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Howard DM, Adams MJ, Clarke T, Hafferty JD, Gibson J. et al.Show more authors.Howard DM, Adams MJ, Clarke T, Hafferty JD, Gibson J, Shirali M, Coleman JRI, Hagenaars SP, Ward J, Wigmore EM, Alloza C, Shen X, Barbu MC, Xu EY, Whalley HC, Marioni RE, Porteous DJ, Davies G, Deary IJ, Hemani G, Berger K, Teismann H, Rawal R, Arolt V, Baune BT, Dannlowski U, Domschke K, Tian C, Hinds DA, 23andMe Research Team, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Trzaskowski M, Byren EM, Ripke S, Smith DJ, Sullivan PF, Wray NR, Breen G, Lewis CM, McIntosh AM. Show fewer authors.“Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.”
Nature Neuroscience. 4 February 2019.
Psychiatry
Jones SE, Lane JM, Wood AR, van Hees VT, Tyrrell J. et al.Show more authors.Jones SE, Lane JM, Wood AR, van Hees VT, Tyrrell J, Beaumont RN, Jeffries AR, Dashti HS, Hillsdon M, Ruth KS, Tuke MA, Yaghootkar H, Sharp SA, Jie Y, Thompson WD, Harrison JW, Dawes A, Byren EM, Tiemeier H, Allebrandt KV, Bowden J, Ray DW, Freathy RM, Murray A, Mazzotti DR, Gehrman PR, Lawlor DA, Frayling TM, Rutter MK, Hinds DA, Saxena R, Weedon, MN. Show fewer authors.“Genome-wide association analyses of chronotype in 697,828 individuals provides new insights into circadian rhythms in humans and links to disease.”
Nature Communications. 29 January 2019.
Neurology
Linnér RK, Biroli P, Kong E, Meddens SFW, Wedow R. et al.Show more authors.Linnér RK, Biroli P, Kong E, Meddens SFW, Wedow R, Fontana MA, Lebreton M, Abdellaoui A, Hammerschlag AR, Nivard MG, Okbay A, Rietveld CA, Timshel PN, Tino SP, Trzaskowski M, de Vlaming R, Zünd CL, Bao Y, Buzdugan L, Caplin AH, Chen C, Eibich P, Fontanillas P, Gonzalez JR, Joshi PK, Karhunen V, Kleinman A, Levin RZ, Lill CM, Meddens GA, Muntané G, Sanchez-Roige S, van Rooij FJ, Taskesen E, Wu Y, Zhang F, 23andMe Research Team, eQTLgen Consortium, International Cannabis Consortium, Psychiatric Genomics Consortium, Social Science Genetic Association Consortium, Auton A, Boardman JD, Clark DW, Conlin A, Dolan CC, Fischbacher U, Groenen PJF, Harris KM, Hasler G, Hofman A, Ikram M, Jain S, Karlsson R, Kessler R, Kooyman M, MacKillop J, Männikkö M, Morcillo-Suarez C, McQueen MB, Schmidt KM, Smart MC, Sutter M, Thurik AR, Uitterlinden AG, White J, de Wit H, Yang J, Bertram L, Boomsma D, Esko T, Fehr E, Hinds DA, Johannesson M, Kumari M, Laibson D, Magnusson PKE, Meyer MN, Navarro A, Palmer AA, Pers TH, Posthuma D, Schunk D, Stein MB, Svento R, Tiemeier H, Timmers PRHJ, Turley P, Ursano RJ, Wagner GG, Wilson JF, Gratten J, Lee JJ, Cesarini D, Benjamin DJ, Koellinger P, Beauchamp JP. Show fewer authors.“GWAS of risk tolerance and risky behaviors in over one million individuals identify hundreds of loci and reveal shared genetic influences.”
Nature Genetics. 14 January 2019.
Behavior
Liu M, Jiang Y, Wedow R, Li Y, Brazel DM. et al.Show more authors.Liu M, Jiang Y, Wedow R, Li Y, Brazel DM, Chen F, Datta G, Davila-Velderrain J, McGuire D, Tian C, Zhan X, 23andMe Research Team, HUNT All-In Psychiatry, Choquet H, Docherty AR, Faul JD, Foerster JR, Fristche LG, Gabrielsen ME, Gordon SD, Haessler J, Hottenga J, Huang H, Jang S, Jansen PR, Ling Y, Mägi R, Matoba N, McMahon G, Mulas A, Orrù V, Palviainen T, Pandit A, Reginsson GW, Skogholt AH, Smith JA, Taylor AE, Turman C, Willemsen G, Young H, Young KA, Zajac GJM, Zhao W, Zhou W, Bjornsdottir G, Boardman JD, Boehnke M, Boomsma DI, Chen C, Cucca F, Davies GE, Eaton CB, Ehringer MA, Esko T, Fiorillo E, Gillespie NA, Gudbjartsson DF, Haller T, Harris KM, Heath AC, Hewitt JK, Hickie IB, Hokanson JE, Hopfer CJ, Hunger DJ, Iacono WG, Johnson EO, Kamatani Y, Kardia SLR, Keller MC, Kellis M, Kooperberg C, Kraft P, Krauter KS, Laakso M, Lind PA, Luokola A, Lutz SM, Madden PAF, Martin NG, McGue M, McQueen MB, Medland SE, Metspalu A, Mohlke KL, Nielsen JB, Okada Y, Peters U, Polderman TJC, Posthuma D, Reiner AP, Rice JP, Rimm E, Rose RJ, Runarsdottir V, Stallings MC, Stančáková, Stegansson H, Thai KK, Tindle HA, Tyrfingsson T, Wall TL, Weir DR, Weisner C, Whitfield JB, Winsvold BS, Yin J, Zuccolo L, Bierut LJ, Hveem K, Lee JJ, Munafò, Sccone NL, Willer CJ, Corenlis MC, David SP, Hinds DA, Jorgenson E, Kaprio J, Stitzel JA, Stefansson K, Thorgeirsson TE, Abecasis G, Liu DJ, Vrieze S. Show fewer authors.“Association studies of up to 1.2 million individuals yield new insights in the genetic etiology of tobacco and alcohol use.”
Nature Genetics. 14 January 2019.
Behavior
Day F, Karaderi T, Jones MR, Meun C, He C. et al.Show more authors.Day F, Karaderi T, Jones MR, Meun C, He C, Drong A, Kraft P, Lin N, Huang H, Broer L, Magi R, Saxena R, Laisk T, Urbanek M, Hayes MG, Thorleitfsson G, Fernandez-Tajes J, Mahajan A, Mullin BH, Stuckey MGA, Spector TD, Wilson SG, Goodarzi MO, Davis L, Obermayer-Pietsch B, Uitterlinden AG, Anttila V, Neale BM, Jarvelin M, Fauser B, Kowalska I, Visser JA, Andersen M, Ong K, Stener-Victorin E, Ehrmann D, Legro RS, Salumets A, McCarthy MI, Morin-Papunen L, Thorsteinsdottir U, Stegansson K, the 23andMe Research Team, Styrkarsdottir U, Perry JRB, Dunaif A, Laven K, Franks S, Lindgren CM, Welt CK. Show fewer authors.“Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria.”
PLoS Genetics. 19 December 2018.
Reproduction
Demontis D, Walters RK, Martin J, Mattheisen M, Als TD. et al.Show more authors.Demontis D, Walters RK, Martin J, Mattheisen M, Als TD, Agerbo E, Baldursson G, Belliveau R, Bybjerg-Grauholm J, Bækvad-Hansen M, Cerrato F, Chambert K, Churchhouse C, Dumont A, Eriksson N, Gandal M, Goldstein JI, Grasby KL, Grove J, Gudmundsson OO, Hansen CS, Hauberg ME, Hollegaard MV, Howrigan DP, Huang H, Maller JB, Martin AR, Martin NG, Moran J, Pallesen J, Palmer DS, Pedersen CB, Pedersen MG, Poterba T, Poulsen JB, Ripke S, Robinson E, Satterstrom FK, Stegansson H, Stevens C, Turley P, Walters GB, Won H, Wright MJ, ADHD Working Group of the Psychiatric Genomics Consortium (PGC), Early Lifecourse & Genetic Epidemiology (EAGLE) Consortium, 23andMe Research Team, Andreassen OE, Asherson P, Burton CL, Boomsma DI, Cormand B, Dalsgaard S, franke B, Gelernter J, Geschwind D, Hakonarson H, Haavik J, Kranzler HR, Kuntsi J, Langley K, Lesch K, Middeldorp C, Reif A, Rohde LA, Roussos P, Schachar R, Sklar P, Sonuga-Barke EJS, Sullivan PF, Thapar A, Tung JY, Waldman ID, Medland SE, Stefansson K, Nordentoft M, Hougaard DM, Werge T, Mors O, Mortensen PB, Daly MJ, Faraone SV, Børglum AD, Neale BM. Show fewer authors.“Discovery of the first genome-wide significant risk loci for ADHD.”
Nature Genetics. 26 November 2018.
Psychiatry
Walters RK, Adams MJ, Adkins AE, Aliev F, Bacanu S. et al.Show more authors.Walters RK, Adams MJ, Adkins AE, Aliev F, Bacanu S, Batzler A, Bertelsen S, Biernacka J, Bigdeli TB, Chen L, Clark T, Chou Y, Degenhardt F, Docherty AR, Fontanillas P, Foo J, Fox L, Frank J, Giegling I, Gordon S, Hack L, Hartz S, Heilmann-Heimbach S, Herms S, Hodgkinson C, Hoffmann P, Hottenga J, Kennedy MA, Alanne-Kinnunen M, Knote B, Lahti J, Lahti-Pulkkinen M, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Milaneschi Y, Palviainen T, Pearson J, Peterson R, Polimanti R, Ripatti S, Ryu E, Saccone N, Salvatore J, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang J, Webb BT, Wedow R, Wetherill L, Wills AG, 23andMe Research Team, Boardman J, Chen D, Choi D, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Elson SL, Frye M, Gäbel W, Ising M, Johnson EC, Keyes M, Kiefer F, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Männistö, McClintick JN, Meyers JL, Müller-Myhsok B, Nurnberger JI, Palotie A, Preuss U, Räikkönen K, Reynolds MD, Ridinger M, Scherbaum N, Shuckit M, Soyka M, Treutlein J, Witt S, Wodarz N, Zill P, Adkins D, Boden JM, Boomsma D, Bierut LJ, Brown SA, Bucholz KK, Chicho S, Costello EJ, de Wit H, Diazgranados N, Dick DM, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AA, Goldman D, Grucza RA, Hancock DB, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer C, Horwood J, Iacono W, Johnson EO, Kaprio JA, Karpyak V, Kendler KS, Kranzler HR, Krauter K, Lichtenstein P, Lind PA, McGue M, MacKillop J, Madden PAF, Maes H, Magnusson P, Martin NG, Medland SE, Montgomery GW, Nelson EC, Nöthen M, Palmer AA, Pedersen NL, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose R, Rujescu D, Shen P, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Gelernter J, Edenberg HJ, Agrawal A. Show fewer authors.“Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.”
Nature Neuroscience. 26 November 2018.
Behavior
Orlova E, Yeh A, Shi M, Firek B, Ranganathan S. et al.Show more authors.Orlova E, Yeh A, Shi M, Firek B, Ranganathan S, 23andMe Research Team, Whitcomb DC, Finegold DN, Ferrel RE, Barmada MM, Marazita ML, Hinds DA, Shaffer JR, Morowitz MJ Show fewer authors.“Genetic association and differential expression of PITX2 with acute appendicitis.”
Human Genetics. 3 November 2018.
Immunity
Sanchez-Roige S, Palmer AA, Fontanillas P, Elson S, 23andMe Research Team. et al.Show more authors.Sanchez-Roige S, Palmer AA, Fontanillas P, Elson S, 23andMe Research Team, Substance Use Disorder Working Group of the Psychiatric Genomics Consortium, Adams MJ, Howard DM, Edenberg HJ, Davies G, Crist RC, Deary I, McIntosh AM, Clarke TK Show fewer authors.“Meta-analysis GWAS of the Alcohol Use Disorder Identification Test (AUDIT) in two population based cohorts (N=141,958).”
American Journal of Psychiatry. 19 October 2018.
[bioRxiv]
Behavior
Psychiatry
Diogo D, Tian C, Franklin C, Alanne-Kinnunen M, March M. et al.Show more authors.Diogo D, Tian C, Franklin C, Alanne-Kinnunen M, March M, Spencer C, Vangjeli C, Weale M, Mattsson H, Elina K, Sleiman P, Reilly D, McElwee J, Maranville J, Chatterjee A, Bhandari A, 23andMe Research Team, Reeve M, Hutz J, Bing N, John S, MacArthur D, Salomaa V, Ripatti S, Hakonarson H, Daly M, Palotie A, Hinds D, Donnelly P, Fox C, Day-Williams A, Plenge R, Runz H. Show fewer authors.“Phenome-wide association studies across large ‘real-world data’ population cohorts support drug target validation.”
Nature Communications. 16 October 2018.
Methods
Pasman JA, Verweij KJH, Gerring Z, Stringer S, Sanchez-Roige S. et al.Show more authors.Pasman JA, Verweij KJH, Gerring Z, Stringer S, Sanchez-Roige S, Treur JL, Abdellaoui A, Nivard MG, Baselmans BML, Ong J, Ip HF, van der Zee MD, Bartels M, Day JF, Fontanillas P, Elson SL, the 23andMe Research Team, de Wit H, Davis LK, MacKillop J, International Cannabis Consortium, Derringer JL, Branje SJT, Hartman CA, Heath AC, van Lier PAC, Madden PAF, Magi R, Meeus W, Montgomery GW, Oldehinkel AJ, Pausova Z, Ramos-Quiroga JA, Paus T, Ribases M, Kaprio J, Boks MPM, Bell JT, Spector TD, Gelernter J, Boomsma DI, Martin NG, MacGregor S, Perry JRB, Palmer AA, Posthuma D, Manuafo MR, Gillespie NA, Derks EM, Vink JM. Show fewer authors.“GWAS of lifetime cannabis use reveals new risk loci, genetic overlap with psychiatric traits, and a causal influence of schizophrenia.”
Nature Neuroscience. 27 August 2018.
Behavior
Jones HJ, Heron J, Hammerton G, Stochl J, Jones PB. et al.Show more authors.Jones HJ, Heron J, Hammerton G, Stochl J, Jones PB, Cannon M, Smith GD, Holmans P, Lewis G, Linden DEJ, O'Donovan MC, Owen MJ, Walters J, Zammit S, 23andMe Research Team. Show fewer authors.“Investigating the genetic architecture of general and specific psychopathology in adolescence.”
Translational Psychiatry. 8 August 2018.
Psychiatry
Lee JJ, Wedow RW, Okbay AO, Kong EK, Maghzian OM. et al.Show more authors.Lee JJ, Wedow RW, Okbay AO, Kong EK, Maghzian OM, Zacher MZ, Nguyen-Viet TA, Bowers PB, Sidorenko JS, Linnér RK, Fontana MA, Kundu TK, Lee CL, Li HL, Li RL, Royer RR, Timshel PN, Walters RK, Willoughby EA, Yengo LY, 23andMe Research Team, COGENT (Cognitive Genomics Consortium), Social Science Genetic Association Consortium, Alver MA, Bao YB, Clark DW, Day FR, Furlotte NA, Joshi PK, Kemper KE, Kleinman AK, Langenberg CL, Mägi RM, Trampush JW, Verma SS, Wu YW, Lam ML, Zhao JH, Zheng ZZ, Boardman JD, Campbell HC, Freese JF, Harris KM, Hayward CH, Herd PH, Kumari MK, Lencz TL, Luan JL, Malhotra AK, Metspalu AM, Milani LM, Ong KK, Perry JRB, Porteous DJ, Ritchie MD, Smart MC, Smith BH, Tung JY, Wareham NJ, Wilson JF, Beauchamp JP, Conley DC, Esko TE, Lehrer SF, Magnusson PKE, Oskarsson SO, Pers TH, Robinson MR, Thom KT, Watson CW, Chabris CF, Meyer MN, Laibson DI, Yang JY, Johannesson MJ, Koellinger PD, Turley PT, Visscher PM, Benjamin DJ, Cesarini DC. Show fewer authors.“Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.”
Nature Genetics. 23 July 2018.
Behavior
Waage J, Standl M, Curtin JA, Jessen LE, Thorsen J. et al.Show more authors.Waage J, Standl M, Curtin JA, Jessen LE, Thorsen J, Tian C, Schoettler N, The 23andMe Research Team, AAGC collaborators, Flores C, Abdellaoui A, Ahluwalia TS, Alves AC, Amaral AFS, Antó JM, Arnold A, Barreto-Luis A, Baurecht H, van Beijsterveldt CEM, Bleecker ER, Bonàs-Guarch Boomsma DI, Brix S, Bunyavanich S, Burchard EG, Chen Z, Curjuric I, Custovic A, den Dekker HT, Dharmage SC, Dmitrieva J, Duijts L, Ege MJ, Gauderman WJ, Georges M, Gieger C, Gilliland F, Granell R, Gui H, Hansen T, Heinrich J, Henderson J, Hernandez-Pacheco N, Holt P, Imboden M, VWV Jaddoe, Jarvelin MR, Jarvis DL, Jensen KK, Jónsdóttir I, Kabesch M, Kaprio J, Kumar A, Lee, YALevin AM, Li X, Lorenzo-Diaz F, Melén E, Mercader JM, Meyers DA, Myers R, Nicolae DL, Nohr EA, Palviainen T, Paternoster L, Pennell CE, Pershagen G, Pino-Yanes M, Probst-Hensch NM, Rüschendorf F, Simpson A, Stefansson K, Sunyer J, Sveinbjornsson G, Thiering E, T hompson PJ, Torrent M, Torrents D, Tung JY, Wang CA, Weidinger S, Weiss S, Willemsen G, Williams LK, Ober C, Hinds DA, Ferreira MA, Bisgaard H, Strachan DP, Bønnelykke K. Show fewer authors.“Genome-wide association and HLA fine mapping studies identify risk loci and genetic pathways of allergic rhinitis.”
Nature Genetics. 16 July 2018.
Immunity
Huusko JM, Karjalainen MK, Graham BE, Zhang G, Farrow EG. et al.Show more authors.Huusko JM, Karjalainen MK, Graham BE, Zhang G, Farrow EG, Miller NA, Jacobsson B, Eidem HR, Murray JC, Bedell BB, Breheny PB, Brown NW, Bødker FL, Litterman NK, Jiang P, Russell L, Hinds DA, Hu Y, The 23andMe Research Team, Rokas A, Teramo K, Christensen KC, Williams SM, Rämet M, Kingsmore SF, Ryckman KK, Hallman M, Muglia LJ. Show fewer authors.“Whole exome sequencing reveals HSPA1L as a genetic risk factor for spontaneous preterm birth.”
PLoS Genetics. 12 July 2018.
Reproduction
Nagel M, Jansen PR, Stringer S, Watanabe K, de Leeuw CA. et al.Show more authors.Nagel M, Jansen PR, Stringer S, Watanabe K, de Leeuw CA, Bryois J, Savage JE, Hammerschlag AR, Skene NG, Muñoz-Manchado AB, Agee M, Alipanahi B, Auton A, Bell RK, Bryc K, Elson SL, Fontanillas P, Furlotte NA, Hinds DA, Hromatka BS, Huber KE, Kleinman A, Litterman NK, McIntyre MH, Mountain JL, Noblin ES, Mountain JL, Northover CAM, Pitts SJ, Sathirapongsasuti JF, Sazonova OV, Shelton JF, Shringarpure S, Tian C, Tung JY, Vacic V, Wilson CH, White T, Tiemeier H, Linnarsson S, Hjerling-Leffler J, Polderman TJC, Sullivan PF, van der Sluis S, Posthuma D. Show fewer authors.“Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways.”
Nature Genetics. 25 June 2018.
Behavior
Tedja MS, Wojciechowski R, Hysi PG, Eriksson N, Furlotte NA. et al.Show more authors.Tedja MS, Wojciechowski R, Hysi PG, Eriksson N, Furlotte NA, Verhoeven VJM, Iglesias AI, Meester-Smoor MA, Tompson SW, Fan Q, Khawaja AP, Cheng C, Höhn R, Yamashiro K, Wenocur A, Grazal C, Haller T, Metspalu A, Wedenoja J, Jonas JB, Wang YX, Xie J, Mitchell P, Foster PJ, Klein BEK, Klein R, Paterson AD, Hosseini SM, Shah RL, Williams C, Teo YY, Tham YC, Gupta P, Zhao W, Shi Y, Saw W, Tai E, Sim XL, Huffman JE, Polašek O, Hayward C, Bencic G, Rudan I, Wilson JF, The CREAM Consortium, 23andMe Research Team, UK Biobank Eye and Vision Consortium, Joshi PK, Tsujikawa A, Matsuda F, Whisenhunt KN, Zeller T, van der Spek PJ, Haak R, Meijers-Heijboer H, van Leeuwen EM, Iyengar SK, Lass JH, Hofman A, Rivadeneira F, Uitterlinden AG, Vingerling JR, Lehtimäki T, Raitakari OT, Biino G, Pina Concas M, Schwantes-An T, Igo Jr RP, Cuellar-Partida G, Martin NG, Craig JE, Gharahkhani P, Williams KM, Nag A, Rahi JS, Cumberland PM, Delcourt C, Bellenguez C, Ried JS, Bergen AA, Meitinger T, Gieger C, Wong TY, Hewitt AW, Mackey DA, Simpson CL, Pfeiffer N, Pärssinen O, Baird PN, Vitart V, Amin N, van Duijn CM, Bailey-Wilson JE, Young TL, Saw S, Stambolian D, MacGregor S, Guggenheim JA, Tung JY, Hammond CJ, Klaver CCW Show fewer authors.“Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error.”
Nature Genetics. 28 May 2018.
Traits
Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J. et al.Show more authors.Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu2 D, Lee PH, Turley P, Grenier-Boley B, Chouraki V, Kamatani Y, Berr C, Letenneur L, Hannequin D, Amouyel P, Boland A, Deleuze J, Duron E, Vardarajan BN, Reitz C, Goate AM, Huentelman MJ, Kamboh MI, Larson EB, Rogaeva E, George-Hyslop PS, Hakonarson H, Kukull WA, Farrer LA, Barnes LL, Beach TG, Demirci FY, Head E, Hulette CM, Jicha GA, Kauwe JS, Kaye JA, Leverenz JB, Levey AI, Lieberman AP, Pankratz VS, Poon WW, Quinn JF, Saykin AJ, Schneider LS, Smith AG, Sonnen JA, Stern RA, Van Deerlin VM, Van Eldik LJ, Harold D, Russo G, Rubinsztein DC, Bayer A, Tsolaki M, Proitsi P, Fox NC, Hampel H, Owen MJ, Mead S, Passmore P, Morgan K, Nöthen MM, Rossor M, Lupton MK, Hoffmann P, Kornhuber J, Lawlor B, McQuillin A, Al-Chalabi99 A, Bis JC, Ruiz A, Boada M, Seshadri S, Beiser A, Rice K, van der Lee SJ, De Jager PL, Geschwind DH, Riemenschneider M, Riedel-Heller S, Rotter JI, Ransmayr G, Hyman BT, Cruchaga C, Alegret M, Winsvold B, Palta P, Farh K, Cuenca-Leon E, Furlotte N, Kurth T, Ligthart L, Terwindt GM, Freilinger T, Ran C, Gordon SD, Borck G, Adams HH, Lehtimäki T, Wedenoja J, Buring JE, Schürks M, Hrafnsdottir M, Hottenga J, Penninx B, Artto V, Kaunisto M, Vepsäläinen S, Martin NG, Montgomery GW, Kurki MI, Hämäläinen E, Huang H, Huang J, Sandor C, Webber C, Muller-Myhsok B, Schreiber S, Salomaa V, Loehrer E, Göbel H, Macaya A, Pozo-Rosich P, Hansen T, Werge T, Kaprio J, Metspalu A, Kubisch C, Ferrari MD, Belin AC, van den Maagdenberg AMJM, Zwart J, Boomsma D, Eriksson N, Olesen J, Chasman DI, Nyholt DR, Avbersek A, Baum L, Berkovic S, Bradfield J, Buono R, Catarino CB, Cossette P, Jonghe PD, Depondt C, Dlugos D, Ferraro TN, French J, Hjalgrim H, Jamnadas-Khoda J, Kälviäinen R, Kunz WS, Lerche H, Leu C, Lindhout D, Lo W, Lowenstein D, McCormack M, Møller RS, Molloy A, Ng P, Oliver K, Privitera M, Radtke R, Ruppert A, Sander T, Schachter S, Schankin C, Scheffer I, Schoch S, Sisodiya SM, Smith P, Sperling M, Striano P, Surges R, Thomas GN, Visscher F, Whelan CD, Zara F, Heinzen EL, Marson A, Becker F, Stroink H, Zimprich F, Gasser T, Gibbs R, Heutink P, Martinez M, Morris HR, Sharma M, Ryten M, Mok KY, Pulit S, Bevan S, Holliday E, Attia J, Battey T, Boncoraglio G, Thijs V, Chen W, Mitchell B, Rothwell P, Sharma P, Sudlow C, Vicente A, Markus H, Kourkoulis C, Pera J, Raffeld M, Silliman S, Perica VB, Thornton LM, Huckins LM, Rayner NW, Lewis CM, Gratacos M, Rybakowski F, Keski-Rahkonen A, Raevuori A, Hudson JI, Reichborn-Kjennerud T, Monteleone P, Karwautz A, Mannik K, Baker JH, O’Toole JK, Trace SE, Davis OSP, Helder SG, Ehrlich S, Herpertz-Dahlmann B, Danner UN, van Elburg AA, Clementi M, Forzan M, Docampo E, Lissowska J, Hauser J, Tortorella A, Maj M, Gonidakis F, Tziouvas K, Papezova H, Yilmaz Z, Wagner G, Cohen-Woods S, Herms S, Julià A, Rabionet R, Dick DM, Ripatti S, Andreassen OA, Espeseth T, Lundervold AJ, Steen VM, Pinto D, Scherer SW, Aschauer H, Schosser A, Alfredsson L, Padyukov L, Halmi KA, Mitchell J, Strober M, Bergen AW, Kaye W, Szatkiewicz JP, Cormand B, Ramos-Quiroga JA, Sánchez-Mora C, Ribasés M, Casas M, Hervas A, Arranz MJ, Haavik J, Zayats T, Johansson S, Williams N, Dempfle A, Rothenberger A, Kuntsi J, Oades RD, Banaschewski T, Franke B, Buitelaar JK, Vasquez AA, Doyle AE, Reif A, Lesch K, Freitag C, Rivero O, Palmason H, Romanos M, Langley K, ietschel M, Witt SH, Dalsgaard S, Børglum AD, Waldman I, Wilmot B, Molly N, Bau CH, Crosbie J, Schachar R, Loo SK, McGough JJ, Grevet EH, Medland SE, Robinson E, Weiss LA, Bacchelli E, Bailey A, Bal V, Battaglia A, Betancur C, Bolton P, Cantor R, Celestino-Soper P, Dawson G, Rubeis SD, Duque F, Green A, Klauck SM, Leboyer M, Levitt P, Maestrini E, Mane S, De-Luca DM, Parr J, Regan R, Reichenberg A, Sandin S, Vorstman J, Wassink 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Science. 28 May 2018.
Psychiatry
Gormley P, Kurki MI, Eveliina M, Veerapen K, Happola P. et al.Show more authors.Gormley P, Kurki MI, Eveliina M, Veerapen K, Happola P, Mitchell AA, Lal D, Palta P, Surakka I, Kaunisto MA, Hamalainen E, Vepsalainen S, Havanka H, Harno H, Ilmavirta M, Nissila M, Sako E, Sumelahti M, Liukkonen J, Sillanpaa M, Metsahonkala L, Koskinen S, Lehtimaki T, Raitakari O, Mannikko M, Ran C, Belin AC, Jousilahti P, Anttila V, Salomaa V, Artto V, Farkkila M, 23andMe Research Team, International Headache Genetics Consortium (IHGC), Runz H, Daly MJ, Neale BM, Ripatti S, Kallela M, Wessman M, Palotie A Show fewer authors.“Common variant burden contributes to the familial aggregation of migraine in 1,589 families.”
Neuron. 3 May 2018.
Neurology
Wray NR, Ripke S, Mattheisen M, Trzaskowski M, Byrne EM. et al.Show more authors.Wray NR, Ripke S, Mattheisen M, Trzaskowski M, Byrne EM, Abdellaoui A, Adams MJ, Agerbo E, Air TM, Andlauer FTM, Bacanu S, Bækvad-Hansen M, Beekman TAF, Bigdeli TB, Binder EB, Blackwood DRH, Bryois J, Buttenschøn HN, Bybjerg-Grauholm J, Cai N, Castelao E, Christensen JH, Clarke T, Coleman RJI, Colodro-Conde L, Couvy-Duchesne B, Craddock N, Crawford GE, Crowley CA, Dashti HS, Davies G, Deary IJ, Degenhardt F, Derks EM, Direk N, Dolan CV, Dunn EC, Eley TC, Eriksson N, Escott-Price V, KiadehFarhadi FH, Finucane HK, Forstner AJ, Frank J, Gaspar HA, Gill M, Giusti-Rodríguez P, Goes FS, Gordon SD, Grove J, Hall LS, Hannon E, Hansen CS, Hansen TF, Herms S, HickieI B, Hoffmann P, Homuth G, Horn C, Hottenga J, Hougaard DM, Hu M, Hyde CL, Ising M, Jansen R, Jin F, Jorgenson E, Knowles JA, Kohane IS, Kraft J, Kretzschmar WW, Krogh J, Kutalik Z, Lane JM, Li Y, Li Y, Lind PA, Liu X, Lu L, MacIntyre DJ, MacKinnon DF, Maier RM, Maier W, Marchini J, Mbarek H, McGrath P, McGuffin P, Medland SE, Mehta D, Middeldorp CM, Mihailov E, Milaneschi E, Milani L, Mill J, Mondimore FM, Montgomery GW, Mostafavi S, Mullins N, Nauck M, Ng B, Nivard MG, Nyholt DR, O’Reilly PF, Oskarsson H, Owen MJ, Painter JN, Pedersen CB, Pedersen MG, Peterson RE, Pettersson E, Peyrot WJ, Pistis G, Posthuma D, Purcell SM, Quiroz JA, Qvist P, Rice JP, Riley BP, Rivera M, Mirza SS, Saxena R, Schoevers R, Schulte EC, Shen L, Shi J, Shyn SI, Sigurdsson E, Sinnamon GBC, Smit JH, Smith DJ, Stefansson H, Steinberg S, Stockmeier CA, Streit F, Strohmaier J, Tansey KE, Teismann H, Teumer A, Thompson W, Thomson PA, Thorgeirsson TE, Tian C, Traylor M, Treutlein J, Trubetskoy V, Uitterlinden AG, Umbricht D, Auwerader SV, Hemertvan AM, Viktorin A, Visscher PM, Wang Y, Webb BT, Weinsheimer SM, Wellmann J, Willemsen G, Witt SH, Wu Y, Xi HS, Yang J, Zhang F, eQTLGen, 23andMe, Arolt V, Baune BT, Berger K, Boomsma DI, Cichon S, Dannlowski U, de Geus ECJ, DePaulo JR, Domenici E, Domschke K, Esko T, Grabe HJ, Hamilton SP, Hayward C, Heath AC, Hinds DA, Kendler KS, Kloiber S, Lewis G, Li QS, Lucae S, Madden PFA, Magnusson PK, Martin NG, McIntosh AM, Metspalu A, Mors O, Mortensen PB, Müller-Myhsok B, Nordentoft M, Nöthen MM, O’Donovan MC, Paciga SA, Pedersen NL, H BWJ, Perlis RH, Porteous DJ, Potash JB, Preisig M, Rietschel M, Schaefer C, Schulze TG, Smoller JW, Stefansson K, Tiemeier H, Uher R, Völzke H, Weissman MM, Werge T, Winslow AR, Lewis CM, Levinson DF, Breen G, Børglum AD, Sullivan PF, The Major Depressive Disorder Working of the Psychiatric Genomics Consortium Show fewer authors.“Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.”
Nature Genetics. 26 April 2018.
Psychiatry
Ferreira MAR, Vonk JM, Baurecht H, Marenholz I, Tian C. et al.Show more authors.Ferreira MAR, Vonk JM, Baurecht H, Marenholz I, Tian C, Hoffman JD, Helmer Q, Tillander A, Ullemar V, Lu Y, Rüschendor F, 23andMe Research Team, Hinds DA, Hübner N, Weidinger S, Magnusson PKE, Jorgenson E, Lee Y, Boomsma DI, Karlsson R, Almqvist C, Koppelman GH, Paternoster L Show fewer authors.“Eleven loci with new reproducible genetic associations with allergic disease risk.”
Journal of Allergy and Clinical Immunology. 19 April 2018.
Immunity
Hysi PG, Valdes AM, Liu F, Furlotte NA, Evans DM. et al.Show more authors.Hysi PG, Valdes AM, Liu F, Furlotte NA, Evans DM, Bataille V, Visconti A, Hemani G, McMahon G, Ring SM, Smith GD, Duffy DL, Zhu G, Gordon SD, Medland SE, Lin BD, Willemsen G, Hottenga JJ, Vuckovic D, Girotto G, Gandin I, Sala C, Concas MP, Brumat M, Gasparini P, Toniolo D, Cocca M, Robino A, Yazar S, Hewitt AW, Chen Y, Zeng C, Uitterlinden AG, Ikram MA, Hamer MA, van Duijn CM, Nijsten T, Mackey DA, Falchi M, Boomsma DI, Martin NG, Hinds DA, Kayser M, Spector TD, The International Visible Trait Genetics Consortium Show fewer authors.“A GWAS meta-analysis of more than 300,000 individuals of European ancestry identifies numerous new genetic loci explaining significant portions of hair color variation and heritability.”
Nature Communications. 16 April 2018.
Traits
Howard DM, Adams MJ, Shirali M, Clarke TK, Marioni RE. et al.Show more authors.Howard DM, Adams MJ, Shirali M, Clarke TK, Marioni RE, Davies G, Coleman JRI, Alloza C, Shen X, Barbu MC, Wigmore EM, Gibson J, Agee M, Alipanahi B, Auton A, Bell RK, Bryc K, Elson SL, Fontanillas P, Furlotte NA, Hinds DA, Huber KE, Kleinman A, Litterman NK, McCreight JC, McIntyre MH, Mountain JL, Noblin ES, Northover CAM, Pitts SJ, Sathirapongsasuti JF, Sazonova OV, Shelton JF, Shringarpure S, Tian C, Tung JY, Vacic V, Wilson CH, Hagenaars SP, Lewis CM, Ward J, Smith DJ, Sullivan PF, Haley CS, Breen G, Deary IJ, McIntosh AM Show fewer authors.“Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways.”
Nature Communications. 16 April 2018.
Neurology
Psychiatry
Wu W, the 23andMe Research Team, Amos CI, Lee JE, Wei Q. et al.Show more authors.Wu W, the 23andMe Research Team, Amos CI, Lee JE, Wei Q, Sarin KY, Han J Show fewer authors.“Inverse relationship between vitiligo-related genes and skin cancer risk.”
Journal of Investigative Dermatology. 23 March 2018.
Cancer
Dermatology
Fejzo MS, Sazonova OV, Sathirapongsasuti JF, Hallgrímsdóttir IB, Vacic V. et al.Show more authors.Fejzo MS, Sazonova OV, Sathirapongsasuti JF, Hallgrímsdóttir IB, Vacic V, MacGibbon KW, Schoenberg FP, Mancuso N, Slamon DJ, Mullin PM, Agee M, Alipanahi B, Auton A, Bell RK, Bryc K, Elson SL, Fontanillas P, Furlotte NA, Hinds DA, Hromatka BS, Huber KE, Kleinman A, Litterman NK, McIntyre MH, Noblin ES, Northover CAM, Pitts SJ, Shelton JF, Shringarpure S, Tian C, Tung JY, Wilson CH. Show fewer authors.“Placenta and appetite genes GDF15 and IGFBP7 are associated with hyperemesis gravidarum.”
Nature Communications. 21 March 2018.
Reproduction
Warrier V, Toro R, Chakrabarti B, the iPSYCH-Broad autism group, Børglum AD. et al.Show more authors.Warrier V, Toro R, Chakrabarti B, the iPSYCH-Broad autism group, Børglum AD, Grove J, the 23andMe Research Team, Hinds DA, Bourgeron T, Baron-Cohen S. Show fewer authors.“Genome-wide analyses of self-reported empathy: correlations with autism, schizophrenia, and anorexia nervosa”
Translational Psychiatry. 12 March 2018.
Behavior
Psychiatry
Turley P, Walters RK, Maghzian O, Okbay A, Lee JJ. et al.Show more authors.Turley P, Walters RK, Maghzian O, Okbay A, Lee JJ, Fontana MA, Nguyen-Viet TA, Wedow R, Zacher M, Furlotte NA, Magnusson P, Oskarsson S, Johannesson M, Visscher PM, Laibson D, Cesarini D, Neale BM, Benjamin DJ, 23andMe Research Team, Social Science Genetic Association Consortium Show fewer authors.“Multi-trait analysis of genome-wide association summary statistics using MTAG.”
Nature Genetics. 3 January 2018.
Methods
Shaffer JR, Li J, Lee MK, Roosenboom J, Orlova E. et al.Show more authors.Shaffer JR, Li J, Lee MK, Roosenboom J, Orlova E, Adhikari K, Agee M, Alipanahi B, Auton A, Bell RK, Bryc K, Elson SL, Fontanillas P, Furlotte NA, Hromatka BS, Huber KE, Kleinman A, Litterman NK, McIntyre MH, Mountain JL, Noblin ES, Northover CAM, Pitts SJ, Sathirapongsasuti JF, Sazonova OV, Shelton JF, Shringarpure S, Tian C, Tung JY, Vacic V, Wilson CH, Gallo C, Poletti G, Schuler-Faccini L, Bortolini MC, Canizales-Quinteros S, Rothhammer F, Bedoya G, González-José R, Pfeffer PE, Wollenschlaeger CA, Hecht JT, Wehby GL, Moreno LM, Ding A, Jin L, Yang Y, Carlson JC, Leslie EJ, Feingold E, Marazita ML, Hinds DA, Cox TC, Wang S, Ruiz-Linares A, Weinberg SM Show fewer authors.“Multiethnic GWAS reveals polygenic architecture of earlobe attachment.”
American Journal of Human Genetics. 30 November 2017.
Traits
Ferreira MA, Vonk JM, Baurecht H, Marenholz I, Tian C. et al.Show more authors.Ferreira MA, Vonk JM, Baurecht H, Marenholz I, Tian C, Hoffman JD, Helmer Q, Tillander A, Ullemar V, van Dongen J, Lu Y, Rüschendorf F, Esparza-Gordillo J, Medway CW, Mountjoy E, Burrows K, Hummel O, Grosche S, Brumpton BM, Witte JS, Hottenga JJ, Willemsen G, Zheng J, Rodríguez E, Hotze M, Franke A, Revez JA, Beesley J, Matheson MC, Dharmage SC, Bain LM, Fritsche LG, Gabrielsen ME, Balliu B, 23andMe Research Team, AAGC collaborators, BIOS consortium, LifeLines Cohort Study, Nielsen JB, Zhou W, Hveem K, Langhammer A, Holmen OL, Løset M, Abecasis GR, Willer CJ, Arnold A, Homuth G, Schmidt CO, Thompson PJ, Martin NG, Duffy DL, Novak N, Schulz H, Karrasch S, Gieger C, Strauch K, Melles RB, Hinds DA, Hübner N, Weidinger S, Magnusson PKE, Jansen R, Jorgenson E, Lee YA, Boomsma DI, Almqvist C, Karlsson R, Koppelman GH, Paternoster L Show fewer authors.“Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.”
Nature Genetics. 13 October 2017.
Immunity
Schormair B, Zhao C, Bell S, Tilch E, Salminen AV. et al.Show more authors. Schormair B, Zhao C, Bell S, Tilch E, Salminen AV, Pütz B, Dauvilliers Y, Stefani A, Högl B, Poewe W, Kemlink D, Sonka K, Bachmann CG, Paulus W, Trenkwalder C, Oertel WH, Hornyak M, Teder-Laving M, Metspalu A, Hadjigeorgiou GM, Polo O, Fietze I, Ross OA, Wszolek Z, Butterworth AS, Soranzo N, Ouwehand WH, Roberts DJ, Danesh J, Allen RP, Earley CJ, Ondo WG, Xiong L, Montplaisir J, Gan-Or Z, Perola M, Vodicka P, Dina C, Franke A, Tittmann L, Stewart AFR, Shah SH, Gieger C, Peters A, Rouleau GA, Berger K, Oexle K, Di Angelantonio E, Hinds DA, Müller-Myhsok B, Winkelmann J, 23andMe Research Team, DESIR study group Show fewer authors.“Identification of novel risk loci for restless legs syndrome in genome-wide association studies in individuals of European ancestry: a meta-analysis.”
The Lancet: Neurology. 13 October 2017.
Neurology
Chang D, Nalls MA, Hallgrímsdóttir IB, Hunkapiller J, van der Brug M. et al.Show more authors. Chang D, Nalls MA, Hallgrímsdóttir IB, Hunkapiller J, van der Brug M, Cai F, International Parkinson's Disease Genomics Consortium, 23andMe Research Team, Kerchner GA, Ayalon G, Bingol B, Sheng M, Hinds D, Behrens TW, Singleton AB, Bhangale TR, Graham RR. Show fewer authors.“A meta-analysis of genome-wide association studies identifies 17 new Parkinson’s disease risk loci”
Nature Genetics. 11 September 2017.
Neurology
Zhang G, Feenstra B, Bacelis J, Liu X, Muglia LM. et al.Show more authors. Zhang G, Feenstra B, Bacelis J, Liu X, Muglia LM, Juodakis J, Miller DE, Litterman N, Jiang P, Russell L, Hinds DA, Hu Y, Weirauch MT, Chen X, Chavan AR, Wagner GP, Pavličev M, Nnamani MC, Maziarz J, Karjalainen MK, Rämet M, Sengpiel V, Geller F, Boyd HA, Palotie A, Momany A, Bedell B, Ryckman KK, Huusko JM, Forney CR, Kottyan LC, Hallman M, Teramo K, Nohr EA, Smith GD, Melbye M, Jacobsson B, Muglia LJ. Show fewer authors.“Genetic associations with gestational duration and spontaneous preterm birth”
New England Journal of Medicine. 6 September 2017.
Reproduction
Hellwege JN, Jeff JM, Wise LA, Gallagher CS, Wellons M. et al.Show more authors. Hellwege JN, Jeff JM, Wise LA, Gallagher CS, Wellons M, Hartmann KE, Jones SF, Torstenson ES, Dickinson S, Ruiz-Narváez EA, Rohland N, Allen A, Reich D, Tandon A, Pasaniuc B, Mancuso N, Im HK, Hinds DA, Palmer JR, Rosenberg L, Denny JC, Roden DM, Stewart EA, Morton CC, Kenny EE, Edwards TL, Velez Edwards DR. Show fewer authors.“A multi-stage genome-wide association study of uterine fibroids in African Americans”
Human Genetics. 23 August 2017.
Reproduction
Boutwell B, Hinds D, Agee M, Alipanahi B, Auton A. et al.Show more authors. Boutwell B, Hinds D, Agee M, Alipanahi B, Auton A, Bell RK, Bryc K, Elson SL, Fontanillas P, Furlotte NA, Hromatka BS, Huber KE, Kleinman A, Litterman NK, McIntyre M, Mountain JM, Northerover CAM, Sathiraspongsasuti JF, Sazonova OV, Shelton JF. Shringarpure S, Tian C, Tung JY, Vacic V, Wilson CH, Tielbeek J, Ong KK, Day FR, Perry JRB Show fewer authors.“Replication and characterization of CADM2 and MSRA genes on human behavior.”
Heliyon. 26 July 2017.
Behavior
Sapkota Y, Steinthorsdottir V, Morris AP, Fassbender A, Rahmioglu N. et al.Show more authors. Sapkota Y, Steinthorsdottir V, Morris AP, Fassbender A, Rahmioglu N, De Vivo I, Buring JE, Zhang F, Edwards TL, Jones S, O D, Peterse D, Rexrode KM, Ridker PM, Schork AJ, MacGregor S, Martin NG, Becker CM, Adachi S, Yoshihara K, Enomoto T, Takahashi A, Kamatani Y, Matsuda K, Kubo M, Thorleifsson G, Geirsson RT, Thorsteinsdottir U, Wallace LM, iPSYCH-SSI-Broad Group, Yang J, Velez Edwards DR, Nyegaard M, Low S, Zondervan KT, Missmer SA, D'Hooghe T, Montgomery GW, Chasman I, Stefansson K, Tung JY, Nyholt DR. Show fewer authors.“Meta-analysis of 208,000 individuals identifies 18 risk loci for endometriosis and highlights key genes involved in hormone metabolism.”
Nature Communications. 24 May 2017.
Reproduction
Tsoi LC, Stuart PE, Tian C, Gudjonsson JE, Das S. et al.Show more authors. Tsoi LC, Stuart PE, Tian C, Gudjonsson JE, Das S, Zawistowski M, Ellinghaus E, Barker JN, Chandran V, Dand N, Duffin KC, Enerbäck C, Esko T, Franke A, Gladman DD, Hoffmann P, Kingo K, Kõks S, Krueger GG, Lim HW, Metspalu A, Mrowietz U, Mucha S, Rahman P, Reis A, Tejasvi T, Trembath R, Voorhees JJ, Weidinger S, Weichenthal M, Wen X, Eriksson N, Kang HM, Hinds DA, Nair RP, Abecasis GR, Elder JT. Show fewer authors.“Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants.”
Nature Communications. 24 May 2017.
Dermatology
Immunity
Felix R Day, Deborah J Thompson, Hannes Helgason, Daniel I Chasman, Hilary Finucane. et al.Show more authors. Felix R Day, Deborah J Thompson, Hannes Helgason, Daniel I Chasman, Hilary Finucane, Patrick Sulem, Katherine S Ruth, Sean Whalen, Abhishek K Sarkar, Eva Albrecht, Elisabeth Altmaier, Marzyeh Amini, Caterina M Barbieri, Thibaud Boutin, Archie Campbell, Ellen Demerath, Ayush Giri, Chunyan He, Jouke J Hottenga, Robert Karlsson, Ivana Kolcic, Po-Ru Loh, Kathryn L Lunetta, Massimo Mangino, Brumat Marco, George McMahon, Sarah E Medland, Ilja M Nolte, Raymond Noordam, Teresa Nutile, Lavinia Paternoster, Natalia Perjakova, Eleonora Porcu, Lynda M Rose, Katharina E Schraut, Ayellet V Segre, Albert V Smith, Lisette Stolk, Alexander Teumer, Irene L Andrulis, Stefania Bandinelli, Matthias W Beckmann, Javier Benitez, Sven Bergmann, Murielle Bochud, Eric Boerwinkle, Stig E Bojesen, Manjeet K Bolla, Judith S Brand, Hiltrud Brauch, Hermann Brenner, Linda Broer, Thomas Bruning, Julie E Buring, Harry Campbell, Eulalia Catamo, Stephen Chanock, Georgia Chenevix-Trench, Tanguy Corre, Fergus J Couch, Diana L Cousminer, Angela Cox, Laura Crisponi, Kamila Czene, George Davey Smith, Eco J C N de Geus, Renee de Mutsert, Immaculata De Vivo, Joe Dennis, Peter Devilee, Isabel dos-Santos-Silva, Alison M Dunning, Johan G Eriksson, Peter A Fasching, Lindsay Fernández-Rhodes, Luigi Ferrucci, Dieter Flesch-Janys, Lude Franke, Marike Gabrielson, Ilaria Gandin, Graham G Giles, Harald Grallert, Daniel F Gudbjartsson, Pascal Guenel, Per Hall, Emily Hallberg, Ute Hamann, Tamara B Harris, Catharina A Hartman, Gerardo Heiss, Maartje J Hooning, John L Hopper, Frank Hu, David J Hunter, M Arfan Ikram, Hae Kyung Im, Marjo-Riitta Jarvelin, Peter K Joshi, David Karasik, Manolis Kellis, Zoltan Kutalik, Genevieve LaChance, Diether Lambrechts, Claudia Langenberg, Lenore J Launer, Joop S E Laven, Stefania Lenarduzzi, Jingmei Li, Penelope A Lind, Sara Lindstrom, YongMei Liu, Jian'an Luan, Reedik Magi, Arto Mannermaa, Hamdi Mbarek, Mark I McCarthy, Christa Meisinger, Thomas Meitinger, Cristina Menni, Andres Metspalu, Kyriaki Michailidou, Lili Milani, Roger L Milne, Grant W Montgomery, Anna M Mulligan, Mike A Nalls, Pau Navarro, Heli Nevanlinna, Dale R Nyholt, Albertine J Oldehinkel, Tracy A O'Mara, Sandosh Padmanabhan, Aarno Palotie, Nancy Pedersen, Annette Peters, Julian Peto, Paul D P Pharoah, Anneli Pouta, Paolo Radice, Iffat Rahman, Susan M Ring, Antonietta Robino, Frits R Rosendaal, Igor Rudan, Rico Rueedi, Daniela Ruggiero, Cinzia F Sala, Marjanka K Schmidt, Robert A Scott, Mitul Shah, Rossella Sorice, Melissa C Southey, Ulla Sovio, Meir Stampfer, Maristella Steri, Konstantin Strauch, Toshiko Tanaka, Emmi Tikkanen, Nicholas J Timpson, Michela Traglia, Therèse Truong, Jonathan P Tyrer, André G Uitterlinden, Digna R Velez Edwards, Veronique Vitart, Uwe Volker, Peter Vollenweider, Qin Wang, Elisabeth Widen, Ko Willems van Dijk, Gonneke Willemsen, Robert Winqvist, Bruce H R Wolffenbuttel, Jing Hua Zhao, Magdalena Zoledziewska, Marek Zygmunt, Behrooz Z Alizadeh, Dorret I Boomsma, Marina Ciullo, Francesco Cucca, Tõnu Esko, Nora Franceschini, Christian Gieger, Vilmundur Gudnason, Caroline Hayward, Peter Kraft, Debbie A Lawlor, Patrik K E Magnusson, Nicholas G Martin, Dennis O Mook-Kanamori, Ellen A Nohr, Ozren Polasek, David Porteous, Alkes L Price, Paul M Ridker, Harold Snieder, Tim D Spector, Doris Stockl, Daniela Toniolo, Sheila Ulivi, Jenny A Visser, Henry Volzke, Nicholas J Wareham, James F Wilson, The LifeLines Cohort Study, The InterAct Consortium, kConFab/AOCS Investigators, Endometrial Cancer Association Consortium, Ovarian Cancer Association Consortium, PRACTICAL consortium, Amanda B Spurdle, Unnur Thorsteindottir, Katherine S Pollard, Douglas F Easton, Joyce Y Tung, Jenny Chang-Claude, David Hinds, Anna Murray, Joanne M Murabito, Kari Stefansson, Ken K Ong, John R B Perry. Show fewer authors.“Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility.”
Nature Genetics. 24 April 2017.
Cancer
Reproduction
Heilmann-Heimbach S, Herold C, Hochfeld LM, Hillmer AM, Nyholt DR. et al.Show more authors. Heilmann-Heimbach S, Herold C, Hochfeld LM, Hillmer AM, Nyholt DR, Hecker J, Javed A, Chew EGY, Pechlivanis S, Drichel D, Heng XT, Rosario RCH, Fier HL, Paus R, Rueedi R, Galesloot TE, Moebus S, Anhalt T, Prabhakar S, Li R, Kanoni S, Papanikolaou G, Kutalik Z, Deloukas P, Philpott MP, Waeber G, Spector TD, Vollenweider P, Kiemeney LALM, Dedoussis G, Richards JB, Nothnagel M, Martin NG, Becker T, Hinds DA, Nöthen MM. Show fewer authors.“Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness.”
Nature Communications. 8 March 2017.
Dermatology
Traits
Kreiner E, Waage J, Standl M, Brix S, Pers TH. et al.Show more authors. Kreiner E, Waage J, Standl M, Brix S, Pers TH, Couto Alves A, Warrington NM, Tiesler CM, Fuertes E, Franke L, Hirschhorn JN, James A, Simpson A, Tung JY, Koppelman GH, Postma DS, Pennell CE, Jarvelin MR, Custovic A, Timpson N, Ferreira MA, Strachan DP, Henderson J, Hinds D, Bisgaard H, Bonnelykke K. Show fewer authors.“Shared genetic variants suggest common pathways in allergy and autoimmune diseases.”
Journal of Allergy and Clinical Immunology. 7 February 2017.
Immunity
Trampush JW, Yang ML, Yu J, Knowles E, Davies G. et al.Show more authors. Trampush JW, Yang ML, Yu J, Knowles E, Davies G, Liewald DC, Starr JM, Djurovic S, Melle I, Sundet K, Christoforou A, Reinvang I, DeRosse P, Lundervold AJ, Steen VM, Espeseth T, Raikkonen K, Widen E, Palotie A, Eriksson JG, Giegling I, Konte B, Roussos P, Giakoumaki S, Burdick KE, Payton A, Ollier W, Horan M, Chiba-Falek O, Attix DK, Need AC, Cirulli ET, Voineskos AN, Stefanis NC, Avramopoulos D, Hatzimanolis A, Arking DE, Smyrnis N, Bilder RM, Freimer NA, Cannon TD, London E, Poldrack RA, Sabb FW, Congdon E, Conley ED, Scult MA, Dickinson D, Straub RE, Donohoe G, Morris D, Corvin A, Gill M, Hariri AR, Weinberger DR, Pendleton N, Bitsios P, Rujescu D, Lahti J, Le Hellard S, Keller MC, Andreassen OA, Deary IJ, Glahn DC, Malhotra AK, Lencz T. Show fewer authors.“GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium.”
Molecular Psychiatry. 17 January 2017.
Behavior
Robinson MR, Kleinman A, Graff M, Vinkhuyzen AAE, Couper D. et al.Show more authors. Robinson MR, Kleinman A, Graff M, Vinkhuyzen AAE, Couper D, Miller MB, Peyrot WJ, Abdellaoui A, Zietsch BP, Nolte IM, Vliet-Ostaptchouk JV, Snieder H, The LifeLines Cohort Study, Genetic Investigation of Anthropometric Traits (GIANT) consortium, Medland SE, Martin NG, Magnusson PKE, Iacono WG, McGue M, North KE, Yang J, Visscher PM. Show fewer authors.“Genetic evidence of assortative mating in humans.”
Nature Human Behavior. 9 January 2017.
Lo MT, Hinds DA, Tung JY, Franz C, Fan CC. et al.Show more authors. Lo MT, Hinds DA, Tung JY, Franz C, Fan CC, Wang Y, Smeland OB, Schork A, Holland D, Kauppi K, Sanyal N, Escott-Price V, Smith DJ, O'Donovan M, Stefansson H, Bjornsdottir G, Thorgeirsson TE, Stefansson K, McEvoy LK, Dale AM, Andreassen OA, Chen CH. Show fewer authors.“Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders.”
Nature Genetics. 5 December 2016.
Behavior
Psychiatry
Jones SE, Tyrrell J, Wood AR, Beaumont RN, Ruth KS. et al.Show more authors. Jones SE, Tyrrell J, Wood AR, Beaumont RN, Ruth KS, Tuke MA, Yaghootkar H, Hu Y, Teder-Laving M, Hayward C, Roenneberg T, Wilson JF, Del Greco F, Hicks AA, Shin C, Yun CH, Lee SK, Metspalu A, Byrne EM, Gehrman PR, Tiemeier H, Allebrandt KV, Freathy RM, Murray A, Hinds DA, Frayling TM, Weedon MN. Show fewer authors.“Genome-wide association analyses in 128,266 individuals identifies new morningness and sleep duration loci.”
PLoS Genetics. 5 August 2016.
Behavior
Rietveld CA, Turley P, Chen GB, Emilsson V, Meddens SF. et al.Show more authors. Rietveld CA, Turley P, Chen GB, Emilsson V, Meddens SF, Oskarsson S, Pickrell JK, Thom K, Timshel P, de Vlaming R, Abdellaoui A, Ahluwalia TS, Bacelis J, Baumbach C, Bjornsdottir G, Brandsma JH, Pina Concas M, Derringer J, Furlotte NA, Galesloot TE, Girotto G, Gupta R, Hall LM, Harris SE, Hofer E, Horikoshi M, Huffman JE, Kaasik K, Kalafati IP, Karlsson R, Kong A, Lahti J, van der Lee SJ, deLeeuw C, Lind PA, Lindgren KO, Liu T, Mangino M, Marten J, Mihailov E, Miller MB, van der Most PJ, Oldmeadow C, Payton A, Pervjakova N, Peyrot WJ, Qian Y, Raitakari O, Rueedi R, Salvi E, Schmidt B, Schraut KE, Shi J, Smith AV, Poot RA, St Pourcain B, Teumer A, Thorleifsson G, Verweij N, Vuckovic D, Wellmann J, Westra HJ, Yang J, Zhao W, Zhu Z, Alizadeh BZ, Amin N, Bakshi A, Baumeister SE, Biino G, Bonnelykke K, Boyle PA, Campbell H, Cappuccio FP, Davies G, De Neve JE, Deloukas P, Demuth I, Ding J, Eibich P, Eisele L, Eklund N, Evans DM, Faul JD, Feitosa MF, Forstner AJ, Gandin I, Gunnarsson B, Halldorsson BV, Harris TB, Heath AC, Hocking LJ, Holliday EG, Homuth G, Horan MA, Hottenga JJ, de Jager PL, Joshi PK, Jugessur A, Kaakinen MA, Kahonen M, Kanoni S, Keltigangas-Jarvinen L, Kiemeney LA, Kolcic I, Koskinen S, Kraja AT, Kroh M, Kutalik Z, Latvala A, Launer LJ, Lebreton MP, Levinson DF, Lichtenstein P, Lichtner P, Liewald DC; LifeLines Cohort Study, Loukola A, Madden PA, Magi R, Maki-Opas T, Marioni RE, Marques-Vidal P, Meddens GA, McMahon G, Meisinger C, Meitinger T, Milaneschi Y, Milani L, Montgomery GW, Myhre R, Nelson CP, Nyholt DR, Ollier WE, Palotie A, Paternoster L, Pedersen NL, Petrovic KE, Porteous DJ, Raikkonen K, Ring SM, Robino A, Rostapshova O, Rudan I, Rustichini A, Salomaa V, Sanders AR, Sarin AP, Schmidt H, Scott RJ, Smith BH, Smith JA, Staessen JA, Steinhagen-Thiessen E, Strauch K, Terracciano A, Tobin MD, Ulivi S, Vaccargiu S, Quaye L, van Rooij FJ, Venturini C, Vinkhuyzen AA, Volker U, Volzke H, Vonk JM, Vozzi D, Waage J, Ware EB, Willemsen G, Attia JR, Bennett DA, Berger K, Bertram L, Bisgaard H, Boomsma DI, Borecki IB, Bultmann U, Chabris CF, Cucca F, Cusi D, Deary IJ, Dedoussis GV, van Duijn CM, Eriksson JG, Franke B, Franke L, Gasparini P, Gejman PV, Gieger C, Grabe HJ, Gratten J, Groenen PJ, Gudnason V, van der Harst P, Hayward C, Hinds DA, Hoffmann W, Hypponen E, Iacono WG, Jacobsson B, Jarvelin MR, Jockel KH, Kaprio J, Kardia SL, Lehtimaki T, Lehrer SF, Magnusson PK, Martin NG, McGue M, Metspalu A, Pendleton N, Penninx BW, Perola M, Pirastu N, Pirastu M, Polasek O, Posthuma D, Power C, Province MA, Samani NJ, Schlessinger D, Schmidt R, Sorensen TI, Spector TD, Stefansson K, Thorsteinsdottir U, Thurik AR, Timpson NJ, Tiemeier H, Tung JY, Uitterlinden AG, Vitart V, Vollenweider P, Weir DR, Wilson JF, Wright AF, Conley DC, Krueger RF, Davey Smith G, Hofman A, Laibson DI, Medland SE, Meyer MN, Yang J, Johannesson M, Visscher PM, Esko T, Koellinger PD, Cesarini D, Benjamin DJ. Show fewer authors.“Genome-wide association study identifies 74 loci associated with educational attainment.”
Nature. 11 May 2016.
Behavior
Okbay A, Beauchamp JP, Fontana MA, Lee JJ, Pers TH. et al.Show more authors. Okbay A, Beauchamp JP, Fontana MA, Lee JJ, Pers TH, Fontana MA, Meddens SF, Linner RK, Rietveld CA, Derringer J, Gratten J, Lee JJ, Liu JZ, de Vlaming R, Ahluwalia TS, Buchwald J, Cavadino A, Frazier-Wood AC, Furlotte NA, Garfield V, Geisel MH, Gonzalez JR, Haitjema S, Karlsson R, van der Laan SW, Ladwig KH, Lahti J, van der Lee SJ, Lind PA, Liu T, Matteson L, Mihailov E, Miller MB, Minica CC, Nolte IM, Mook-Kanamori D, van der Most PJ, Oldmeadow C, Qian Y, Raitakari O, Rawal R, Realo A, Rueedi R, Schmidt B, Smith AV, Stergiakouli E, Tanaka T, Taylor K, Wedenoja J, Wellmann J, Westra HJ, Willems SM, Zhao W; LifeLines Cohort Study, Amin N, Bakshi A, Boyle PA, Cherney S, Cox SR, Davies G, Davis OS, Ding J, Direk N, Eibich P, Emeny RT, Fatemifar G, Faul JD, Ferrucci L, Forstner A, Gieger C, Gupta R, Harris TB, Harris JM, Holliday EG, Hottenga JJ, De Jager PL, Kaakinen MA, Kajantie E, Karhunen V, Kolcic I, Kumari M, Launer LJ, Franke L, Li-Gao R, Koini M, Loukola A, Marques-Vidal P, Montgomery GW, Mosing MA, Paternoster L, Pattie A, Petrovic KE, Pulkki-Raback L, Quaye L, Raikkonen K, Rudan I, Scott RJ, Smith JA, Sutin AR, Trzaskowski M, Vinkhuyzen AE, Yu L, Zabaneh D, Attia JR, Bennett DA, Berger K, Bertram L, Boomsma DI, Snieder H, Chang SC, Cucca F, Deary IJ, van Duijn CM, Eriksson JG, Bultmann U, de Geus EJ, Groenen PJ, Gudnason V, Hansen T, Hartman CA, Haworth CM, Hayward C, Heath AC, Hinds DA, Hypponen E, Iacono WG, Jarvelin MR, Jockel KH, Kaprio J, Kardia SL, Keltikangas-Jarvinen L, Kraft P, Kubzansky LD, Lehtimaki T, Magnusson PK, Martin NG, McGue M, Metspalu A, Mills M, de Mutsert R, Oldehinkel AJ, Pasterkamp G, Pedersen NL, Plomin R, Polasek O, Power C, Rich SS, Rosendaal FR, den Ruijter HM, Schlessinger D, Schmidt H, Svento R, Schmidt R, Alizadeh BZ, Sorensen TI, Spector TD, Steptoe A, Terracciano A, Thurik AR, Timpson NJ, Tiemeier H, Uitterlinden AG, Vollenweider P, Wagner GG, Weir DR, Yang J, Conley DC, Smith GD, Hofman A, Johannesson M, Laibson DI, Medland SE, Meyer MN, Pickrell JK, Esko T, Krueger RF, Beauchamp JP, Koellinger PD, Benjamin DJ, Bartels M, Cesarini D. Show fewer authors.“Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.”
Nature Genetics. 18 April 2016.
Behavior
Psychiatry
Chen R, Shi L, Hakenberg J, Naughton B, Sklar P. et al.Show more authors. Chen R, Shi L, Hakenberg J, Naughton B, Sklar P, Zhang J, Zhou H, Tian L, Prakash O, Lemire M, Sleiman P, Cheng WY, Chen W, Shah H, Shen Y, Fromer M, Omberg L, Deardorff MA, Zackai E, Bobe JR, Levin E, Hudson TJ, Groop L, Wang J, Hakonarson H, Wojcicki A, Diaz G, Edelmann L, Schadt EE, Friend SH. Show fewer authors.“Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases.”
Nature Biotechnology. 11 April 2016.
Rare Diseases
Hinds DA, Buil A, Ziemek D, Martinez-Perez A, Malik R. et al.Show more authors. Hinds DA, Buil A, Ziemek D, Martinez-Perez A, Malik R, Folkersen L, Germain M, Malarstig A, Brown A, Soria JM, Dichgans M, Bing N, Franco-Cereceda A, Souto JC, Dermitzakis ED, Hamsten A, Worrall BB, Tung JY, METASTROKE Consortium, INVENT Consortium, Sabater-Lleal M. Show fewer authors.“Genome-wide association analysis in 6,135 individuals and 252,827 controls identifies 8 loci associated with thrombosis.”
Human Molecular Genetics. 9 February 2016.
Hematology
Minikel EV, Vallabh SM, Lek M, Estrada K, Samocha KE. et al.Show more authors. Minikel EV, Vallabh SM, Lek M, Estrada K, Samocha KE, Sathirapongsasuti JF, McLean CY, Tung JY, Yu LP, Gambetti P, Blevins J, Zhang S, Cohen Y, Chen W, Yamada M, Hamaguchi T, Sanjo N, Mizusawa H, Nakamura Y, Kitamoto T, Collins SJ, Boyd A, Will RG, Knight R, Ponto C, Zerr I, Kraus TF, Eigenbrod S, Giese A, Calero M, de Pedro-Cuesta J, Haik S, Laplanche JL, Bouaziz-Amar E, Brandel JP, Capellari S, Parchi P, Poleggi A, Ladogana A, O'Donnell-Luria AH, Karczewski KJ, Marshall JL, Boehnke M, Laakso M, Mohlke KL, Kahler A, Chambert K, McCarroll S, Sullivan PF, Hultman CM, Purcell SM, Sklar P, van der Lee SJ, Rozemuller A, Jansen C, Hofman A, Kraaij R, van Rooij JG, Ikram MA, Uitterlinden AG, van Duijn CM; Exome Aggregation Consortium (ExAC), Daly MJ, MacArthur DG. Show fewer authors.“Quantifying prion disease penetrance using large population control cohorts.”
Science Translational Medicine. 20 January 2016.
Neurology
Rare Diseases
Paternoster L, Standl M, Waage J, Baurecht H, Hotze M. et al.Show more authors. Paternoster L, Standl M, Waage J, Baurecht H, Hotze M, Strachan DP, Curtin JA, Bonnelykke K, Tian C, Takahashi A, Esparza-Gordillo J, Alves AC, Thyssen JP, den Dekker HT, Ferreira MA, Altmaier E, Sleiman PMA, Xiao FL, Gonzalez JR, Marenholz I, Kalb B, Pino-Yanes M, Xu CJ, Carstensen L, Groen-Blokhuis MM, Venturini C, Pennell CE, Barton SJ, Levin AM, Curjuric I, Bustamante M, Kreiner-Moller E, Lockett GA, Bacelis J, Bunyavanich S, Myers RA, Matanovic A, Kumar A, Tung JY, Hirota T, Kubo M, McArdle WL, Henderson AJ, Kemp JP, Zheng J, Smith GD, Ruschendorf F, Bauerfeind A, Lee-Kirsch MA, Arnold A, Homuth G, Schmidt CO, Mangold E, Cichon S, Keil T, Rodriguez E, Peters A, Franke A, Lieb W, Novak N, Folster-Holst R, Horikoshi M, Pekkanen J, Sebert S, Husemoen LL, Grarup N, de Jongste JC, Rivadeneira F, Hofman A, Jaddoe VWV, Pasmans SGMA, Elbert NJ, Uitterlinden AG, Marks GB, Thompson PJ, Matheson MC, Robertson CF, Australian Asthma Genetics Consortium (AAGC), Ried JS, Li J, Zuo XB, Zheng XD, Yin XY, Sun LD, McAleer MA, O'Regan GM, Fahy CMR, Campbell LE, Macek M, Kurek M, Hu D, Eng C, Postma D, Feenstra B, Geller F, Hottenga JJ, Middeldorp CM, Hysi P, Bataille V, Spector T, Tiesler CMT, Thiering E, Pahukasahasram B, Yang JJ, Imboden M, Huntsman S, Vilor-Tejedor N, Relton CL, Myhre R, Nystad W, Custovic A, Weiss ST, Meyers DA, Soderhall C, Melen E, Ober C, Raby BA, Simpson A, Jacobsson B, Holloway JW, Bisgaard H, Sunyer J, Probst-Hensch NM, Williams LK, Godfrey KM, Wang CA, Boomsma DI, Melbye M, Koppelman GH, Jarvis D, McLean WHI, Irvine AD, Zhang XJ, Hakonarson H, Gieger C, Burchard EG, Martin NG, Duijts L, Linneberg A, Jarvelin MR, Nothen MM, Lau S, Hubner N, Lee YA, Tamari M, Hinds DA, Glass D, Brown SJ, Heinrich J, Evans DM, and Stephan Weidinger for the EArly Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium. Show fewer authors.“Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis.”
Nature Genetics. 19 October 2015.
Dermatology
Immunity
Day FR, Hinds DA, Tung JY, Stolk L, Styrkarsdottir U. et al.Show more authors. Day FR, Hinds DA, Tung JY, Stolk L, Styrkarsdottir U, Saxena R, Bjonnes A, Broer L, Dunger DB, Halldorsson BV, Lawlor DA, Laval G, Mathieson I, McCardle WL, Louwers Y, Meun C, Ring S, Scott RA, Sulem P, Uitterlinden AG, Wareham NJ, Thorsteinsdottir U, Welt C, Stefansson K, Laven JSE, Ong KK, Perry JRB. Show fewer authors.“Causal mechanisms and balancing selection inferred from genetic associations with the Polycystic Ovary Syndrome.”
Nature Communications. 25 September 2015.
Reproduction
Zheng HF, Forgetta V, Hsu YH, Estrada K, Rosello-Diez A. et al.Show more authors. Zheng HF, Forgetta V, Hsu YH, Estrada K, Rosello-Diez A, Leo PJ, Dahia CL, Park-Min KH, Tobias JH, Kooperberg C, Kleinman A, Styrkarsdottir U, Liu CT, Uggla C, Evan DS, Nielson CM, Walter K, Pettersson-Kymmer U, McCarthy S, Eriksson J, Kwan T, Jhamai M, Trajanoska K, Memari Y, Min J, Huang J, Danecek P, Wilmot B, Li R, Chou WC, Mokry LE, Moayyeri A, Claussnitzer M, Cheng CH, Cheung W, Medina-Gomez C, Ge B, Chen SH, Choi K, Oei L, Fraser J, Kraaij R, Hibbs MA, Gregson CL, Paquette D, Hofman A, Wibom C, Tranah GJ, Marshall M, Gardiner BB, Cremin K, Auer P, Hsu L, Ring S, Tung JY, Thorleifsson G, Enneman AW, van Schoor NM, de Groot LCPGM, van der Velde N, Melin B, Kemp JP, Christiansen C, Sayers A, Zhou Y, Calderari S, van Rooij J, Carlson C, Peters U, Berlivet S, Dostie J, Uitterlinden AG, Williams SR, Farber C, Grinberg D, LaCroix AZ, Haessler J, Chasman DI, Giulianini F, Rose LM, Ridker PM, Eisman JA, Nguyen TV, Center JR, Nogues X, Garcia-Giralt N, Launer LL, Gudnason V, Mellstrom D, Vandenput L, Amin N, van Duijn CM, Karlsson MK, Ljunggren O, Svensson O, Hallmans G, Rousseau F, Giroux S, Bussiere J, Arp PP, Koromani F, Prince RL, Lewis JR, Langdahl BL, Hermann AP, Jensen JEB, Kaptoge S, Khaw KT, Reeve J, Formosa MM, Xuereb-Anastasi A, Akesson K, McGuigan FE, Garg G, Olmos JM, Zarrabeitia MT, Riancho JA, Ralston SH, Alonso N, Jiang X, Goltzman D, Pastinen T, Grundberg E, Gauguier D, Orwoll ES, Karasik D, Davey-Smith G, AOGC Consortium, Smith AV, Siggeirsdottir K, Harris TB, Zillikens MC, van Meurs JBJ, Thorsteinsdottir U, Maurano MT, Timpson NJ, Soranzo N, Durbin R, Wilson SG, Ntzani EE, Brown MA, Stefansson Kari, Hinds DA, Spector T, Cupples LA, Ohlsson C, Greenwood CMT, UK10K Consortium, Jackson RD, Rowe DW, Loomis CA, Evans DM, Ackert-Bicknell CL, Joyner AL, Duncan EL, Kiel DP, Rivadeneira F, Richards JB. Show fewer authors.“Whole-genome sequencing and deep imputation identifies non-coding variants near Engrailed-1 with large effects on bone mineral density and fracture.”
Nature. 14 September 2015.
Musculoskeletal
Nalls MA, McLean CY, Rick J, Eberly S, Hutten SJ. et al.Show more authors.Nalls MA, McLean CY, Rick J, Eberly S, Hutten SJ, Gwinn K, Sutherland M, Martinez M, Heutink P, Williams NM, Hardy J, Gasser T, Brice A, Price TR, Nicolas A, Keller MF, Molony C, Gibbs JR, Chen-Plotkin A, Suh E, Letson C, Fiandaca MS, Mapstone M, Federoff HJ, Noyce AJ, Morris H, Van Deerlin VM, Weintraub D, Zabetian C, Hernandez DG, Lesage S, Mullins M, Conley ED, Northover CAM, Frasier M, Marek K, Day-Williams AG, Stone DJ, Ioannidis JPA, Singleton AB, for the Parkinson's Disease Biomarkers Program and Parkinson's Progression Marker Initiative investigators Show fewer authors.“Diagnosis of Parkinson’s disease on the basis of clinical and genetic classification: a population-based modelling study.”
Lancet Neuro. 10 August 2015.
Neurology
Lunetta KL, Day FR, Sulem P, Ruth KS, Tung JY. et al.Show more authors. Lunetta KL, Day FR, Sulem P, Ruth KS, Tung JY, Hinds DA, Esko T, Elks CE, Altmaier E, He C, Huffman JE, Mihailov E, Porcu E, Robino A, Rose LM, Schick UM, Stolk L, Teumer A, Thompson DJ, Traglia M, Wang CA, Yerges-Armstrong LM, Antoniou AC, Barbieri C, Coviello AD, Cucca F, Demerath EW, Dunning AM, Gandin I, Grove ML, Gudbjartsson DF, Hocking LJ, Hofman A, Huang J, Jackson RD, Karasik D, Kriebel J, Lange EM, Lange LA, Langenberg C, Li X, Luan J, Magi R, Morrison AC, Padmanabhan S, Pirie A, Polasek O, Porteous D, Reiner AP, Rivadeneira F, Rudan I, Sala CF, Schlessinger D, Scott RA, Stockl D, Visser JA, Volker U, Vozzi D, Wilson JG, Zygmunt M, EPIC-InterAct Consortium, Generation Scotland, Boerwinkle E, Buring JE, Crisponi L, Easton DF, Hayward C, Hu FB, Liu S, Metspalu A, Pennell CE, Ridker PM, Strauch K, Streeten EA, Toniolo D, Uitterlinden AG, Ulivi S, Volzke H, Wareham NJ, Wellons M, Franceschini N, Chasman DI, Thorsteinsdottir U, Murray A, Stefansson K, Murabito JM, Ong KK, Perry JRB. Show fewer authors.“Rare coding variants and X-linked loci associated with age at menarche.”
Nature Communications. 4 August 2015.
Reproduction
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Genome Medicine. 1 August 2015.
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Neuron. 3 June 2015.
Neurology
Psychiatry
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Journal of Investigative Dermatology. 12 March 2015.
Dermatology
Immunity
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Neurobiology of Aging. 4 August 2014.
Neurology
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Nature Genetics. 27 July 2014.
Neurology
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Journal of Allergy and Clinical Immunology. 31 December 2013.
Immunity
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Journal of Data Mining in Genomics & Proteomics. 20 October 2013.
Methods
Revez JA, Bain L, Chapman B, Powell JE, Jansen R. et al.Show more authors. Revez JA, Bain L, Chapman B, Powell JE, Jansen R, Duffy DL, Tung JY, AAGC Collaborators, Penninx BW, Visscher PM, De Geus EJC, Boomsma DI, Hinds DA, Martin NG, Montgomery GW, Ferreira MAR. Show fewer authors.“A new regulatory variant in the interleukin-6 receptor gene associates with asthma risk.”
Genes and Immunity. 15 August 2013.
Immunity
Pichler I, Del Greco M. F, Gogele M, Lill CM, Bertram L. et al.Show more authors.Pichler I, Del Greco M. F, Gogele M, Lill CM, Bertram L, Do CB, Eriksson N, Foroud T, Myers RH, PD GWAS Consortium, Nalls M, Keller MF, International Parkinson's Disease Genomics Consortium, Wellcome Trust Case Control Consortium 2, Benyamin B, Whitfield JB, Genetics of Iron Status Consortium, Pramstaller PP, Hicks AA, Thompson JR, Minelli C Show fewer authors.“Serum iron levels and the risk of Parkinson’s disease: a Mendelian randomization study.”
PLOS Medicine. 4 June 2013.
Neurology
Heilmann S, Kiefer AK, Fricker N, Drichel D, Hillmer AM. et al.Show more authors. Heilmann S, Kiefer AK, Fricker N, Drichel D, Hillmer AM, Herold C, Tung JY, Eriksson N, Redler S, Betz RC, Li R, Karason A, Nyholt DR, Song K, Vermeulen SH, Kanoni S, Dedoussis G, Martin NG, Kiemeny LA, Mooser V, Stefansson K, Richards JB, Becker T, Brockschmidt FF, Hinds DA, Nothen MM. Show fewer authors.“Androgenetic alopecia: identification of four new genetic risk loci and evidence for the contribution of WNT-signaling to its etiology.”
Journal of Investigative Dermatology. 28 January 2013.
Dermatology
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Dermatology
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PLoS Genetics. 15 March 2012.
Neurology
Henn BM, Gignoux CR, Jobin M, Granka JM, Macpherson JM. et al.Show more authors. Henn BM, Gignoux CR, Jobin M, Granka JM, Macpherson JM, Kidd JM, Rodriguez-Botigue L, Ramachandran S, Hon L, Brisbin A, Lin AA, Underhill PA, Comas D, Kidd KK, Norman PJ, Parham P, Bustamante CD, Mountain JL, Feldman MW. Show fewer authors.“Hunter-gatherer genomic diversity suggests a southern African origin for modern humans.”
PNAS. 1 March 2011.
Ancestry
