski K, Skogholt AH, Smith JA, Smith NL, Sotoodehnia N, Stallings MC, Stefansson H, Stefansson K, Stitzel JA, Sun X, Syed M, Tal-Singer R, Taylor AE, Taylor KD, Telen MJ, Thai KK, Tiwari H, Turman C, Tyrfingsson T, Wall TL, Walters RG, Weir DR, Weiss ST, White WB, Whitfield JB, Wiggins KL, Willemsen G, Willer CJ, Winsvold BS, Xu H, Yanek LR, Yin J, Young KL, Young KA, Yu B, Zhao W, Zhou W, Zölner S, Zuccolo L, 23andMe Research Team, The Biobank Japan Project, Batini C, Bergen eW, Bierut LJ, David SP, Sarah A. Gagliano Taliun, Hancock DB, Jiang B, Munaf MR, Thorgeirsson TE, Liu DJ, Vrieze S
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Data related to Genetic diversity fuels gene discovery for tobacco and alcohol use
Nature.07 December 2022.
Behavior
Krohn L, Heilbron K, Blauwendraat C
et al.Show more authors.
Krohn L, Heilbron K, Blauwendraat C, Reynolds RH, Yu E, Senkevich K, Rudakou U, Estiar MA, Gustavsson EK, Brolin K, Ruskey JA, Freeman K, Asayesh F, Chia R, Arnulf I, Michele T. M. Hu, Montplaisir JY, Gagnon J, Desautels A, Dauvilliers Y, Gigli GL, Valente M, Janes F, Bernardini A, Högl B, Stefani A, Ibrahim A, Sonka K, Kemlink D, Oertel W, Janzen A, Plazzi G, Biscarini F, Antelmi E, Figorilli M, Puligheddu M, Mollenhauer B, Trenkwalder C, Sixel-Döing F, Valrie Cochen De Cock, Monaca CC, Heidbreder A, Ferini-Strambi L, Dijkstra F, Viaene M, Abril B, Boeve BF, 23andMe Research Team, Scholz SW, Ryten M, Bres-Ciga S, Noyce A, Cannon P, Pihlstrom L, Nalls MA, Singleton AB, Rouleau GA, Postuma RB, Gan-Or Z
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Genome-wide association study of REM sleep behavior disorder identifies polygenic risk and brain expression effects
Nature Communications.05 December 2022.
Neurology
Doust C, Fontanillas P, Eising E
et al.Show more authors.
Doust C, Fontanillas P, Eising E, Gordon SD, Wang Z, Alagöz G, Molz B, 23andMe Research Team, Quantitative Trait Working Group of the GenLang Consortium, St Pourcain B, Francks C, Marioni RE, Zhao J, Paracchini S, Talcott JB, Monaco AP, Stein JF, Gruen JR, Olson RK, Willcutt EG, DeFries JC, Pennington BF, Smith SD, Wright MJ, Martin NG, Auton A, Bates TC, Fisher SE, Luciano M
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“Discovery of 42 genome-wide significant loci associated with dyslexia ”
Nature Genetics.20 October 2022.
Traits
Yengo L, Vedantam S, Marouli E
et al.Show more authors.
Yengo L, Vedantam S, Marouli E, Sidorenko J, Bartell E, Sakaue S, Graff M, Eliasen rU, Jiang Y, Raghavan S, Miao J, Arias JD, Graham SE, Mukamel RE, Spracklen CN, Yin X, Chen S, Ferreira T, Highl HH, Ji Y, Karaderi T, Lin K, Lül K, Malden DE, Medina-Gomez C, Machado M, Moore A, Rüger S, Sim X, Vrieze S, Ahluwalia TS, Akiyama M, Allison MA, Alvarez M, Andersen MK, Ani A, Appadurai V, Arbeeva L, Bhaskar S, Bielak LF, Bollepalli S, Bonnycastle LL, Bork-Jensen J, Bradfield JP, Bradford Y, Braund PS, Brody JA, Burgdorf KS, Cade BE, Cai H, Cai Q, Campbell A, Caadas-Garre M, Catamo E, Chai J, Chai X, Chang L, Chang Y, Chen C, Chesi A, Choi SH, Chung R, Cocca M, Concas MP, Couture C, Cuellar-Partida G, Danning R, Daw EW, Degenhard F, Delgado GE, Delitala A, Demirkan A, Deng X, Devineni P, Dietl A, Dimitriou M, Dimitrov L, Dorajoo R, Ekici AB, Engmann JE, Fairhurst-Hunter Z, Farmaki A, Faul JD, Fernez-Lopez J, Forer L, Francescatto M, Freitag-Wolf S, Fuchsberger C, Galesloot TE, Gao Y, Gao Z, Geller F, Giannakopoulou O, Giulianini F, Gjesing AP, Goel A, Gordon SD, Gorski M, Grove J, Guo X, Gustafsson S, Haessler J, Hansen TF, Havulinna AS, Haworth SJ, He J, Heard-Costa N, Hebbar P, Hindy G, Ho YA, Hofer E, Holliday E, Horn K, Hornsby WE, Hottenga J, Huang H, Huang J, Huerta-Chagoya A, Huffman JE, Hung Y, Huo S, Hwang MY, Iha H, Ikeda DD, Isono M, Jackson AU, Jäer S, Jansen IE, Johansson I, Jonas JB, Jonsson A, Jrgensen T, Kalafati I, Kanai M, Kanoni S, Krhus LL, Kasturiratne A, Katsuya T, Kawaguchi T, Kember RL, Kentistou KA, Kim H, Kim YJ, Kleber ME, Knol MJ, Kurbasic A, Lauzon M, Le P, Lea R, Lee J, Leonard HL, Li SA, Li X, Li X, Liang J, Lin H, Lin S, Liu J, Liu X, Lo KS, Long J, Lores-Motta L, Luan J, Lyssenko V, Lyytikänen L, Mahajan A, Mamakou V, Mangino M, Manichaikul A, Marten J, Mattheisen M, Mavarani L, McDaid AF, Meidtner K, Melendez TL, Mercader JM, Milaneschi Y, Miller JE, Millwood IY, Mishra PP, Mitchell RE, Mllehave LT, Morgan A, Mucha S, Munz M, Nakatochi M, Nelson CP, Nether M, Nho CW, Nielsen AA, Nolte IM, Nongmaithem SS, Noordam R, Ntalla I, Nutile T, Pit A, Christofidou P, Päna K, Pauper M, Eva R. B. Petersen, Petersen LV, Pitkäen N, Polaek O, Poveda A, Preuss MH, Pyarajan S, Raffield LM, Rakugi H, Ramirez J, Rasheed A, Raven D, Rayner NW, Riveros C, Rohde R, Ruggiero D, Ruotsalainen SE, Ryan KA, Sabater-Lleal M, Saxena R, Scholz M, Sendamarai A, Shen B, Shi J, Shin JH, Sidore C, Sitlani CM, Slieker RC, Roelof A. J. Smit, Smith AV, Smith JA, Smyth LJ, Southam L, Steinthorsdottir V, Sun L, Takeuchi F, Divya Sri Priyanka Tallapragada, Taylor KD, Tayo BO, Tchejieu C, Terzikhan N, Tesolin P, Teumer A, Theusch E, Thompson DJ, Thorleifsson G, Timmers PRHJ, Trompet S, Turman C, Vaccargiu S, van der Laan SW, van der Most PJ, van Klinken JB, van Setten J, Verma SS, Verweij N, Veturi Y, Wang CA, Wang C, Wang L, Wang Z, Warren HR, Wei WB, Wickremasinghe AR, Wielscher M, Wiggins KL, Winsvold BS, Wong e, Wu Y, Wuttke M, Xia R, Xie T, Yamamoto K, Yang J, Yao J, Young H, Yousri NA, Yu L, Zeng L, Zhang W, Zhang X, Zhao J, Zhao W, Zhou W, Zimmermann ME, Zoledziewska M, Adair LS, Hieab H. H. 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Cancer
Johnson EC, Demontis D, Thorgeirsson TE
et al.Show more authors.
Johnson EC, Demontis D, Thorgeirsson TE, Walters RK, Polimanti R, Hatoum AS, Sanchez-Roige S, Paul SE, Wendt FR, Clarke TK, Lai D, Reginsson GW, Zhou H, He J, Baranger DAA, Gudbjartsson DF, Wedow R, Adkins DE, Adkins AE, Alexander J, Bacanu SA, Bigdeli TB, Boden J, Brown SA, Bucholz KK, Bybjerg-Grauholm J, Corley RP, Degenhardt L, Dick DM, Domingue BW, Fox L, Goate AM, Gordon SD, Hack LM, Hancock DB, Hartz SM, Hickie IB, Hougaard DM, Krauter K, Lind PA, McClintick JN, McQueen MB, Meyers JL, Montgomery GW, Mors O, Mortensen PB, Nordentoft M, Pearson JF, Peterson RE, Reynolds MD, Rice JP, Runarsdottir V, Saccone NL, Sherva R, Silberg JL, Tarter RE, Tyrfingsson T, Wall TL, Webb BT, Werge T, Wetherill L, Wright MJ, Zellers S, Adams MJ, Bierut LJ, Boardman JD, Copeland WE, Farrer LA, Foroud TM, Gillespie NA, Grucza RA, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono WG, Johnson EO, Kendler KS, Kennedy MA, Kranzler HR, Madden PA, Maes HH, Maher BS, Martin NG, McGue M, McIntosh AM, Medland SE, Nelson EC, Porjesz B, Riley BP, Stallings MC, Vanyukov MM, Vrieze S, Psychiatric Genomics Consortium Substance Use Disorders Workgroup, Davis LK, Bogdan R, Gelernter J, Edenberg HJ, Stefansson K, Børglum AD, Agrawal A.
Show fewer authors.
A large-scale genome-wide association study meta-analysis of cannabis use disorder
The Lancet Psychiatry.20 October 2020.
Behavior
Bao EL, Nandakumar SK, Liao X
et al.Show more authors.
Bao EL, Nandakumar SK, Liao X, Bick AG, Karjalainen J, Tabaka M, Gan OI, Havulinna AS, Kiiskinen TTJ, Lareau CA, de Lapuente Portilla AL, Li B, Emdin C, Codd V, Nelson CP, Walker CJ, Churchhouse C, de la Chapelle A, Klein DE, Nilsson B, Wilson PWF, Cho K, Pyarajan S, Gaziano JM, Samani NJ, FinnGen, 23andMe Research Team, Regev A, Palotie A, Neale BM, Dick JE, Natarajan P, O’Donnell CJ, Daly MJ, Milyavsky M, Kathiresan S, Sankaran VG.
Show fewer authors.
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells
Nature.14 October 2020.
Cancer
Krebs K, Bovijn J, Zheng N
et al.Show more authors.
Krebs K, Bovijn J, Zheng N, Lepamets M, Censin JC, Jürgenson T, Särg D, Abner E, Laisk T, Luo Y, Skotte L, Geller F, Feenstra B, Wang W, Auton A, 23andMe Research Team, Agee M, Aslibekyan S, Bell RK, Bryc K, Clark SK, Elson SL, Fletez-Brant K, Fontanillas P, Furlotte NA, Gandhi PM, Heilbron K, Hicks B, Hinds DA, Huber KE, Jewett EM, Jiang Y, Kleinman A, Lin KH, Litterman NK, Luff MK, McCreight JC, McIntyre MH, McManus KF, Mountain JL, Mozaffari SV, Nandakumar P, Noblin ES, Northover CAM, O’Connell J, Petrakovitz AA, Pitts SJ, Poznik GD, Sathirapongsasuti JF, Shastri AJ, Shelton JF, Shringarpure S, Tian C, Tung JY, Tunney RJ, Vacic V, Wang X, Zare AS, Raychaudhuri S, Esko T, Metspalu A, Laur S, Roden DM, Wei WQ, Holmes MV, Lindgren CM, Phillips EJ, Mägi R, Milani L, Fadista J
Show fewer authors.
Genome-wide Study Identifies Association between HLA-B∗55:01 and Self-Reported Penicillin Allergy
Science Direct.01 October 2020.
Immunity
Williams DM, Bandres‐Ciga S, Heilbron K et al.Show more authors. Williams DM, Bandres‐Ciga S, Heilbron K, Hinds D, Noyce AJ, The 23andMe Research Team, The International Parkinson's Disease Genomics Consortium. Show fewer authors.“Evaluating lipid-lowering drug targets for Parkinson's disease prevention”Annals of Neurology.25 August 2020.
Neurology
Choi KW, Stein MB, Nishimi KM et al.Show more authors.Choi KW, Stein MB, Nishimi KM, Ge T, Coleman JRI, Chen C, Ratanatharathorn A, Zheutlin AB, Dunn EC, 23andMe Research Team, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Breen G, Koenen KC, Smoller JW. Show fewer authors.“A two-stage approach to identifying and validating modifiable factors for the prevention of depression”American Journal of Psychiatry.14 August 2020.
Psychiatry
Micheletti SJ, Bryc K, Ancona Esselmann SG et al.Show more authors.Micheletti SJ, Bryc K, Ancona Esselmann SG, Freyman WA, Moreno ME, Poznik D, Shastri AJ, 23andMe Research Team. Show fewer authors.“Genetic Consequences of the Transatlantic Slave Trade in the Americas”AJHG.
06 August 2020.
ELSI
Schneider RB, Myers TL, Rowbotham HM et al.Show more authors. Schneider RB, Myers TL, Rowbotham HM, Luff MK, Amodeo K, Sharma S, Wilson R, Jensen-Roberts S, Auinger P, McDermott MP, Alcalay RN, Biglan K, Kinel D, Tanner C, Winter-Evans R, Augustine EF, Cannon P, 23andMe Research Team, Holloway RG, Dorsey ER. Show fewer authors.“A virtual cohort study of individuals at genetic risk for Parkinson’s disease: study protocol and design”Journal of PD.28 July 2020.
Neurology
Brumpton B, Sanderson E, Heilbron K et al.Show more authors.Brumpton B, Sanderson E, Heilbron K, Hartwig FP, Harrison S, Åberge Vie G, Cho Y, Howe LD, Hughes A, Boomsma DI, Havdahl A, Hopper J, Neale M, Nivard MG, Pedersen NL, Reynolds CA, Tucker-Drob EM, Grotzinger A, Howe L, Morris T, Li S, The Within-family Consortium, The 23andMe Research Team, Auton A, Windmeijer F, Chen W, Bjørngaard JH, Hveem K, Willer C, Evans DM, Kaprio J, Smith GD, Åsvold BO, Hemani G & Davies NM. Show fewer authors.“Within-family studies for Mendelian randomization: avoiding dynastic, assortative mating, and population stratification biases”14 July 2020.
Methods
Guo J, Rist PM, Daghlas I et al.Show more authors. Guo Y, Rist PM, Daghlas I, Giulianini F, The International Headache Genetics Consortium, The 23andMe Research Team, Kurth T, Chasman DI. Show fewer authors.“Genetic basis for blood pressure associations with migraine”Nature Communications.06 July 2020.
Neurology
Ferreira MAR, Vonk JM, Baurecht H et al.Show more authors.Ferreira MAR, Vonk JM, Baurecht H, Marenholz I, Tian C, Hoffman JD, Helmer Q, Tillander A, Ullemar V, Lu Y, Grosche S, Rüschendorf F, Granell R, Brumpton BM, Fritsche LG, Bhatta L, Gabrielsen ME, Nielsen JB, Zhou W, Hveem K, Langhammer A, Holmen OL, Løset M, Abecasis GR, Willer CJ, Emami NC, Cavazos TB, Witte JS, Szwajda A, the 23andMe Research Team, collaborators of the SHARE study, Hinds DA, Hübner N, Weidinger S, Magnusson PKE, Jorgenson E, Karlsson R, Paternoster L, Boomsma DI, Almqvist C, Lee Y, Koppelman GH. Show fewer authors.“Age-of-onset information helps identify 76 genetic variants associated with allergic disease”PLOS Genetics.30 June 2020.
Immunity
Whiffin N, Armean I, Kleinman A et al.Show more authors. Whiffin N, Armean IM, Kleinman A, Marshall JL, Minikel EV, Goodrich JK, Quaife NM, Cole JB, Wang Q, Karczewski KJ, Cummings BB, Francioli L, Laricchia K, Guan A, Alipanahi B, Morrison P, Baptista MAS, Merchant KM, Genome Aggregation Database Production Team, Genome Aggregation Database Consortium, Ware JS, Havulinna AS, Iliadou B, Lee J, Nadkarni GN, Whiteman C, 23andMe Research Team, Daly M, Esko T, Hultman C, Loos RJF, Milani L, Palotie A, Pato C, Pato M, Saleheen D, Sullivan PF, Alföldi J, Cannon C, MacArthur DG. Show fewer authors.“The effect of LRRK2 loss-of-function variants in humans”Nature.01 June 2020.
Neurology
Rudakou U, Futhey NC, Krohn L et al.Show more authors. Rudakou U, Futhey NC, Krohn L, Ruskey JA, Heilbron K, Cannon P, The 23andMe Research Team, Alam A, Arnulf I, Hu MTM, Montplaisir JY, Gagnon J, Desautels A, Dauvilliers Y, Toffoli M, Gigli GL, Valente M, Högl B, Stefani A, Holzknecht E, Sonka K, Kemlink D, Oertel W, Janzen A, Plazzi G, Antelmi E, Figorilli M, Puligheddu M, Mollenhauer B, Trenkwalder C, Sixel-Döring F, De Cock VC, Monaca CC, Heidbreder A, Ferini-Strambi L, Dijkstra F, Viaene M, Abril B, Boeve BF, Postuma RB, Rouleau GA, Gan-Or Z. Show fewer authors.“SMPD1 variants do not have a major role in rapid eye movement sleep behavior disorder”Neurobiology of Aging.18 April 2020.
Neurology
Rovira P, Demontis D, Sánchez-Mora C et al.Show more authors.Rovira P, Demontis D, Sánchez-Mora C, Zayats T, Klein M, Mota NR, Weber H, Garcia-Martínez I, Pagerols M, Vilar-Ribó L, Arribas L, Richarte V, Corrales M, Fadeuilhe C, Bosch R, Martin GE, Almos P, Doyle AE, Grevet EH, Grimm O, Halmøy A, Hoogman M, Hutz M, Jacob CP, Kittel-Schneider S, Knappskog PM, Lundervold AJ, Rivero O, Rovaris DL, Salatino-Oliveira A, da Silva BS, Svirin E, Sprooten E, Strekalova T, ADHD Working Group of the Psychiatric Genomics Consortium, 23andMe Research team, Arias-Vasquez A, Sonuga-Barke EJS, Asherson P, Dotto Bau CH, Buitelaar JK, Cormand B, Faraone SV, Haavik J, Johansson SE, Kuntsi J, Larsson H, Lesch K, Reif A, Rohde LA, Casas M, Børglum AD, Franke B, Ramos-Quiroga JA, Artigas MS, Ribasés M. Show fewer authors.“Shared genetic background between children and adults with attention deficit/hyperactivity disorder”Neuropsychopharmacology.
12 April 2020.
Psychiatry
Adewuyi EO, Sapkota Y, International Endogene Consortium et al.Show more authors.Adewuyi EO, Sapkota Y, International Endogene Consortium, 23andMe Research Team, International Headache Genetics Consortium, Auta A, Yoshihara K, Nyegaard M, Griffiths LR, Montgomery GW, Chasman DI, Nyholt DR. Show fewer authors.“Shared Molecular Genetic Mechanisms Underlie Endometriosis and Migraine Comorbidity.”Genes.29 February 2020.
Reproduction
Krohn L, Wu RYJ, Heilbron K et al.Show more authors.Krohn L, Wu RYJ, Heilbron K, Ruskey JA, Laurent SB, Blauwendraat C, Alam A, Arnulf I, Hu MTM, Dauvilliers Y, Högl B, Toft M, Bjørnarå KA, Stefani A, Holzknecht E, Monaca CC, Abril B, Plazzi G, Antelmi E, Ferini-Strambi L, Young P, Heidbreder A, Cochen De Cock V, Mollenhauer B, Sixel-Döring F, Trenkwalder C, Sonka K, Kemlink D, Figorilli M, Puligheddu M, Dijkstra F, Viaene M, Oertel W, Toffoli M, Gigli GL, Valente M, Gagnon JF, Nalls MA, Singleton AB; 23andMe Research Team, Desautels A, Montplaisir JY, Cannon P, Ross OA, Boeve BF, Dupré N, Fon EA, Postuma RB, Pihlstrøm L, Rouleau GA, Gan-Or Z. Show fewer authors.“Fine-Mapping of SNCA in Rapid Eye Movement Sleep Behavior Disorder and Overt Synucleinopathies”Annals of Neurology.24 January 2020.
Neurology
Boutin TS, Charteris DG, Chandra A et al.Show more authors.Boutin TS, Charteris DG, Chandra A, Campbell S, Hayward C, Campbell A; UK Biobank Eye & Vision Consortium, Nandakumar P, Hinds D; 23andMe Research Team, Mitry D, Vitart V. Show fewer authors.“Insights into the genetic basis of retinal detachment”Human Molecular Genetics.09 December 2019.
Traits
Dennis J, Sealock J, Levinson RT et al.Show more authors.Dennis J, Sealock J, Levinson RT, Farber-Eger E, Franco J, Fong S, Straub P, Hucks D, Song WL, Linton MF, Fontanillas P, Elson SL, Ruderfer D, Abdellaoui A, Sanchez-Roige S, Palmer AA, Boomsma DI, Cox NJ, Chen G, Mosley JD, Wells QS, Davis LK. Show fewer authors.“Genetic risk for major depressive disorder and loneliness in sex-specific associations with coronary artery disease”Molecular Psychiatry.03 December 2019.
Behavior
Nalls MA, Blauwendraat C, Vallerga CL et al.Show more authors.Nalls MA, Blauwendraat C, Vallerga CL, Heilbron K, Bandres-Ciga S, Chang D, Tan M, Kia DA, Noyce AJ, Xue A, Bras J, Young E1, von Coelln R, Simón-Sánchez J, Schulte C, Sharma M, Krohn L, Pihlstrøm L, Siitonen A, Iwaki H, Leonard H, Faghri F, Gibbs JR, Hernandez DG, Scholz SW, Botia JA, Martinez M, Corvol JC, Lesage S, Jankovic J, Shulman LM, Sutherland M, Tienari P, Majamaa K, Toft M, Andreassen OA, Bangale T, Brice A, Yang J, Gan-Or Z, Gasser T, Heutink P, Shulman JM, Wood NW, Hinds DA, Hardy JA, Morris HR, Gratten J, Visscher PM, Graham RR, Singleton AB; 23andMe Research Team; System Genomics of Parkinson's Disease Consortium; International Parkinson's Disease Genomics Consortium. Show fewer authors.“Identification of novel risk loci, causal insights, and heritable risk for Parkinson’s disease: a meta-analysis of genome-wide association studies.”The Lancet Neurology.01 December 2019.
Neurology
Blauwendraat C, Reed X, Krohn L et al.Show more authors.Blauwendraat C, Reed X, Krohn L, Heilbron K, Bandres-Ciga S, Tan M, Gibbs JR, Hernandez DG, Kumaran R, Langston R, Bonet-Ponce L, Alcalay RN, Hassin-Baer S, Greenbaum L, Iwaki H, Leonard HL, Grenn FP, Ruskey JA, Sabir M, Ahmed S, Makarious MB, Pihlstrøm L, Toft M, van Hilten JJ, Marinus J, Schulte C, Brockmann K, Sharma M, Siitonen A, Majamaa K, Eerola-Rautio J, Tienari PJ; 23andMe Research Team, Pantelyat A, Hillis AE, Dawson TM, Rosenthal LS, Albert MS, Resnick SM, Ferrucci L, Morris CM, Pletnikova O, Troncoso J, Grosset D, Lesage S, Corvol JC, Brice A, Noyce AJ, Masliah E, Wood N, Hardy J, Shulman LM, Jankovic J, Shulman JM, Heutink P, Gasser T, Cannon P, Scholz SW, Morris H, Cookson MR, Nalls MA, Gan-Or Z, Singleton AB. Show fewer authors.“Genetic modifiers of risk and age at onset in GBA associated Parkinson’s disease and Lewy body dementia”Brain.22 November 2019.
Neurology
Abdellaoui A, Sanchez-Roige S, Sealock J et al.Show more authors.Abdellaoui A, Sanchez-Roige S, Sealock J, Treur JL, Dennis J, Fontanillas P, Elson S; 23andme Research Team, Nivard MG, Ip HF, van der Zee M, Baselmans BML, Hottenga JJ, Willemsen G, Mosing M, Lu Y, Pedersen NL, Denys D, Amin N, M van Duijn C, Szilagyi I, Tiemeier H, Neumann A, Verweij KJH, Cacioppo S, Cacioppo JT, Davis LK, Palmer AA, Boomsma DI. Show fewer authors.“Phenome-wide investigation of health outcomes associated with genetic predisposition to loneliness.”Human Molecular Genetics.15 November 2019.
Behavior
Noyce AJ, Bandres-Ciga S, Kim J et al.Show more authors.Noyce AJ, Bandres-Ciga S, Kim J, Heilbron K, Kia D, Hemani G, Xue A, Lawlor DA, Smith GD, Duran R, Gan-Or Z, Blauwendraat C, Gibbs JR; 23andMe Research Team, International Parkinson's Disease Genomics Consortium (IPDGC), Hinds DA, Yang J, Visscher P, Cuzick J, Morris H, Hardy J, Wood NW, Nalls MA, Singleton AB. Show fewer authors.“The Parkinson’s Disease Mendelian Randomization Research Portal”Movement Disorders.28 October 2019.
Neurology
Gallagher CS, Mäkinen N, Harris HR et al.Show more authors.Gallagher CS, Mäkinen N, Harris HR, Rahmioglu N, Uimari O, Cook JP, Shigesi N, Ferreira T, Velez-Edwards DR, Edwards TL, Mortlock S, Ruhioglu Z, Day F, Becker CM, Karhunen V, Martikainen H, Järvelin MR, Cantor RM, Ridker PM, Terry KL, Buring JE, Gordon SD, Medland SE, Montgomery GW, Nyholt DR, Hinds DA, Tung JY; 23andMe Research Team, Perry JRB, Lind PA, Painter JN, Martin NG, Morris AP, Chasman DI, Missmer SA, Zondervan KT, Morton CC. Show fewer authors.“Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis”Nature Communications.24 October 2019.
Reproduction
Thompson DJ, Genovese G, Halvardson J et al.Show more authors.Thompson DJ, Genovese G, Halvardson J, Ulirsch JC, Wright DJ, Terao C, Davidsson OB, Day FR, Sulem P, Jiang Y, Danielsson M, Davies H, Dennis J, Dunlop MG, Easton DF, Fisher VA, Zink F, Houlston RS, Ingelsson M, Kar S, Kerrison ND, Kristjansson RP, Li R, Loveday C, Mattisson J, McCarroll SA, Murakami Y, Murray A, Olszewski P, Rychlicka-Buniowska E, Scott RA, Thorsteinsdottir U, Tomlinson I, Moghadam BT, Turnbull C, Wareham NJ, Gudbjartsson DF, INTEGRAL-ILCCO, The Breast Cancer Association Consortium, CIMBA, The Endometrial Cancer Association Consortium, The Ovarian Cancer Association Consortium, The PRACTICAL Consortium, The Kidney Cancer GWAS Meta-Analysis Project, eQTLGen Consortium, BIOS Consortium, 23andMe Research Team, Kamatani Y, Finucane HK, Hoffmann ER, Jackson SP, Stefansson K, Auton A, Ong KK, Machiela MJ, Loh P, Dumanski JP, Chanock SJ, Forsberg LA, Perry JRB. Show fewer authors.“Genetic predisposition to mosaic Y chromosome loss in blood”Nature.20 October 2019.
Methods
Ganna A, Verweij KJH, Nivard MG et al.Show more authors.Ganna A, Verweij KJH, Nivard MG, Maier R, Wedow R, Day FR, Busch AS, Abdellaoui A, Guo S, Sathirapongsasuti JF, 23andMe Research Team, Lichtenstein P, Lunström S, Långström N, Auton A, Harris KM, Beecham GW, Martin ER, Sanders AR, Perry JRB, Neale BM, Zietsch BP. Show fewer authors.“Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior”Science.30 August 2019.
Traits
Brandon N, Sern O, Huiwen L et al.Show more authors.Brandon N, Sern O, Huiwen L, Peh JH, Roger ML, Giles Graham, Gao Chi , Kraft Peter, John Esther M, Swerdlow Anthony, Brenner Hermann, Wu Anna H, Christopher HD, Gareth E, Wei Z, Peter FA, Esteban CJ, Ava K, Xia S, Kamila C, Per H, Alison D, Douglas E, Mikael H, Jingmei L. Show fewer authors.“The genetic interplay between body mass index, breast size and breast cancer risk: A Mendelian randomization analysis”International Journal of Epidemiology.21 July 2019.
Cancer
Warrington NM, Beaumont RN, Horikoshi M et al.Show more authors.Warrington NM, Beaumont RN, Horikoshi M, Day FR, Helgeland Øyvind, Laurin C, Bacelis J, Peng S, Hao K, Feenstra B, Wood AR, Mahajan A, Tyrrell J, Robertson NR, Rayner WN, Qiao Z, Moen G, Vaudel M, Marsit CJ, Chen J, Nodzenski M, Schnurr TM, Zafarmand MH, Bradfield JP, Grarup N, Kooijman MN, Li-Gao R, Geller F, Ahluwalia TS, Paternoster L, Rueedi R, Huikari V, Hottenga J, Lyytikäinen L, Cavadino A, Metrustry S, Cousminer DL, Wu Y, Thiering E, Wang CA, Have CT, Vilor-Tejedor N, Joshi PK, Painter JN, Ntalla I, Myhre R, Pitkänen N, van Leeuwen EM, Joro R, Lagou V, Richmond RC, Espinosa A, Barton SJ, Inskip HM, Holloway JW, Santa-Marina L, Estivill X, Ang W, Marsh JA, Reichetzeder C, Marullo L, Hocher B, Lunetta KL, Murabito JM, Relton CL, Kogevinas M, Chatzi L, Allard C, Bouchard L, Hivert M, Zhang G, Muglia LJ, Heikkinen J, EGG Consortium, Morgen CS, van Kampen AHC, van Schaik BDC, Mentch FD, Langenberg C, Luan J, Robert A. Scott RA, Jing Hua Zhao JH, Gibran Hemani G, Susan M. Ring SM, Amanda J. Bennett AJ, Kyle J. Gaulton KJ, Fernandez-Tajes J, van Zuydam NR, Medina-Gomez C, de Haan HG, Rosendaal FR, Kutalik Z, Marques-Vidal P, Das S, Willemsen G, Mbarek H, Müller-Nurasyid M, Standl M, Appel EVR, Fonvig CE, Trier C, van Beijsterveldt CEM, Murcia M, Bustamante M, Bonas-Guarch S, Hougaard DM, Mercader JM, Linneberg A, Schraut KE, Lind PA, Medland SE, Shields BM, Knight BA, Chai J, Panoutsopoulou K, Bartels M, Sánchez F, Stokholm J, Torrents D, Vinding RK, Willems SM, Atalay M, Chawes BL, Kovacs P, Prokopenko I, Tuke MA, Yaghootkar H, Ruth KS, Jones SE, Loh P, Murray A, Weedon MN, Tönjes A, Stumvoll M, Michaelsen KF, Eloranta A, Lakka TA, van Duijn CM, Kiess W, Körner A, Niinikoski H, Pahkala K, Raitakari OT, Jacobsson B, Zeggini E, Dedoussis GV, Teo Y, Saw S, Montgomery GW, Campbell H, Wilson JF, Vrijkotte TGM, Vrijheid M, de Geus EJCN, Hayes GM, Kadarmideen HN, Holm J, Beilin LJ, Pennell CE, Heinrich J, Adair LS, Borja JB, Mohlke KL, Eriksson JG, Widén EE, Hattersley AT, Spector TD, Kähönen M, Viikari JS, Lehtimäki T, Boomsma DI, Sebert S, Vollenweider P, Sørensen TIA, Bisgaard H, Bønnelykke K, Murray JC, Melbye M, Nohr EA, Mook-Kanamori DO, Rivadeneira F, Hofman A, Felix JF, Jaddoe VWV, Hansen T, Pisinger C, Vaag AA, Pedersen O, Uitterlinden A, Järvelin M, Power C, Hyppönen E, Scholtens DM, Lowe Jr WL, Smith GD, Timpson NJ, Morris AP, Wareham NJ, Hakonarson H, Grant SFA, Frayling TM, Lawlor DA, Njølstad PR, Johansson S, Ong KK, McCarthy MI, Perry JRB, Evans DM, Freathy RM. Show fewer authors.“Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic disease”Nature Genetics.01 May 2019.
Reproduction
Blauwendraat C, Heilbron K, Vallerga CL et al.Show more authors.Blauwendraat C, Heilbron K, Vallerga CL, Bandres-Ciga S, Rainer von C, Pihlstrøm L, Simón-Sánchez J, Schulte C, Sharma M, Krohn L, Siitonen A, Iwaki H, Hampton L, Noyce AJ, Tan M, Gibbs RJ, Hernandez DG, Scholz SW, Jankovic J, Shulman LM, Lesage S, Corvol J, Brice A, van Hilten JJ, Marinus J, The 23andMe Research Team, Tienari P, Majamaa K, Toft M, Grosset DG, Gasser T, Heutink P, Shulman JM, Wood N, Hardy J, Morris HR, Hinds DA, Gratten J, Visscher PM, Gan-Or Z, Nalls MA, Singleton AB, for the International Parkinson’s Disease Genomics Consortium (IPDGC). Show fewer authors.“Parkinson’s disease age of onset: defining heritability, identifying genetic loci, implicating α-synuclein mechanisms”Movement Disorders.07 April 2019.
[bioRxiv]
Neurology
Ferreira MAR, Mathur R, Vonk JM et al.Show more authors.Ferreira MAR, Mathur R, Vonk JM, Szwajda A, Brumpton B, Granell R, Brew BK, Ullemar V, Lu Y, Jiang Y, 23andMe Research Team, eQTLGen Consortium, BIOS Consortium, Magnusson PK.E, Karlsson R, Hinds DA, Paternoster L, Koppelman GH, Almqvist C. Show fewer authors.“Genetic risk factors for childhood- and adult-onset asthma are partly distinct”American Journal of Human Genetics.04 April 2019.
Immunity
Warrier V, Toro R, Won H et al.Show more authors.Warrier V, Toro R, Won H, Leblond CS, Cliquet F, Delorme R, De Witte W, Bralten J, Chakrabarti B, Børglum AD, Grove J, Poelmans G, Hinds DA, Bourgeron T, Baron-Cohen S. Show fewer authors.“Social and non-social autism symptoms and trait domains are genetically dissociable”Communications Biology.09 March 2019.
Behavior
Jakob G, Stephan R, Thomas AD et al.Show more authors.Jakob G, Stephan R, Thomas AD, Manuel M, Raymond W, Hyejung W, Jonatan P, Esben A, Ole AA, Richard A, Belliveau R, Bettella F, Buxbaum JD, Bybjerg-Grauholm J, Bækved-Hansen M, Cerrato F, Chambert K, Christensen JH, Churchhouse C, Dellenvall K, Demontis D, De Rubeis S, Devlin B, Djurovic S, Dumont A, Goldstein J, Hansen CS , Hauberg ME, Hollegaard MV, Hope S, Howrigan DP, Huang H, Hultman C, Klei L, Maller J, Martin J, Martin AR, Moran J, Nyegaard M, Nærland T, Palmer DS, Palotie A , Pedersen CB, Pedersen MG, Poterba T, Poulsen JB, St Pourcain B, Qvist P, Rehnström K, Reichenberg A, Reichert J, Robinson EB, Roeder K, Roussos P, Saemundsen E, Sandin S, Satterstrom FK, Smith GD, Stefansson H, Stefansson K, Steinberg S, Stevens C, Sullivan PF, Turley P, Walters GB, Xu X, Autism Spectrum Disorders Working Group of The Psychiatric Genomics Consortium, BUPGEN, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 23andMe Research Team, Geschwind D, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Neale BM, Daly MJ, Børglum AD. Show fewer authors.“Common risk variants identified in autism spectrum disorder”Nature Genetics.25 February 2019.
[bioRxiv]
Neurology
Howard DM, Adams MJ, Clarke T et al.Show more authors.Howard DM, Adams MJ, Clarke T, Hafferty JD, Gibson J, Shirali M, Coleman JRI, Hagenaars SP, Ward J, Wigmore EM, Alloza C, Shen X, Barbu MC, Xu EY, Whalley HC, Marioni RE, Porteous DJ, Davies G, Deary IJ, Hemani G, Berger K, Teismann H, Rawal R, Arolt V, Baune BT, Dannlowski U, Domschke K, Tian C, Hinds DA, 23andMe Research Team, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Trzaskowski M, Byren EM, Ripke S, Smith DJ, Sullivan PF, Wray NR, Breen G, Lewis CM, McIntosh AM. Show fewer authors.“Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.”Nature Neuroscience.04 February 2019.
Psychiatry
Jones SE, Lane JM, Wood AR et al.Show more authors.Jones SE, Lane JM, Wood AR, van Hees VT, Tyrrell J, Beaumont RN, Jeffries AR, Dashti HS, Hillsdon M, Ruth KS, Tuke MA, Yaghootkar H, Sharp SA, Jie Y, Thompson WD, Harrison JW, Dawes A, Byren EM, Tiemeier H, Allebrandt KV, Bowden J, Ray DW, Freathy RM, Murray A, Mazzotti DR, Gehrman PR, Lawlor DA, Frayling TM, Rutter MK, Hinds DA, Saxena R, Weedon, MN. Show fewer authors.“Genome-wide association analyses of chronotype in 697,828 individuals provides new insights into circadian rhythms in humans and links to disease.”Nature Communications.29 January 2019.
Neurology
Liu M, Jiang Y, Wedow R et al.Show more authors.Liu M, Jiang Y, Wedow R, Li Y, Brazel DM, Chen F, Datta G, Davila-Velderrain J, McGuire D, Tian C, Zhan X, 23andMe Research Team, HUNT All-In Psychiatry, Choquet H, Docherty AR, Faul JD, Foerster JR, Fristche LG, Gabrielsen ME, Gordon SD, Haessler J, Hottenga J, Huang H, Jang S, Jansen PR, Ling Y, Mägi R, Matoba N, McMahon G, Mulas A, Orrù V, Palviainen T, Pandit A, Reginsson GW, Skogholt AH, Smith JA, Taylor AE, Turman C, Willemsen G, Young H, Young KA, Zajac GJM, Zhao W, Zhou W, Bjornsdottir G, Boardman JD, Boehnke M, Boomsma DI, Chen C, Cucca F, Davies GE, Eaton CB, Ehringer MA, Esko T, Fiorillo E, Gillespie NA, Gudbjartsson DF, Haller T, Harris KM, Heath AC, Hewitt JK, Hickie IB, Hokanson JE, Hopfer CJ, Hunger DJ, Iacono WG, Johnson EO, Kamatani Y, Kardia SLR, Keller MC, Kellis M, Kooperberg C, Kraft P, Krauter KS, Laakso M, Lind PA, Luokola A, Lutz SM, Madden PAF, Martin NG, McGue M, McQueen MB, Medland SE, Metspalu A, Mohlke KL, Nielsen JB, Okada Y, Peters U, Polderman TJC, Posthuma D, Reiner AP, Rice JP, Rimm E, Rose RJ, Runarsdottir V, Stallings MC, Stančáková, Stegansson H, Thai KK, Tindle HA, Tyrfingsson T, Wall TL, Weir DR, Weisner C, Whitfield JB, Winsvold BS, Yin J, Zuccolo L, Bierut LJ, Hveem K, Lee JJ, Munafò, Sccone NL, Willer CJ, Corenlis MC, David SP, Hinds DA, Jorgenson E, Kaprio J, Stitzel JA, Stefansson K, Thorgeirsson TE, Abecasis G, Liu DJ, Vrieze S. Show fewer authors.“Association studies of up to 1.2 million individuals yield new insights in the genetic etiology of tobacco and alcohol use.”Nature Genetics.14 January 2019.
Behavior
Linnér RK, Biroli P, Kong E et al.Show more authors.Linnér RK, Biroli P, Kong E, Meddens SFW, Wedow R, Fontana MA, Lebreton M, Abdellaoui A, Hammerschlag AR, Nivard MG, Okbay A, Rietveld CA, Timshel PN, Tino SP, Trzaskowski M, de Vlaming R, Zünd CL, Bao Y, Buzdugan L, Caplin AH, Chen C, Eibich P, Fontanillas P, Gonzalez JR, Joshi PK, Karhunen V, Kleinman A, Levin RZ, Lill CM, Meddens GA, Muntané G, Sanchez-Roige S, van Rooij FJ, Taskesen E, Wu Y, Zhang F, 23andMe Research Team, eQTLgen Consortium, International Cannabis Consortium, Psychiatric Genomics Consortium, Social Science Genetic Association Consortium, Auton A, Boardman JD, Clark DW, Conlin A, Dolan CC, Fischbacher U, Groenen PJF, Harris KM, Hasler G, Hofman A, Ikram M, Jain S, Karlsson R, Kessler R, Kooyman M, MacKillop J, Männikkö M, Morcillo-Suarez C, McQueen MB, Schmidt KM, Smart MC, Sutter M, Thurik AR, Uitterlinden AG, White J, de Wit H, Yang J, Bertram L, Boomsma D, Esko T, Fehr E, Hinds DA, Johannesson M, Kumari M, Laibson D, Magnusson PKE, Meyer MN, Navarro A, Palmer AA, Pers TH, Posthuma D, Schunk D, Stein MB, Svento R, Tiemeier H, Timmers PRHJ, Turley P, Ursano RJ, Wagner GG, Wilson JF, Gratten J, Lee JJ, Cesarini D, Benjamin DJ, Koellinger P, Beauchamp JP. Show fewer authors.“GWAS of risk tolerance and risky behaviors in over one million individuals identify hundreds of loci and reveal shared genetic influences.”Nature Genetics.14 January 2019.
Behavior
Day F, Karaderi T, Jones MR et al.Show more authors.Day F, Karaderi T, Jones MR, Meun C, He C, Drong A, Kraft P, Lin N, Huang H, Broer L, Magi R, Saxena R, Laisk T, Urbanek M, Hayes MG, Thorleitfsson G, Fernandez-Tajes J, Mahajan A, Mullin BH, Stuckey MGA, Spector TD, Wilson SG, Goodarzi MO, Davis L, Obermayer-Pietsch B, Uitterlinden AG, Anttila V, Neale BM, Jarvelin M, Fauser B, Kowalska I, Visser JA, Andersen M, Ong K, Stener-Victorin E, Ehrmann D, Legro RS, Salumets A, McCarthy MI, Morin-Papunen L, Thorsteinsdottir U, Stegansson K, the 23andMe Research Team, Styrkarsdottir U, Perry JRB, Dunaif A, Laven K, Franks S, Lindgren CM, Welt CK. Show fewer authors.“Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria.”PLoS Genetics.19 December 2018.
Reproduction
Demontis D, Walters RK, Martin J et al.Show more authors.Demontis D, Walters RK, Martin J, Mattheisen M, Als TD, Agerbo E, Baldursson G, Belliveau R, Bybjerg-Grauholm J, Bækvad-Hansen M, Cerrato F, Chambert K, Churchhouse C, Dumont A, Eriksson N, Gandal M, Goldstein JI, Grasby KL, Grove J, Gudmundsson OO, Hansen CS, Hauberg ME, Hollegaard MV, Howrigan DP, Huang H, Maller JB, Martin AR, Martin NG, Moran J, Pallesen J, Palmer DS, Pedersen CB, Pedersen MG, Poterba T, Poulsen JB, Ripke S, Robinson E, Satterstrom FK, Stegansson H, Stevens C, Turley P, Walters GB, Won H, Wright MJ, ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium, 23andMe Research Team, Andreassen OE, Asherson P, Burton CL, Boomsma DI, Cormand B, Dalsgaard S, franke B, Gelernter J, Geschwind D, Hakonarson H, Haavik J, Kranzler HR, Kuntsi J, Langley K, Lesch K, Middeldorp C, Reif A, Rohde LA, Roussos P, Schachar R, Sklar P, Sonuga-Barke EJS, Sullivan PF, Thapar A, Tung JY, Waldman ID, Medland SE, Stefansson K, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Daly MJ, Faraone SV, Børglum AD, Neale BM. Show fewer authors.“Discovery of the first genome-wide significant risk loci for ADHD.”Nature Genetics.26 November 2018.
Psychiatry
Walters RK, Adams MJ, Adkins AE et al.Show more authors.Walters RK, Adams MJ, Adkins AE, Aliev F, Bacanu S, Batzler A, Bertelsen S, Biernacka J, Bigdeli TB, Chen L, Clark T, Chou Y, Degenhardt F, Docherty AR, Fontanillas P, Foo J, Fox L, Frank J, Giegling I, Gordon S, Hack L, Hartz S, Heilmann-Heimbach S, Herms S, Hodgkinson C, Hoffmann P, Hottenga J, Kennedy MA, Alanne-Kinnunen M, Knote B, Lahti J, Lahti-Pulkkinen M, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Milaneschi Y, Palviainen T, Pearson J, Peterson R, Polimanti R, Ripatti S, Ryu E, Saccone N, Salvatore J, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang J, Webb BT, Wedow R, Wetherill L, Wills AG, 23andMe Research Team, Boardman J, Chen D, Choi D, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Elson SL, Frye M, Gäbel W, Ising M, Johnson EC, Keyes M, Kiefer F, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Männistö, McClintick JN, Meyers JL, Müller-Myhsok B, Nurnberger JI, Palotie A, Preuss U, Räikkönen K, Reynolds MD, Ridinger M, Scherbaum N, Shuckit M, Soyka M, Treutlein J, Witt S, Wodarz N, Zill P, Adkins D, Boden JM, Boomsma D, Bierut LJ, Brown SA, Bucholz KK, Chicho S, Costello EJ, de Wit H, Diazgranados N, Dick DM, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AA, Goldman D, Grucza RA, Hancock DB, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer C, Horwood J, Iacono W, Johnson EO, Kaprio JA, Karpyak V, Kendler KS, Kranzler HR, Krauter K, Lichtenstein P, Lind PA, McGue M, MacKillop J, Madden PAF, Maes H, Magnusson P, Martin NG, Medland SE, Montgomery GW, Nelson EC, Nöthen M, Palmer AA, Pedersen NL, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose R, Rujescu D, Shen P, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Gelernter J, Edenberg HJ, Agrawal A. Show fewer authors.“Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.”Nature Neuroscience.26 November 2018.
Behavior
Orlova E, Yeh A, Shi M et al.Show more authors.Orlova E, Yeh A, Shi M, Firek B, Ranganathan S, 23andMe Research Team, Whitcomb DC, Finegold DN, Ferrel RE, Barmada MM, Marazita ML, Hinds DA, Shaffer JR, Morowitz MJ. Show fewer authors.“Genetic association and differential expression of PITX2 with acute appendicitis.”Human Genetics.03 November 2018.
Immunity
Sanchez-Roige S, Palmer AA, Fontanillas P et al.Show more authors.Sanchez-Roige S, Palmer AA, Fontanillas P, Elson S, 23andMe Research Team, Substance Use Disorder Working Group of the Psychiatric Genomics Consortium, Adams MJ, Howard DM, Edenberg HJ, Davies G, Crist RC, Deary I, McIntosh AM, Clarke TK. Show fewer authors.“Meta-analysis GWAS of the Alcohol Use Disorder Identification Test (AUDIT) in two population based cohorts (N=141,958).”American Journal of Psychiatry.19 October 2018.
[bioRxiv]
Behavior
Psychiatry
Diogo D, Tian C, Franklin C et al.Show more authors.Diogo D, Tian C, Franklin C, Alanne-Kinnunen M, March M, Spencer C, Vangjeli C, Weale M, Mattsson H, Elina K, Sleiman P, Reilly D, McElwee J, Maranville J, Chatterjee A, Bhandari A, 23andMe Research Team, Reeve M, Hutz J, Bing N, John S, MacArthur D, Salomaa V, Ripatti S, Hakonarson H, Daly M, Palotie A, Hinds D, Donnelly P, Fox C, Day-Williams A, Plenge R, Runz H. Show fewer authors.“Phenome-wide association studies across large ‘real-world data’ population cohorts support drug target validation.”Nature Communications.16 October 2018.
Methods
Pasman JA, Verweij KJH, Gerring Z et al.Show more authors.Pasman JA, Verweij KJH, Gerring Z, Stringer S, Sanchez-Roige S, Treur JL, Abdellaoui A, Nivard MG, Baselmans BML, Ong J, Ip HF, van der Zee MD, Bartels M, Day JF, Fontanillas P, Elson SL, the 23andMe Research Team, de Wit H, Davis LK, MacKillop J, International Cannabis Consortium, Derringer JL, Branje SJT, Hartman CA, Heath AC, van Lier PAC, Madden PAF, Magi R, Meeus W, Montgomery GW, Oldehinkel AJ, Pausova Z, Ramos-Quiroga JA, Paus T, Ribases M, Kaprio J, Boks MPM, Bell JT, Spector TD, Gelernter J, Boomsma DI, Martin NG, MacGregor S, Perry JRB, Palmer AA, Posthuma D, Manuafo MR, Gillespie NA, Derks EM, Vink JM. Show fewer authors.“GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia.”Nature Neuroscience.27 August 2018.
Behavior
Jones HJ, Heron J, Hammerton G et al.Show more authors.Jones HJ, Heron J, Hammerton G, Stochl J, Jones PB, Cannon M, Smith GD, Holmans P, Lewis G, Linden DEJ, O'Donovan MC, Owen MJ, Walters J, Zammit S, 23andMe Research Team. Show fewer authors.“Investigating the genetic architecture of general and specific psychopathology in adolescence.”Translational Psychiatry.08 August 2018.
Psychiatry
Lee JJ, Wedow RW, Okbay AO et al.Show more authors.Lee JJ, Wedow RW, Okbay AO, Kong EK, Maghzian OM, Zacher MZ, Nguyen-Viet TA, Bowers PB, Sidorenko JS, Linnér RK, Fontana MA, Kundu TK, Lee CL, Li HL, Li RL, Royer RR, Timshel PN, Walters RK, Willoughby EA, Yengo LY, 23andMe Research Team, COGENT (Cognitive Genomics Consortium), Social Science Genetic Association Consortium, Alver MA, Bao YB, Clark DW, Day FR, Furlotte NA, Joshi PK, Kemper KE, Kleinman AK, Langenberg CL, Mägi RM, Trampush JW, Verma SS, Wu YW, Lam ML, Zhao JH, Zheng ZZ, Boardman JD, Campbell HC, Freese JF, Harris KM, Hayward CH, Herd PH, Kumari MK, Lencz TL, Luan JL, Malhotra AK, Metspalu AM, Milani LM, Ong KK, Perry JRB, Porteous DJ, Ritchie MD, Smart MC, Smith BH, Tung JY, Wareham NJ, Wilson JF, Beauchamp JP, Conley DC, Esko TE, Lehrer SF, Magnusson PKE, Oskarsson SO, Pers TH, Robinson MR, Thom KT, Watson CW, Chabris CF, Meyer MN, Laibson DI, Yang JY, Johannesson MJ, Koellinger PD, Turley PT, Visscher PM, Benjamin DJ, Cesarini DC. Show fewer authors.“Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.”Nature Genetics.23 July 2018.
Behavior
Waage J, Standl M, Curtin JA et al.Show more authors.Waage J, Standl M, Curtin JA, Jessen LE, Thorsen J, Tian C, Schoettler N, The 23andMe Research Team, AAGC collaborators, Flores C, Abdellaoui A, Ahluwalia TS, Alves AC, Amaral AFS, Antó JM, Arnold A, Barreto-Luis A, Baurecht H, van Beijsterveldt CEM, Bleecker ER, Bonàs-Guarch Boomsma DI, Brix S, Bunyavanich S, Burchard EG, Chen Z, Curjuric I, Custovic A, den Dekker HT, Dharmage SC, Dmitrieva J, Duijts L, Ege MJ, Gauderman WJ, Georges M, Gieger C, Gilliland F, Granell R, Gui H, Hansen T, Heinrich J, Henderson J, Hernandez-Pacheco N, Holt P, Imboden M, VWV Jaddoe, Jarvelin MR, Jarvis DL, Jensen KK, Jónsdóttir I, Kabesch M, Kaprio J, Kumar A, Lee, YALevin AM, Li X, Lorenzo-Diaz F, Melén E, Mercader JM, Meyers DA, Myers R, Nicolae DL, Nohr EA, Palviainen T, Paternoster L, Pennell CE, Pershagen G, Pino-Yanes M, Probst-Hensch NM, Rüschendorf F, Simpson A, Stefansson K, Sunyer J, Sveinbjornsson G, Thiering E, T hompson PJ, Torrent M, Torrents D, Tung JY, Wang CA, Weidinger S, Weiss S, Willemsen G, Williams LK, Ober C, Hinds DA, Ferreira MA, Bisgaard H, Strachan DP, Bønnelykke K. Show fewer authors.“Genome-wide association and HLA fine mapping studies identify risk loci and genetic pathways of allergic rhinitis.”Nature Genetics.16 July 2018.
Immunity
Huusko JM, Karjalainen MK, Graham BE et al.Show more authors.Huusko JM, Karjalainen MK, Graham BE, Zhang G, Farrow EG, Miller NA, Jacobsson B, Eidem HR, Murray JC, Bedell BB, Breheny PB, Brown NW, Bødker FL, Litterman NK, Jiang P, Russell L, Hinds DA, Hu Y, The 23andMe Research Team, Rokas A, Teramo K, Christensen KC, Williams SM, Rämet M, Kingsmore SF, Ryckman KK, Hallman M, Muglia LJ. Show fewer authors.“Whole exome sequencing reveals HSPA1L as a genetic risk factor for spontaneous preterm birth.”PLoS Genetics.12 July 2018.
Reproduction
Nagel M, Jansen PR, Stringer S et al.Show more authors.Nagel M, Jansen PR, Stringer S, Watanabe K, de Leeuw CA, Bryois J, Savage JE, Hammerschlag AR, Skene NG, Muñoz-Manchado AB, Agee M, Alipanahi B, Auton A, Bell RK, Bryc K, Elson SL, Fontanillas P, Furlotte NA, Hinds DA, Hromatka BS, Huber KE, Kleinman A, Litterman NK, McIntyre MH, Mountain JL, Noblin ES, Mountain JL, Northover CAM, Pitts SJ, Sathirapongsasuti JF, Sazonova OV, Shelton JF, Shringarpure S, Tian C, Tung JY, Vacic V, Wilson CH, White T, Tiemeier H, Linnarsson S, Hjerling-Leffler J, Polderman TJC, Sullivan PF, van der Sluis S, Posthuma D. Show fewer authors.“Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.”Nature Genetics.25 June 2018.
Behavior
Tedja MS, Wojciechowski R, Hysi PG et al.Show more authors.Tedja MS, Wojciechowski R, Hysi PG, Eriksson N, Furlotte NA, Verhoeven VJM, Iglesias AI, Meester-Smoor MA, Tompson SW, Fan Q, Khawaja AP, Cheng C, Höhn R, Yamashiro K, Wenocur A, Grazal C, Haller T, Metspalu A, Wedenoja J, Jonas JB, Wang YX, Xie J, Mitchell P, Foster PJ, Klein BEK, Klein R, Paterson AD, Hosseini SM, Shah RL, Williams C, Teo YY, Tham YC, Gupta P, Zhao W, Shi Y, Saw W, Tai E, Sim XL, Huffman JE, Polašek O, Hayward C, Bencic G, Rudan I, Wilson JF, The CREAM Consortium, 23andMe Research Team, UK Biobank Eye and Vision Consortium, Joshi PK, Tsujikawa A, Matsuda F, Whisenhunt KN, Zeller T, van der Spek PJ, Haak R, Meijers-Heijboer H, van Leeuwen EM, Iyengar SK, Lass JH, Hofman A, Rivadeneira F, Uitterlinden AG, Vingerling JR, Lehtimäki T, Raitakari OT, Biino G, Pina Concas M, Schwantes-An T, Igo Jr RP, Cuellar-Partida G, Martin NG, Craig JE, Gharahkhani P, Williams KM, Nag A, Rahi JS, Cumberland PM, Delcourt C, Bellenguez C, Ried JS, Bergen AA, Meitinger T, Gieger C, Wong TY, Hewitt AW, Mackey DA, Simpson CL, Pfeiffer N, Pärssinen O, Baird PN, Vitart V, Amin N, van Duijn CM, Bailey-Wilson JE, Young TL, Saw S, Stambolian D, MacGregor S, Guggenheim JA, Tung JY, Hammond CJ, Klaver CCW. Show fewer authors.“Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error.”Nature Genetics.28 May 2018.
Traits
Anttila V, Bulik-Sullivan B, Finucane HK et al.Show more authors.Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu2 D, Lee PH, Turley P, Grenier-Boley B, Chouraki V, Kamatani Y, Berr C, Letenneur L, Hannequin D, Amouyel P, Boland A, Deleuze J, Duron E, Vardarajan BN, Reitz C, Goate AM, Huentelman MJ, Kamboh MI, Larson EB, Rogaeva E, George-Hyslop PS, Hakonarson H, Kukull WA, Farrer LA, Barnes LL, Beach TG, Demirci FY, Head E, Hulette CM, Jicha GA, Kauwe JS, Kaye JA, Leverenz JB, Levey AI, Lieberman AP, Pankratz VS, Poon WW, Quinn JF, Saykin AJ, Schneider LS, Smith AG, Sonnen JA, Stern RA, Van Deerlin VM, Van Eldik LJ, Harold D, Russo G, Rubinsztein DC, Bayer A, Tsolaki M, Proitsi P, Fox NC, Hampel H, Owen MJ, Mead S, Passmore P, Morgan K, Nöthen MM, Rossor M, Lupton MK, Hoffmann P, Kornhuber J, Lawlor B, McQuillin A, Al-Chalabi99 A, Bis JC, Ruiz A, Boada M, Seshadri S, Beiser A, Rice K, van der Lee SJ, De Jager PL, Geschwind DH, Riemenschneider M, Riedel-Heller S, Rotter JI, Ransmayr G, Hyman BT, Cruchaga C, Alegret M, Winsvold B, Palta P, Farh K, Cuenca-Leon E, Furlotte N, Kurth T, Ligthart L, Terwindt GM, Freilinger T, Ran C, Gordon SD, Borck G, Adams HH, Lehtimäki T, Wedenoja J, Buring JE, Schürks M, Hrafnsdottir M, Hottenga J, Penninx B, Artto V, Kaunisto M, Vepsäläinen S, Martin NG, Montgomery GW, Kurki MI, Hämäläinen E, Huang H, Huang J, Sandor C, Webber C, Muller-Myhsok B, Schreiber S, Salomaa V, Loehrer E, Göbel H, Macaya A, Pozo-Rosich P, Hansen T, Werge T, Kaprio J, Metspalu A, Kubisch C, Ferrari MD, Belin AC, van den Maagdenberg AMJM, Zwart J, Boomsma D, Eriksson N, Olesen J, Chasman DI, Nyholt DR, Avbersek A, Baum L, Berkovic S, Bradfield J, Buono R, Catarino CB, Cossette P, Jonghe PD, Depondt C, Dlugos D, Ferraro TN, French J, Hjalgrim H, Jamnadas-Khoda J, Kälviäinen R, Kunz WS, Lerche H, Leu C, Lindhout D, Lo W, Lowenstein D, McCormack M, Møller RS, Molloy A, Ng P, Oliver K, Privitera M, Radtke R, Ruppert A, Sander T, Schachter S, Schankin C, Scheffer I, Schoch S, Sisodiya SM, Smith P, Sperling M, Striano P, Surges R, Thomas GN, Visscher F, Whelan CD, Zara F, Heinzen EL, Marson A, Becker F, Stroink H, Zimprich F, Gasser T, Gibbs R, Heutink P, Martinez M, Morris HR, Sharma M, Ryten M, Mok KY, Pulit S, Bevan S, Holliday E, Attia J, Battey T, Boncoraglio G, Thijs V, Chen W, Mitchell B, Rothwell P, Sharma P, Sudlow C, Vicente A, Markus H, Kourkoulis C, Pera J, Raffeld M, Silliman S, Perica VB, Thornton LM, Huckins LM, Rayner NW, Lewis CM, Gratacos M, Rybakowski F, Keski-Rahkonen A, Raevuori A, Hudson JI, Reichborn-Kjennerud T, Monteleone P, Karwautz A, Mannik K, Baker JH, O’Toole JK, Trace SE, Davis OSP, Helder SG, Ehrlich S, Herpertz-Dahlmann B, Danner UN, van Elburg AA, Clementi M, Forzan M, Docampo E, Lissowska J, Hauser J, Tortorella A, Maj M, Gonidakis F, Tziouvas K, Papezova H, Yilmaz Z, Wagner G, Cohen-Woods S, Herms S, Julià A, Rabionet R, Dick DM, Ripatti S, Andreassen OA, Espeseth T, Lundervold AJ, Steen VM, Pinto D, Scherer SW, Aschauer H, Schosser A, Alfredsson L, Padyukov L, Halmi KA, Mitchell J, Strober M, Bergen AW, Kaye W, Szatkiewicz JP, Cormand B, Ramos-Quiroga JA, Sánchez-Mora C, Ribasés M, Casas M, Hervas A, Arranz MJ, Haavik J, Zayats T, Johansson S, Williams N, Dempfle A, Rothenberger A, Kuntsi J, Oades RD, Banaschewski T, Franke B, Buitelaar JK, Vasquez AA, Doyle AE, Reif A, Lesch K, Freitag C, Rivero O, Palmason H, Romanos M, Langley K, ietschel M, Witt SH, Dalsgaard S, Børglum AD, Waldman I, Wilmot B, Molly N, Bau CH, Crosbie J, Schachar R, Loo SK, McGough JJ, Grevet EH, Medland SE, Robinson E, Weiss LA, Bacchelli E, Bailey A, Bal V, Battaglia A, Betancur C, Bolton P, Cantor R, Celestino-Soper P, Dawson G, Rubeis SD, Duque F, Green A, Klauck SM, Leboyer M, Levitt P, Maestrini E, Mane S, De-Luca DM, Parr J, Regan R, Reichenberg A, Sandin S, Vorstman J, Wassink T, Wijsman E, Cook E, Santangelo S, Delorme R, Rogé B, Magalhaes T, Arking D, Schulze TG, Thompson RC, Strohmaier J, Matthews K, Melle I, Morris D, Blackwood D, McIntosh A, Bergen SE, Schalling M, Jamain S, Maaser A, Fischer SB, Reinbold CS, Fullerton JM, Guzman-Parra J, Mayoral F, Schofield PR, Cichon S, Mühleisen TW, Degenhardt F, Schumacher J, Bauer M, Mitchell PB, Gershon ES, Rice J, Potash JB, Zandi PP, Craddock N, Ferrier IN, Alda M, Rouleau GA, Turecki G, Ophoff R, Pato C, Anjorin A, Stahl E, Leber M, Czerski PM, Cruceanu C, Jones IR, Posthuma D, Andlauer TF, Forstner AJ, Streit F, Baune BT, Air T, Sinnamon G, Wray NR, MacIntyre DJ, Porteous D, Homuth G, Rivera M, Grove J, Middeldorp CM, Hickie I, Pergadia M, Mehta D, Smit JH, Jansen R, Geus Ed, Dunn E, Li QS, Nauck M, Schoevers RA, Beekman AT, Knowles JA, Viktorin A, Arnold P, Barr CL, Bedoya-Berrio G, Bienvenu OJ, Brentani H, Burton C, Camarena B, Cappi C, Cath D, Cavallini M, Cusi D, Darrow S, Denys D, Derks EM, Dietrich A, Fernandez T, Figee M, Freimer N, Gerber G, Grados M, Greenberg E, Hanna GL, Hartmann A, Hirschtritt ME, Hoekstra PJ, Huang A, Huyser C, Illmann C, Jenike M, Kuperman S, Leventhal B, Lochner C, Lyon GJ, Macciardi F, Madruga-Garrido M, Malaty IA, Maras A, McGrath L, Miguel EC, Mir P, Nestadt G, Nicolini H, Okun MS, Pakstis A, Paschou P, Piacentini J, Pittenger C, Plessen K, Ramensky V, Ramos EM, Reus V, Richter MA, Riddle MA, Robertson MM, Roessner V, Rosário M, Samuels JF, Sandor P, Stein DJ, Tsetsos F, Nieuwerburgh FV, Weatherall S, Wendland JR, Wolanczyk T, Worbe Y, Zai G, Goes FS, McLaughlin N, Nestadt PS, Grabe H, Depienne C, Konkashbaev A, Lanzagorta N, Valencia-Duarte A, Bramon E, Buccola N, Cahn W, Cairns M, Chong SA, Cohen D, Crespo-Facorro B, Crowley J, Davidson M, DeLisi L, Dinan T, Donohoe G, Drapeau E, Duan J, Haan L, Hougaard D, Karachanak-Yankova S, Khrunin A, Klovins J, Kučinskas V, Keong JLC, Limborska S, Loughland C, Lönnqvist J, Maher B, Mattheisen M, McDonald C, Murphy KC, Nenadic I, Os Jv, Pantelis C, Pato M, Petryshen T, Quested D, Roussos P, Sanders AR, Schall U, Schwab SG, Sim K, So H, Stögmann E, Subramaniam M, Toncheva D, Waddington J, Walters J, Weiser M, Cheng W, Cloninger R, Curtis D, Gejman PV, Henskens F, Mattingsdal M, Oh S, Scott R, Webb B, Breen G, Churchhouse C, Bulik CM, Daly M, Dichgans M, Faraone SV, Guerreiro R, Holmans P, Kendler KS, Koeleman B, Mathews CA, Price A, Scharf J, Sklar P, Williams J, Wood NW, Cotsapas C, Palotie A, Smoller JW, Sullivan P, Rosand J, Corvin A, Neale BM. Show fewer authors.“Analysis of shared heritability in common disorders of the brain.”Science.28 May 2018.
Psychiatry
Gormley P, Kurki MI, Eveliina M et al.Show more authors.Gormley P, Kurki MI, Eveliina M, Veerapen K, Happola P, Mitchell AA, Lal D, Palta P, Surakka I, Kaunisto MA, Hamalainen E, Vepsalainen S, Havanka H, Harno H, Ilmavirta M, Nissila M, Sako E, Sumelahti M, Liukkonen J, Sillanpaa M, Metsahonkala L, Koskinen S, Lehtimaki T, Raitakari O, Mannikko M, Ran C, Belin AC, Jousilahti P, Anttila V, Salomaa V, Artto V, Farkkila M, 23andMe Research Team, International Headache Genetics Consortium (IHGC), Runz H, Daly MJ, Neale BM, Ripatti S, Kallela M, Wessman M, Palotie A. Show fewer authors.“Common variant burden contributes to the familial aggregation of migraine in 1,589 families.”Neuron.03 May 2018.
Neurology
Wray NR, Ripke S, Mattheisen M et al.Show more authors.Wray NR, Ripke S, Mattheisen M, Trzaskowski M, Byrne EM, Abdellaoui A, Adams MJ, Agerbo E, Air TM, Andlauer FTM, Bacanu S, Bækvad-Hansen M, Beekman TAF, Bigdeli TB, Binder EB, Blackwood DRH, Bryois J, Buttenschøn HN, Bybjerg-Grauholm J, Cai N, Castelao E, Christensen JH, Clarke T, Coleman RJI, Colodro-Conde L, Couvy-Duchesne B, Craddock N, Crawford GE, Crowley CA, Dashti HS, Davies G, Deary IJ, Degenhardt F, Derks EM, Direk N, Dolan CV, Dunn EC, Eley TC, Eriksson N, Escott-Price V, KiadehFarhadi FH, Finucane HK, Forstner AJ, Frank J, Gaspar HA, Gill M, Giusti-Rodríguez P, Goes FS, Gordon SD, Grove J, Hall LS, Hannon E, Hansen CS, Hansen TF, Herms S, HickieI B, Hoffmann P, Homuth G, Horn C, Hottenga J, Hougaard DM, Hu M, Hyde CL, Ising M, Jansen R, Jin F, Jorgenson E, Knowles JA, Kohane IS, Kraft J, Kretzschmar WW, Krogh J, Kutalik Z, Lane JM, Li Y, Li Y, Lind PA, Liu X, Lu L, MacIntyre DJ, MacKinnon DF, Maier RM, Maier W, Marchini J, Mbarek H, McGrath P, McGuffin P, Medland SE, Mehta D, Middeldorp CM, Mihailov E, Milaneschi E, Milani L, Mill J, Mondimore FM, Montgomery GW, Mostafavi S, Mullins N, Nauck M, Ng B, Nivard MG, Nyholt DR, O’Reilly PF, Oskarsson H, Owen MJ, Painter JN, Pedersen CB, Pedersen MG, Peterson RE, Pettersson E, Peyrot WJ, Pistis G, Posthuma D, Purcell SM, Quiroz JA, Qvist P, Rice JP, Riley BP, Rivera M, Mirza SS, Saxena R, Schoevers R, Schulte EC, Shen L, Shi J, Shyn SI, Sigurdsson E, Sinnamon GBC, Smit JH, Smith DJ, Stefansson H, Steinberg S, Stockmeier CA, Streit F, Strohmaier J, Tansey KE, Teismann H, Teumer A, Thompson W, Thomson PA, Thorgeirsson TE, Tian C, Traylor M, Treutlein J, Trubetskoy V, Uitterlinden AG, Umbricht D, Auwerader SV, Hemertvan AM, Viktorin A, Visscher PM, Wang Y, Webb BT, Weinsheimer SM, Wellmann J, Willemsen G, Witt SH, Wu Y, Xi HS, Yang J, Zhang F, eQTLGen, 23andMe, Arolt V, Baune BT, Berger K, Boomsma DI, Cichon S, Dannlowski U, de Geus ECJ, DePaulo JR, Domenici E, Domschke K, Esko T, Grabe HJ, Hamilton SP, Hayward C, Heath AC, Hinds DA, Kendler KS, Kloiber S, Lewis G, Li QS, Lucae S, Madden PFA, Magnusson PK, Martin NG, McIntosh AM, Metspalu A, Mors O, Mortensen PB, Müller-Myhsok B, Nordentoft M, Nöthen MM, O’Donovan MC, Paciga SA, Pedersen NL, H BWJ, Perlis RH, Porteous DJ, Potash JB, Preisig M, Rietschel M, Schaefer C, Schulze TG, Smoller JW, Stefansson K, Tiemeier H, Uher R, Völzke H, Weissman MM, Werge T, Winslow AR, Lewis CM, Levinson DF, Breen G, Børglum AD, Sullivan PF, The Major Depressive Disorder Working of the Psychiatric Genomics Consortium. Show fewer authors.“Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.”Nature Genetics.26 April 2018.
Psychiatry
Ferreira MAR, Vonk JM, Baurecht H et al.Show more authors.Ferreira MAR, Vonk JM, Baurecht H, Marenholz I, Tian C, Hoffman JD, Helmer Q, Tillander A, Ullemar V, Lu Y, Rüschendor F, 23andMe Research Team, Hinds DA, Hübner N, Weidinger S, Magnusson PKE, Jorgenson E, Lee Y, Boomsma DI, Karlsson R, Almqvist C, Koppelman GH, Paternoster L. Show fewer authors.“Eleven loci with new reproducible genetic associations with allergic disease risk.”Journal of Allergy and Clinical Immunology.19 April 2018.
Immunity
Hysi PG, Valdes AM, Liu F et al.Show more authors.Hysi PG, Valdes AM, Liu F, Furlotte NA, Evans DM, Bataille V, Visconti A, Hemani G, McMahon G, Ring SM, Smith GD, Duffy DL, Zhu G, Gordon SD, Medland SE, Lin BD, Willemsen G, Hottenga JJ, Vuckovic D, Girotto G, Gandin I, Sala C, Concas MP, Brumat M, Gasparini P, Toniolo D, Cocca M, Robino A, Yazar S, Hewitt AW, Chen Y, Zeng C, Uitterlinden AG, Ikram MA, Hamer MA, van Duijn CM, Nijsten T, Mackey DA, Falchi M, Boomsma DI, Martin NG, Hinds DA, Kayser M, Spector TD, The International Visible Trait Genetics Consortium. Show fewer authors.“A GWAS meta-analysis of more than 300,000 individuals of European ancestry identifies numerous new genetic loci explaining significant portions of hair color variation and heritability.”Nature Communications.16 April 2018.
Traits
Howard DM, Adams MJ, Shirali M et al.Show more authors.Howard DM, Adams MJ, Shirali M, Clarke TK, Marioni RE, Davies G, Coleman JRI, Alloza C, Shen X, Barbu MC, Wigmore EM, Gibson J, Agee M, Alipanahi B, Auton A, Bell RK, Bryc K, Elson SL, Fontanillas P, Furlotte NA, Hinds DA, Huber KE, Kleinman A, Litterman NK, McCreight JC, McIntyre MH, Mountain JL, Noblin ES, Northover CAM, Pitts SJ, Sathirapongsasuti JF, Sazonova OV, Shelton JF, Shringarpure S, Tian C, Tung JY, Vacic V, Wilson CH, Hagenaars SP, Lewis CM, Ward J, Smith DJ, Sullivan PF, Haley CS, Breen G, Deary IJ, McIntosh AM. Show fewer authors.“Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways.”Nature Communications.16 April 2018.
Neurology
Psychiatry
Turley P, Walters RK, Maghzian O et al.Show more authors.Turley P, Walters RK, Maghzian O, Okbay A, Lee JJ, Fontana MA, Nguyen-Viet TA, Wedow R, Zacher M, Furlotte NA, Magnusson P, Oskarsson S, Johannesson M, Visscher PM, Laibson D, Cesarini D, Neale BM, Benjamin DJ, 23andMe Research Team, Social Science Genetic Association Consortium. Show fewer authors.“Multi-trait analysis of genome-wide association summary statistics using MTAG.”Nature Genetics.03 January 2018.
Methods
Shaffer JR, Li J, Lee MK et al.Show more authors.Shaffer JR, Li J, Lee MK, Roosenboom J, Orlova E, Adhikari K, Agee M, Alipanahi B, Auton A, Bell RK, Bryc K, Elson SL, Fontanillas P, Furlotte NA, Hromatka BS, Huber KE, Kleinman A, Litterman NK, McIntyre MH, Mountain JL, Noblin ES, Northover CAM, Pitts SJ, Sathirapongsasuti JF, Sazonova OV, Shelton JF, Shringarpure S, Tian C, Tung JY, Vacic V, Wilson CH, Gallo C, Poletti G, Schuler-Faccini L, Bortolini MC, Canizales-Quinteros S, Rothhammer F, Bedoya G, González-José R, Pfeffer PE, Wollenschlaeger CA, Hecht JT, Wehby GL, Moreno LM, Ding A, Jin L, Yang Y, Carlson JC, Leslie EJ, Feingold E, Marazita ML, Hinds DA, Cox TC, Wang S, Ruiz-Linares A, Weinberg SM. Show fewer authors.“Multiethnic GWAS reveals polygenic architecture of earlobe attachment.”American Journal of Human Genetics.30 November 2017.
Traits
Ferreira MA, Vonk JM, Baurecht H et al.Show more authors.Ferreira MA, Vonk JM, Baurecht H, Marenholz I, Tian C, Hoffman JD, Helmer Q, Tillander A, Ullemar V, van Dongen J, Lu Y, Rüschendorf F, Esparza-Gordillo J, Medway CW, Mountjoy E, Burrows K, Hummel O, Grosche S, Brumpton BM, Witte JS, Hottenga JJ, Willemsen G, Zheng J, Rodríguez E, Hotze M, Franke A, Revez JA, Beesley J, Matheson MC, Dharmage SC, Bain LM, Fritsche LG, Gabrielsen ME, Balliu B, 23andMe Research Team, AAGC collaborators, BIOS consortium, LifeLines Cohort Study, Nielsen JB, Zhou W, Hveem K, Langhammer A, Holmen OL, Løset M, Abecasis GR, Willer CJ, Arnold A, Homuth G, Schmidt CO, Thompson PJ, Martin NG, Duffy DL, Novak N, Schulz H, Karrasch S, Gieger C, Strauch K, Melles RB, Hinds DA, Hübner N, Weidinger S, Magnusson PKE, Jansen R, Jorgenson E, Lee YA, Boomsma DI, Almqvist C, Karlsson R, Koppelman GH, Paternoster L. Show fewer authors.“Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.”Nature Genetics.13 October 2017.
Immunity
Schormair B, Zhao C, Bell S et al.Show more authors. Schormair B, Zhao C, Bell S, Tilch E, Salminen AV, Pütz B, Dauvilliers Y, Stefani A, Högl B, Poewe W, Kemlink D, Sonka K, Bachmann CG, Paulus W, Trenkwalder C, Oertel WH, Hornyak M, Teder-Laving M, Metspalu A, Hadjigeorgiou GM, Polo O, Fietze I, Ross OA, Wszolek Z, Butterworth AS, Soranzo N, Ouwehand WH, Roberts DJ, Danesh J, Allen RP, Earley CJ, Ondo WG, Xiong L, Montplaisir J, Gan-Or Z, Perola M, Vodicka P, Dina C, Franke A, Tittmann L, Stewart AFR, Shah SH, Gieger C, Peters A, Rouleau GA, Berger K, Oexle K, Di Angelantonio E, Hinds DA, Müller-Myhsok B, Winkelmann J, 23andMe Research Team, DESIR study group. Show fewer authors.“Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis.”The Lancet: Neurology.13 October 2017.
Neurology
Chang D, Nalls MA, Hallgrímsdóttir IB et al.Show more authors. Chang D, Nalls MA, Hallgrímsdóttir IB, Hunkapiller J, van der Brug M, Cai F, International Parkinson's Disease Genomics Consortium, 23andMe Research Team, Kerchner GA, Ayalon G, Bingol B, Sheng M, Hinds D, Behrens TW, Singleton AB, Bhangale TR, Graham RR. Show fewer authors.“A meta-analysis of genome-wide association studies identifies 17 new Parkinson’s disease risk loci”Nature Genetics.11 September 2017.
Neurology
Zhang G, Feenstra B, Bacelis J et al.Show more authors. Zhang G, Feenstra B, Bacelis J, Liu X, Muglia LM, Juodakis J, Miller DE, Litterman N, Jiang P, Russell L, Hinds DA, Hu Y, Weirauch MT, Chen X, Chavan AR, Wagner GP, Pavličev M, Nnamani MC, Maziarz J, Karjalainen MK, Rämet M, Sengpiel V, Geller F, Boyd HA, Palotie A, Momany A, Bedell B, Ryckman KK, Huusko JM, Forney CR, Kottyan LC, Hallman M, Teramo K, Nohr EA, Smith GD, Melbye M, Jacobsson B, Muglia LJ. Show fewer authors.“Genetic associations with gestational duration and spontaneous preterm birth”New England Journal of Medicine.06 September 2017.
Reproduction
Hellwege JN, Jeff JM, Wise LA et al.Show more authors. Hellwege JN, Jeff JM, Wise LA, Gallagher CS, Wellons M, Hartmann KE, Jones SF, Torstenson ES, Dickinson S, Ruiz-Narváez EA, Rohland N, Allen A, Reich D, Tandon A, Pasaniuc B, Mancuso N, Im HK, Hinds DA, Palmer JR, Rosenberg L, Denny JC, Roden DM, Stewart EA, Morton CC, Kenny EE, Edwards TL, Velez Edwards DR. Show fewer authors.“A multi-stage genome-wide association study of uterine fibroids in African Americans”Human Genetics.23 August 2017.
Reproduction
Boutwell B, Hinds D, Agee M et al.Show more authors. Boutwell B, Hinds D, Agee M, Alipanahi B, Auton A, Bell RK, Bryc K, Elson SL, Fontanillas P, Furlotte NA, Hromatka BS, Huber KE, Kleinman A, Litterman NK, McIntyre M, Mountain JM, Northerover CAM, Sathiraspongsasuti JF, Sazonova OV, Shelton JF. Shringarpure S, Tian C, Tung JY, Vacic V, Wilson CH, Tielbeek J, Ong KK, Day FR, Perry JRB. Show fewer authors.“Replication and characterization of CADM2 and MSRA genes on human behavior.”Heliyon.26 July 2017.
Behavior
Tsoi LC, Stuart PE, Tian C et al.Show more authors. Tsoi LC, Stuart PE, Tian C, Gudjonsson JE, Das S, Zawistowski M, Ellinghaus E, Barker JN, Chandran V, Dand N, Duffin KC, Enerbäck C, Esko T, Franke A, Gladman DD, Hoffmann P, Kingo K, Kõks S, Krueger GG, Lim HW, Metspalu A, Mrowietz U, Mucha S, Rahman P, Reis A, Tejasvi T, Trembath R, Voorhees JJ, Weidinger S, Weichenthal M, Wen X, Eriksson N, Kang HM, Hinds DA, Nair RP, Abecasis GR, Elder JT. Show fewer authors.“Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants.”Nature Communications.24 May 2017.
Dermatology
Immunity
Sapkota Y, Steinthorsdottir V, Morris AP et al.Show more authors. Sapkota Y, Steinthorsdottir V, Morris AP, Fassbender A, Rahmioglu N, De Vivo I, Buring JE, Zhang F, Edwards TL, Jones S, O D, Peterse D, Rexrode KM, Ridker PM, Schork AJ, MacGregor S, Martin NG, Becker CM, Adachi S, Yoshihara K, Enomoto T, Takahashi A, Kamatani Y, Matsuda K, Kubo M, Thorleifsson G, Geirsson RT, Thorsteinsdottir U, Wallace LM, iPSYCH-SSI-Broad Group, Yang J, Velez Edwards DR, Nyegaard M, Low S, Zondervan KT, Missmer SA, D'Hooghe T, Montgomery GW, Chasman I, Stefansson K, Tung JY, Nyholt DR. Show fewer authors.“Meta-analysis of 208,000 individuals identifies 18 risk loci for endometriosis and highlights key genes involved in hormone metabolism.”Nature Communications.24 May 2017.
Reproduction
Day FR, Thompson DJ, Helgason H et al.Show more authors. Day FR, Thompson DJ, Helgason H, Chasman DI, Finucane H, Sulem P, Ruth KS, Whalen S, Sarkar AK, Albrecht E, Altmaier E, Amini M, Barbieri CM, Boutin T, Campbell A, Demerath E, Giri A, He C, Hottenga JJ, Karlsson R, Kolcic I, Loh P, Lunetta KL, Mangino M, Marco B, McMahon G, Medland SE, Nolte IM, Noordam R, Nutile T, Paternoster L, Perjakova N, Porcu E, Rose LM, Schraut KE, Segre AV, Smith AV, Stolk L, Teumer A, Andrulis IL, Bandinelli S, Beckmann MW, Benitez J, Bergmann S, Bochud M, Boerwinkle E, Bojesen SE, Bolla MK, Brand JS, Brauch H, Brenner H, Broer L, Bruning T, Buring JE, Campbell H, Catamo E, Chanock S, Chenevix-Trench G, Corre T, Couch FJ, Cousminer DL, Cox A, Crisponi L, Czene K, Smith GD, de Geus EJCN, de Mutsert R, De Vivo I, Dennis J, Devilee P, dos-Santos-Silva I, Dunning AM, Eriksson JG, Fasching PA, Fernández-Rhodes L, Ferrucci L, Flesch-Janys D, Franke L, Gabrielson M, Gandin I, Giles GG, Grallert H, Gudbjartsson DF, Guenel P, Hall P, Hallberg E, Hamann U, Harris TB, Hartman CA, Heiss G, Hooning MJ, Hopper JL, Hu F, Hunter DJ, Ikram MA, Im HK, Jarvelin M , Joshi PK, Karasik D, Kellis M, Kutalik Z, LaChance G, Lambrechts D, Langenberg C, Launer LJ, Laven JSE, Lenarduzzi S, Li J, Lind PA, Lindstrom S, Liu Y, Luan J, Magi R, Mannermaa A, Mbarek H, McCarthy MI, Meisinger C, Meitinger T, Menni C, Metspalu A, Michailidou K, Milani L, Milne RL, Montgomery GW, Mulligan AM, Nalls MA, Navarro P, Nevanlinna H, Nyholt DR, Oldehinkel AJ, O'Mara TA, Padmanabhan S, Palotie A, Pedersen N, Peters A, Peto J, Pharoah PDP, Pouta A, Radice P, Rahman I, Ring SM, Robino A, Rosendaal FR, Rudan I, Rueedi R, Ruggiero D, Sala CF, Schmidt MK , Scott RA, Shah M, Sorice R, Southey MC, Sovio U, Stampfer M, Steri M, Strauch K, Tanaka T, Tikkanen E, Timpson NJ, Traglia M, Truong T, Tyrer JP, Uitterlinden AG, Edwards DRV, Vitart V, Volker U, Vollenweider P, Wang Q, Widen E, van Dijk KW, Willemsen G, Winqvist R, Wolffenbuttel BHR, Zhao JH, Zoledziewska M, Zygmunt M, Alizadeh BZ, Boomsma DI, Ciullo M, Cucca F, Esko T, Franceschini N, Gieger C, Gudnason V, Hayward C, Kraft P, Lawlor DA, Magnusson PKE, Martin NG, Mook-Kanamori DO, Nohr EA, Polasek O, Porteous D, Price AL, Ridker PM, Snieder H, Spector TD, Stockl D, Toniolo D, Ulivi S, Visser JA, Volzke H, Wareham NJ, Wilson JF, The LifeLines Cohort Study, The InterAct Consortium, kConFab/AOCS Investigators, Endometrial Cancer Association Consortium, Ovarian Cancer Association Consortium, PRACTICAL consortium, Spurdle AB, Thorsteindottir U, Pollard KS, Easton DF, Tung JY, Chang-Claude J, Hinds D, Murray A, Murabito JM, Stefansson K, Ong KK, Perry JRB. Show fewer authors.“Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility.”Nature Genetics.24 April 2017.
Cancer
Reproduction
Heilmann-Heimbach S, Herold C, Hochfeld LM et al.Show more authors. Heilmann-Heimbach S, Herold C, Hochfeld LM, Hillmer AM, Nyholt DR, Hecker J, Javed A, Chew EGY, Pechlivanis S, Drichel D, Heng XT, Rosario RCH, Fier HL, Paus R, Rueedi R, Galesloot TE, Moebus S, Anhalt T, Prabhakar S, Li R, Kanoni S, Papanikolaou G, Kutalik Z, Deloukas P, Philpott MP, Waeber G, Spector TD, Vollenweider P, Kiemeney LALM, Dedoussis G, Richards JB, Nothnagel M, Martin NG, Becker T, Hinds DA, Nöthen MM. Show fewer authors.“Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness.”Nature Communications.08 March 2017.
Dermatology
Traits
Kreiner E, Waage J, Standl M et al.Show more authors. Kreiner E, Waage J, Standl M, Brix S, Pers TH, Couto Alves A, Warrington NM, Tiesler CM, Fuertes E, Franke L, Hirschhorn JN, James A, Simpson A, Tung JY, Koppelman GH, Postma DS, Pennell CE, Jarvelin MR, Custovic A, Timpson N, Ferreira MA, Strachan DP, Henderson J, Hinds D, Bisgaard H, Bonnelykke K. Show fewer authors.“Shared genetic variants suggest common pathways in allergy and autoimmune diseases.”Journal of Allergy and Clinical Immunology.07 February 2017.
Immunity
Trampush JW, Yang ML, Yu J et al.Show more authors. Trampush JW, Yang ML, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Raikkonen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Roussos P, Giakoumaki S, Burdick KE, Payton A, Ollier W, Horan M, Chiba-Falek O, Attix DK, Need AC, Cirulli ET, Voineskos AN, Stefanis NC, Avramopoulos D, Hatzimanolis A, Arking DE, Smyrnis N, Bilder RM, Freimer NA, Cannon TD, London E, Poldrack RA, Sabb FW, Congdon E, Conley ED, Scult MA, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri AR, Weinberger DR, Pendleton N, Bitsios P, Rujescu D, Lahti J, Le Hellard S, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Malhotra AK, Lencz T. Show fewer authors.“GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium.”Molecular Psychiatry.17 January 2017.
Behavior
Robinson MR, Kleinman A, Graff M et al.Show more authors. Robinson MR, Kleinman A, Graff M, Vinkhuyzen AAE, Couper D, Miller MB, Peyrot WJ, Abdellaoui A, Zietsch BP, Nolte IM, Vliet-Ostaptchouk JV, Snieder H, The LifeLines Cohort Study, Genetic Investigation of Anthropometric Traits (GIANT) consortium, Medland SE, Martin NG, Magnusson PKE, Iacono WG, McGue M, North KE, Yang J, Visscher PM. Show fewer authors.“Genetic evidence of assortative mating in humans.”Nature Human Behavior.09 January 2017.
Lo MT, Hinds DA, Tung JY et al.Show more authors. Lo MT, Hinds DA, Tung JY, Franz C, Fan CC, Wang Y, Smeland OB, Schork A, Holland D, Kauppi K, Sanyal N, Escott-Price V, Smith DJ, O'Donovan M, Stefansson H, Bjornsdottir G, Thorgeirsson TE, Stefansson K, McEvoy LK, Dale AM, Andreassen OA, Chen CH. Show fewer authors.“Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders.”Nature Genetics.05 December 2016.
Behavior
Psychiatry
Jones SE, Tyrrell J, Wood AR et al.Show more authors. Jones SE, Tyrrell J, Wood AR, Beaumont RN, Ruth KS, Tuke MA, Yaghootkar H, Hu Y, Teder-Laving M, Hayward C, Roenneberg T, Wilson JF, Del Greco F, Hicks AA, Shin C, Yun CH, Lee SK, Metspalu A, Byrne EM, Gehrman PR, Tiemeier H, Allebrandt KV, Freathy RM, Murray A, Hinds DA, Frayling TM, Weedon MN. Show fewer authors.“Genome-wide association analyses in 128,266 individuals identifies new morningness and sleep duration loci.”PLoS Genetics.05 August 2016.
Behavior
Rietveld CA, Turley P, Chen GB et al.Show more authors. Rietveld CA, Turley P, Chen GB, Emilsson V, Meddens SF, Oskarsson S, Pickrell JK, Thom K, Timshel P, de Vlaming R, Abdellaoui A, Ahluwalia TS, Bacelis J, Baumbach C, Bjornsdottir G, Brandsma JH, Pina Concas M, Derringer J, Furlotte NA, Galesloot TE, Girotto G, Gupta R, Hall LM, Harris SE, Hofer E, Horikoshi M, Huffman JE, Kaasik K, Kalafati IP, Karlsson R, Kong A, Lahti J, van der Lee SJ, deLeeuw C, Lind PA, Lindgren KO, Liu T, Mangino M, Marten J, Mihailov E, Miller MB, van der Most PJ, Oldmeadow C, Payton A, Pervjakova N, Peyrot WJ, Qian Y, Raitakari O, Rueedi R, Salvi E, Schmidt B, Schraut KE, Shi J, Smith AV, Poot RA, St Pourcain B, Teumer A, Thorleifsson G, Verweij N, Vuckovic D, Wellmann J, Westra HJ, Yang J, Zhao W, Zhu Z, Alizadeh BZ, Amin N, Bakshi A, Baumeister SE, Biino G, Bonnelykke K, Boyle PA, Campbell H, Cappuccio FP, Davies G, De Neve JE, Deloukas P, Demuth I, Ding J, Eibich P, Eisele L, Eklund N, Evans DM, Faul JD, Feitosa MF, Forstner AJ, Gandin I, Gunnarsson B, Halldorsson BV, Harris TB, Heath AC, Hocking LJ, Holliday EG, Homuth G, Horan MA, Hottenga JJ, de Jager PL, Joshi PK, Jugessur A, Kaakinen MA, Kahonen M, Kanoni S, Keltigangas-Jarvinen L, Kiemeney LA, Kolcic I, Koskinen S, Kraja AT, Kroh M, Kutalik Z, Latvala A, Launer LJ, Lebreton MP, Levinson DF, Lichtenstein P, Lichtner P, Liewald DC; LifeLines Cohort Study, Loukola A, Madden PA, Magi R, Maki-Opas T, Marioni RE, Marques-Vidal P, Meddens GA, McMahon G, Meisinger C, Meitinger T, Milaneschi Y, Milani L, Montgomery GW, Myhre R, Nelson CP, Nyholt DR, Ollier WE, Palotie A, Paternoster L, Pedersen NL, Petrovic KE, Porteous DJ, Raikkonen K, Ring SM, Robino A, Rostapshova O, Rudan I, Rustichini A, Salomaa V, Sanders AR, Sarin AP, Schmidt H, Scott RJ, Smith BH, Smith JA, Staessen JA, Steinhagen-Thiessen E, Strauch K, Terracciano A, Tobin MD, Ulivi S, Vaccargiu S, Quaye L, van Rooij FJ, Venturini C, Vinkhuyzen AA, Volker U, Volzke H, Vonk JM, Vozzi D, Waage J, Ware EB, Willemsen G, Attia JR, Bennett DA, Berger K, Bertram L, Bisgaard H, Boomsma DI, Borecki IB, Bultmann U, Chabris CF, Cucca F, Cusi D, Deary IJ, Dedoussis GV, van Duijn CM, Eriksson JG, Franke B, Franke L, Gasparini P, Gejman PV, Gieger C, Grabe HJ, Gratten J, Groenen PJ, Gudnason V, van der Harst P, Hayward C, Hinds DA, Hoffmann W, Hypponen E, Iacono WG, Jacobsson B, Jarvelin MR, Jockel KH, Kaprio J, Kardia SL, Lehtimaki T, Lehrer SF, Magnusson PK, Martin NG, McGue M, Metspalu A, Pendleton N, Penninx BW, Perola M, Pirastu N, Pirastu M, Polasek O, Posthuma D, Power C, Province MA, Samani NJ, Schlessinger D, Schmidt R, Sorensen TI, Spector TD, Stefansson K, Thorsteinsdottir U, Thurik AR, Timpson NJ, Tiemeier H, Tung JY, Uitterlinden AG, Vitart V, Vollenweider P, Weir DR, Wilson JF, Wright AF, Conley DC, Krueger RF, Davey Smith G, Hofman A, Laibson DI, Medland SE, Meyer MN, Yang J, Johannesson M, Visscher PM, Esko T, Koellinger PD, Cesarini D, Benjamin DJ. Show fewer authors.“Genome-wide association study identifies 74 loci associated with educational attainment.”Nature.11 May 2016.
Behavior
Okbay A, Beauchamp JP, Fontana MA et al.Show more authors. Okbay A, Beauchamp JP, Fontana MA, Lee JJ, Pers TH, Fontana MA, Meddens SF, Linner RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, Buchwald J, Cavadino A, Frazier-Wood AC, Furlotte NA, Garfield V, Geisel MH, Gonzalez JR, Haitjema S, Karlsson R, van der Laan SW, Ladwig KH, Lahti J, van der Lee SJ, Lind PA, Liu T, Matteson L, Mihailov E, Miller MB, Minica CC, Nolte IM, Mook-Kanamori D, van der Most PJ, Oldmeadow C, Qian Y, Raitakari O, Rawal R, Realo A, Rueedi R, Schmidt B, Smith AV, Stergiakouli E, Tanaka T, Taylor K, Wedenoja J, Wellmann J, Westra HJ, Willems SM, Zhao W; LifeLines Cohort Study, Amin N, Bakshi A, Boyle PA, Cherney S, Cox SR, Davies G, Davis OS, Ding J, Direk N, Eibich P, Emeny RT, Fatemifar G, Faul JD, Ferrucci L, Forstner A, Gieger C, Gupta R, Harris TB, Harris JM, Holliday EG, Hottenga JJ, De Jager PL, Kaakinen MA, Kajantie E, Karhunen V, Kolcic I, Kumari M, Launer LJ, Franke L, Li-Gao R, Koini M, Loukola A, Marques-Vidal P, Montgomery GW, Mosing MA, Paternoster L, Pattie A, Petrovic KE, Pulkki-Raback L, Quaye L, Raikkonen K, Rudan I, Scott RJ, Smith JA, Sutin AR, Trzaskowski M, Vinkhuyzen AE, Yu L, Zabaneh D, Attia JR, Bennett DA, Berger K, Bertram L, Boomsma DI, Snieder H, Chang SC, Cucca F, Deary IJ, van Duijn CM, Eriksson JG, Bultmann U, de Geus EJ, Groenen PJ, Gudnason V, Hansen T, Hartman CA, Haworth CM, Hayward C, Heath AC, Hinds DA, Hypponen E, Iacono WG, Jarvelin MR, Jockel KH, Kaprio J, Kardia SL, Keltikangas-Jarvinen L, Kraft P, Kubzansky LD, Lehtimaki T, Magnusson PK, Martin NG, McGue M, Metspalu A, Mills M, de Mutsert R, Oldehinkel AJ, Pasterkamp G, Pedersen NL, Plomin R, Polasek O, Power C, Rich SS, Rosendaal FR, den Ruijter HM, Schlessinger D, Schmidt H, Svento R, Schmidt R, Alizadeh BZ, Sorensen TI, Spector TD, Steptoe A, Terracciano A, Thurik AR, Timpson NJ, Tiemeier H, Uitterlinden AG, Vollenweider P, Wagner GG, Weir DR, Yang J, Conley DC, Smith GD, Hofman A, Johannesson M, Laibson DI, Medland SE, Meyer MN, Pickrell JK, Esko T, Krueger RF, Beauchamp JP, Koellinger PD, Benjamin DJ, Bartels M, Cesarini D. Show fewer authors.“Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.”Nature Genetics.18 April 2016.
Behavior
Psychiatry
Chen R, Shi L, Hakenberg J et al.Show more authors. Chen R, Shi L, Hakenberg J, Naughton B, Sklar P, Zhang J, Zhou H, Tian L, Prakash O, Lemire M, Sleiman P, Cheng WY, Chen W, Shah H, Shen Y, Fromer M, Omberg L, Deardorff MA, Zackai E, Bobe JR, Levin E, Hudson TJ, Groop L, Wang J, Hakonarson H, Wojcicki A, Diaz G, Edelmann L, Schadt EE, Friend SH. Show fewer authors.“Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases.”Nature Biotechnology.11 April 2016.
Rare Diseases
Hinds DA, Buil A, Ziemek D et al.Show more authors. Hinds DA, Buil A, Ziemek D, Martinez-Perez A, Malik R, Folkersen L, Germain M, Malarstig A, Brown A, Soria JM, Dichgans M, Bing N, Franco-Cereceda A, Souto JC, Dermitzakis ED, Hamsten A, Worrall BB, Tung JY, METASTROKE Consortium, INVENT Consortium, Sabater-Lleal M. Show fewer authors.“Genome-wide association analysis in 6,135 individuals and 252,827 controls identifies 8 loci associated with thrombosis.”Human Molecular Genetics.09 February 2016.
Hematology
Minikel EV, Vallabh SM, Lek M et al.Show more authors. Minikel EV, Vallabh SM, Lek M, Estrada K, Samocha KE, Sathirapongsasuti JF, McLean CY, Tung JY, Yu LP, Gambetti P, Blevins J, Zhang S, Cohen Y, Chen W, Yamada M, Hamaguchi T, Sanjo N, Mizusawa H, Nakamura Y, Kitamoto T, Collins SJ, Boyd A, Will RG, Knight R, Ponto C, Zerr I, Kraus TF, Eigenbrod S, Giese A, Calero M, de Pedro-Cuesta J, Haik S, Laplanche JL, Bouaziz-Amar E, Brandel JP, Capellari S, Parchi P, Poleggi A, Ladogana A, O'Donnell-Luria AH, Karczewski KJ, Marshall JL, Boehnke M, Laakso M, Mohlke KL, Kahler A, Chambert K, McCarroll S, Sullivan PF, Hultman CM, Purcell SM, Sklar P, van der Lee SJ, Rozemuller A, Jansen C, Hofman A, Kraaij R, van Rooij JG, Ikram MA, Uitterlinden AG, van Duijn CM; Exome Aggregation Consortium (ExAC), Daly MJ, MacArthur DG. Show fewer authors.“Quantifying prion disease penetrance using large population control cohorts.”Science Translational Medicine.20 January 2016.
Neurology
Rare Diseases
Paternoster L, Standl M, Waage J et al.Show more authors. Paternoster L, Standl M, Waage J, Baurecht H, Hotze M, Strachan DP, Curtin JA, Bonnelykke K, Tian C, Takahashi A, Esparza-Gordillo J, Alves AC, Thyssen JP, den Dekker HT, Ferreira MA, Altmaier E, Sleiman PMA, Xiao FL, Gonzalez JR, Marenholz I, Kalb B, Pino-Yanes M, Xu CJ, Carstensen L, Groen-Blokhuis MM, Venturini C, Pennell CE, Barton SJ, Levin AM, Curjuric I, Bustamante M, Kreiner-Moller E, Lockett GA, Bacelis J, Bunyavanich S, Myers RA, Matanovic A, Kumar A, Tung JY, Hirota T, Kubo M, McArdle WL, Henderson AJ, Kemp JP, Zheng J, Smith GD, Ruschendorf F, Bauerfeind A, Lee-Kirsch MA, Arnold A, Homuth G, Schmidt CO, Mangold E, Cichon S, Keil T, Rodriguez E, Peters A, Franke A, Lieb W, Novak N, Folster-Holst R, Horikoshi M, Pekkanen J, Sebert S, Husemoen LL, Grarup N, de Jongste JC, Rivadeneira F, Hofman A, Jaddoe VWV, Pasmans SGMA, Elbert NJ, Uitterlinden AG, Marks GB, Thompson PJ, Matheson MC, Robertson CF, Australian Asthma Genetics Consortium (AAGC), Ried JS, Li J, Zuo XB, Zheng XD, Yin XY, Sun LD, McAleer MA, O'Regan GM, Fahy CMR, Campbell LE, Macek M, Kurek M, Hu D, Eng C, Postma D, Feenstra B, Geller F, Hottenga JJ, Middeldorp CM, Hysi P, Bataille V, Spector T, Tiesler CMT, Thiering E, Pahukasahasram B, Yang JJ, Imboden M, Huntsman S, Vilor-Tejedor N, Relton CL, Myhre R, Nystad W, Custovic A, Weiss ST, Meyers DA, Soderhall C, Melen E, Ober C, Raby BA, Simpson A, Jacobsson B, Holloway JW, Bisgaard H, Sunyer J, Probst-Hensch NM, Williams LK, Godfrey KM, Wang CA, Boomsma DI, Melbye M, Koppelman GH, Jarvis D, McLean WHI, Irvine AD, Zhang XJ, Hakonarson H, Gieger C, Burchard EG, Martin NG, Duijts L, Linneberg A, Jarvelin MR, Nothen MM, Lau S, Hubner N, Lee YA, Tamari M, Hinds DA, Glass D, Brown SJ, Heinrich J, Evans DM, and Stephan Weidinger for the EArly Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium. Show fewer authors.“Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.”Nature Genetics.19 October 2015.
Dermatology
Immunity
Day FR, Hinds DA, Tung JY et al.Show more authors. Day FR, Hinds DA, Tung JY, Stolk L, Styrkarsdottir U, Saxena R, Bjonnes A, Broer L, Dunger DB, Halldorsson BV, Lawlor DA, Laval G, Mathieson I, McCardle WL, Louwers Y, Meun C, Ring S, Scott RA, Sulem P, Uitterlinden AG, Wareham NJ, Thorsteinsdottir U, Welt C, Stefansson K, Laven JSE, Ong KK, Perry JRB. Show fewer authors.“Causal mechanisms and balancing selection inferred from genetic associations with the Polycystic Ovary Syndrome.”Nature Communications.25 September 2015.
Reproduction
Zheng HF, Forgetta V, Hsu YH et al.Show more authors. Zheng HF, Forgetta V, Hsu YH, Estrada K, Rosello-Diez A, Leo PJ, Dahia CL, Park-Min KH, Tobias JH, Kooperberg C, Kleinman A, Styrkarsdottir U, Liu CT, Uggla C, Evan DS, Nielson CM, Walter K, Pettersson-Kymmer U, McCarthy S, Eriksson J, Kwan T, Jhamai M, Trajanoska K, Memari Y, Min J, Huang J, Danecek P, Wilmot B, Li R, Chou WC, Mokry LE, Moayyeri A, Claussnitzer M, Cheng CH, Cheung W, Medina-Gomez C, Ge B, Chen SH, Choi K, Oei L, Fraser J, Kraaij R, Hibbs MA, Gregson CL, Paquette D, Hofman A, Wibom C, Tranah GJ, Marshall M, Gardiner BB, Cremin K, Auer P, Hsu L, Ring S, Tung JY, Thorleifsson G, Enneman AW, van Schoor NM, de Groot LCPGM, van der Velde N, Melin B, Kemp JP, Christiansen C, Sayers A, Zhou Y, Calderari S, van Rooij J, Carlson C, Peters U, Berlivet S, Dostie J, Uitterlinden AG, Williams SR, Farber C, Grinberg D, LaCroix AZ, Haessler J, Chasman DI, Giulianini F, Rose LM, Ridker PM, Eisman JA, Nguyen TV, Center JR, Nogues X, Garcia-Giralt N, Launer LL, Gudnason V, Mellstrom D, Vandenput L, Amin N, van Duijn CM, Karlsson MK, Ljunggren O, Svensson O, Hallmans G, Rousseau F, Giroux S, Bussiere J, Arp PP, Koromani F, Prince RL, Lewis JR, Langdahl BL, Hermann AP, Jensen JEB, Kaptoge S, Khaw KT, Reeve J, Formosa MM, Xuereb-Anastasi A, Akesson K, McGuigan FE, Garg G, Olmos JM, Zarrabeitia MT, Riancho JA, Ralston SH, Alonso N, Jiang X, Goltzman D, Pastinen T, Grundberg E, Gauguier D, Orwoll ES, Karasik D, Davey-Smith G, AOGC Consortium, Smith AV, Siggeirsdottir K, Harris TB, Zillikens MC, van Meurs JBJ, Thorsteinsdottir U, Maurano MT, Timpson NJ, Soranzo N, Durbin R, Wilson SG, Ntzani EE, Brown MA, Stefansson Kari, Hinds DA, Spector T, Cupples LA, Ohlsson C, Greenwood CMT, UK10K Consortium, Jackson RD, Rowe DW, Loomis CA, Evans DM, Ackert-Bicknell CL, Joyner AL, Duncan EL, Kiel DP, Rivadeneira F, Richards JB. Show fewer authors.“Whole-genome sequencing and deep imputation identifies non-coding variants near Engrailed-1 with large effects on bone mineral density and fracture.”Nature.14 September 2015.
Musculoskeletal
Nalls MA, McLean CY, Rick J et al.Show more authors.Nalls MA, McLean CY, Rick J, Eberly S, Hutten SJ, Gwinn K, Sutherland M, Martinez M, Heutink P, Williams NM, Hardy J, Gasser T, Brice A, Price TR, Nicolas A, Keller MF, Molony C, Gibbs JR, Chen-Plotkin A, Suh E, Letson C, Fiandaca MS, Mapstone M, Federoff HJ, Noyce AJ, Morris H, Van Deerlin VM, Weintraub D, Zabetian C, Hernandez DG, Lesage S, Mullins M, Conley ED, Northover CAM, Frasier M, Marek K, Day-Williams AG, Stone DJ, Ioannidis JPA, Singleton AB, for the Parkinson's Disease Biomarkers Program and Parkinson's Progression Marker Initiative investigators. Show fewer authors.“Diagnosis of Parkinson’s disease on the basis of clinical and genetic classification: a population-based modelling study.”Lancet Neuro.10 August 2015.
Neurology
Lunetta KL, Day FR, Sulem P et al.Show more authors. Lunetta KL, Day FR, Sulem P, Ruth KS, Tung JY, Hinds DA, Esko T, Elks CE, Altmaier E, He C, Huffman JE, Mihailov E, Porcu E, Robino A, Rose LM, Schick UM, Stolk L, Teumer A, Thompson DJ, Traglia M, Wang CA, Yerges-Armstrong LM, Antoniou AC, Barbieri C, Coviello AD, Cucca F, Demerath EW, Dunning AM, Gandin I, Grove ML, Gudbjartsson DF, Hocking LJ, Hofman A, Huang J, Jackson RD, Karasik D, Kriebel J, Lange EM, Lange LA, Langenberg C, Li X, Luan J, Magi R, Morrison AC, Padmanabhan S, Pirie A, Polasek O, Porteous D, Reiner AP, Rivadeneira F, Rudan I, Sala CF, Schlessinger D, Scott RA, Stockl D, Visser JA, Volker U, Vozzi D, Wilson JG, Zygmunt M, EPIC-InterAct Consortium, Generation Scotland, Boerwinkle E, Buring JE, Crisponi L, Easton DF, Hayward C, Hu FB, Liu S, Metspalu A, Pennell CE, Ridker PM, Strauch K, Streeten EA, Toniolo D, Uitterlinden AG, Ulivi S, Volzke H, Wareham NJ, Wellons M, Franceschini N, Chasman DI, Thorsteinsdottir U, Murray A, Stefansson K, Murabito JM, Ong KK, Perry JRB. Show fewer authors.“Rare coding variants and X-linked loci associated with age at menarche.”Nature Communications.04 August 2015.
Reproduction
Meisel SF, Carere DA, Wardle J et al.Show more authors. Meisel SF, Carere DA, Wardle J, Kalia SS, Moreno TA, Mountain JL, Roberts JS, Green RC; PGen Study Group. Show fewer authors.“Explaining, not just predicting, drives interest in personal genomics.”Genome Medicine.01 August 2015.
ELSI
Arloth J, Bogdan R, Weber P et al.Show more authors. Arloth J, Bogdan R, Weber P, Frishman G, Menke A, Wagner KV, Balsevich G, Schmidt MV, Karbalai N, Czamara D, Altmann A, Trumbach D, Wurst W, Mehta D, Uhr M, Klengel T, Erhardt A, Carey CE, Conley ED, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (PGC), Ruepp A, Muller-Myhsok B, Hariri AR, Binder EB. Show fewer authors.“Genetic differences in the immediate transcriptome response to stress predict risk-related brain function and psychiatric disorders.”Neuron.03 June 2015.
Neurology
Psychiatry
Chang AL, Raber I, Xu J et al.Show more authors. Chang AL, Raber I, Xu J, Li R, Spitale R, Chen J, Kiefer AK, Tian C, Eriksson NK, Hinds DA, Tung JY. Show fewer authors.“Assessment of the genetic basis of rosacea by genome-wide association study.”Journal of Investigative Dermatology.12 March 2015.
Dermatology
Immunity
Rietveld CA, Conley D, Eriksson N et al.Show more authors. Rietveld CA, Conley D, Eriksson N, Esko T, Medland SE, Vinkhuyzen AA, Yang J, Boardman JD, Chabris CF, Dawes CT, Domingue BW, Hinds DA, Johannesson M, Kiefer AK, Laibson D, Magnusson PK, MMountain JL, Oskarsson S, Rostapshova O, Teumer A, Tung JY, Visscher PM, Benjamin DJ, Cesarini D, Koellinger PD; the Social Science Genetics Association Consortium; the Social Science Genetics Association Consortium. Show fewer authors.“Replicability and robustness of genome-wide-association studies for behavioral traits.”Psychological Science.06 October 2014.
Behavior
Nalls MA, Bras J, Hernandez DG et al.Show more authors. Nalls MA, Bras J, Hernandez DG, Keller MF, Majounie E, Renton AE, Saad M, Jansen I, Guerreiro R, Lubbe S, Plagnol V, Gibbs JR, Schulte C, Pankratz N, Sutherland M, Bertram L, Lill CM, DeStefano AL, Faroud T, Eriksson N, Tung JY, Edsall C, Nichols N, Brooks J, Arepalli S, Pliner H, Letson C, Heutink P, Martinez M, Gasser T, Traynor BJ, Wood N, Hardy J, Singleton AB; the International Parkinson's Disease Genomics Consortium (IPDGC) and the Parkinson's Disease meta-analysis consortium. Show fewer authors.
NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseases.
Neurobiology of Aging.04 August 2014.
Neurology
Nalls MA, Pankratz N, Lill CM et al.Show more authors. Nalls MA, Pankratz N, Lill CM, Do CB, Hernandez DG, Saad M, DeStefano AL, Kara E, Bras J, Sharma M, Schulte C, Keller MF, Arepalli S, Letson C, Edsall C, Stefansson H, Liu X, Pliner H, Lee JH, Cheng R; International Parkinson's Disease Genomics Consortium (IPDGC); Parkinson's Study Group (PSG) Parkinson's Research: The Organized GENetics Initiative (PROGENI); 23andMe; GenePD; NeuroGenetics Research Consortium (NGRC); Hussman Institute of Human Genomics (HIHG); The Ashkenazi Jewish Dataset Investigator; Cohorts for Health and Aging Research in Genetic Epidemiology (CHARGE); North American Brain Expression Consortium (NABEC); United Kingdom Brain Expression Consortium (UKBEC); Greek Parkinson's Disease Consortium; Alzheimer Genetic Analysis Group, Ikram MA, Ioannidis JP, Hadjigeorgiou GM, Bis JC, Martinez M, Perlmutter JS, Goate A, Marder K, Fiske B, Sutherland M, Xiromerisiou G, Myers RH, Clark LN, Stefansson K, Hardy JA, Heutink P, Chen H, Wood NW, Houlden H, Payami H, Brice A, Scott WK, Gasser T, Bertram L, Eriksson N, Foroud T, Singleton AB. Show fewer authors.“Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson’s disease.”Nature Genetics.27 July 2014.
Neurology
Ferreira MA, Matheson MC, Tang CS et al.Show more authors. Ferreira MA, Matheson MC, Tang CS, Granell R, Ang W, Hui J, Kiefer AK, Duffy DL, Baltic S, Danoy P, Bui M, Price L, Sly PD, Eriksson N, Madden PA, Abramson MJ, Holt PG, Heath AC, Hunter M, Musk B, Robertson CF, Le Souef P, Montgomery GW, Henderson AJ, Tung JY, Dharmage SC, Brown MA, James A, Thompson PJ, Pennell C, Martin NG, Evans DM, Hinds D, Hopper JL, the Australian Asthma Genetics Consortium Collaborators. Show fewer authors.“Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.”Journal of Allergy and Clinical Immunology.31 December 2013.
Immunity
Revez JA, Bain L, Chapman B et al.Show more authors. Revez JA, Bain L, Chapman B, Powell JE, Jansen R, Duffy DL, Tung JY, AAGC Collaborators, Penninx BW, Visscher PM, De Geus EJC, Boomsma DI, Hinds DA, Martin NG, Montgomery GW, Ferreira MAR. Show fewer authors.
A new regulatory variant in the interleukin-6 receptor gene associates with asthma risk.
Genes and Immunity.15 August 2013.
Immunity
Pichler I, Del Greco FM, Gogele M et al.Show more authors.Pichler I, Del Greco FM, Gogele M, Lill CM, Bertram L, Do CB, Eriksson N, Foroud T, Myers RH, PD GWAS Consortium, Nalls M, Keller MF, International Parkinson's Disease Genomics Consortium, Wellcome Trust Case Control Consortium 2, Benyamin B, Whitfield JB, Genetics of Iron Status Consortium, Pramstaller PP, Hicks AA, Thompson JR, Minelli C. Show fewer authors.“Serum iron levels and the risk of Parkinson’s disease: a Mendelian randomization study.”PLOS Medicine.04 June 2013.
Neurology
Heilmann S, Kiefer AK, Fricker N et al.Show more authors. Heilmann S, Kiefer AK, Fricker N, Drichel D, Hillmer AM, Herold C, Tung JY, Eriksson N, Redler S, Betz RC, Li R, Karason A, Nyholt DR, Song K, Vermeulen SH, Kanoni S, Dedoussis G, Martin NG, Kiemeny LA, Mooser V, Stefansson K, Richards JB, Becker T, Brockschmidt FF, Hinds DA, Nothen MM. Show fewer authors.“Androgenetic alopecia: identification of four new genetic risk loci and evidence for the contribution of WNT-signaling to its etiology.”Journal of Investigative Dermatology.28 January 2013.
Dermatology
Li R, Brockschmidt FF, Kiefer AK et al.Show more authors. Li R, Brockschmidt FF, Kiefer AK, Stefansson H, Nyholt DR, Song K, Vermeulen SH, Kanoni S, Glass D, Medland SE, Dimitriou M, Waterworth D, Tung JY, Geller F, Heilmann S, Hillmer AM, Bataille V, Eigelshoven S, Hanneken S, Moebus S, Herold C, den Heijer M, Montgomery GW, Deloukas P, Eriksson N, Heath AC, Becker T, Sulem P, Mangino M, Vollenweider P, Spector TD, Dedoussis G, Martin NG, Kiemeney LA, Mooser V, Stefansson K, Hinds DA, Nothen MM, Richards JB. Show fewer authors.“Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases.”PLoS Genetics.31 May 2012.
Dermatology
Lill CM, Roehr JT, McQueen MB et al.Show more authors. Lill CM, Roehr JT, McQueen MB, Kavvoura FK, Bagade S, Schjeide BM, Schjeide LM, Meissner E, Zauft U, Allen NC, Liu T, Schilling M, Anderson KJ, Beecham G, Berg D, Biernacka JM, Brice A, DeStefano AL, Do CB, Eriksson N, Factor SA, Farrer MJ, Foroud T, Gasser T, Hamza T, Hardy JA, Heutink P, Hill-Burns EM, Klein C, Latourelle JC, Maraganore DM, Martin ER, Martinez M, Myers RH, Nalls MA, Pankratz N, Payami H, Satake W, Scott WK, Sharma M, Singleton AB, Stefansson K, Toda T, Tung JY, Vance J, Wood NW, Zabetian CP; 23andMe Genetic Epidemiology of Parkinson's Disease Consortium; International Parkinson's Disease Genomics Consortium; Parkinson's Disease GWAS Consortium; Wellcome Trust Case Control Consortium 2), Young P, Tanzi RE, Khoury MJ, Zipp F, Lehrach H, Ioannidis JP, Bertram L. Show fewer authors.“Comprehensive research synopsis and systematic meta-analyses in Parkinson’s Disease: The PDGene database.”PLoS Genetics.15 March 2012.
Neurology
Henn BM, Gignoux CR, Jobin M et al.Show more authors. Henn BM, Gignoux CR, Jobin M, Granka JM, Macpherson JM, Kidd JM, Rodriguez-Botigue L, Ramachandran S, Hon L, Brisbin A, Lin AA, Underhill PA, Comas D, Kidd KK, Norman PJ, Parham P, Bustamante CD, Mountain JL, Feldman MW. Show fewer authors.“Hunter-gatherer genomic diversity suggests a southern African origin for modern humans.”PNAS.01 March 2011.
Ancestry
